Monkeypox Myocarditis; Early DOACs After Stroke; Saturated Fats Absolved?


Recent developments of interest in cardiovascular medicine

Electrocardiogram on top and bottom of image with CardioBreak in the center.

The American College of Cardiology said clinicians should be on the lookout for heart problems in patients with monkeypox after a 31-year-old man developed acute myocarditis.

Lingering cardiac symptoms in people who initially had only mild COVID-19 may be driven by ongoing inflammatory myopericardial involvement, according to a single-center study from Germany. (Nature Medicine)

Stroke survivors with atrial fibrillation (Afib) fared no worse when starting direct oral anticoagulant (DOAC) therapy in the first few days as opposed to on a delayed basis, a randomized trial showed. (Circulation)

The association between shift work and incident Afib: does it hinge on age? (Open Heart)

Heavy drinkers ages 20 to 39 in Korea were at higher risk for incident Afib in the long run. (JAMA Network Open)

A review of the available evidence cast doubt on the cardiovascular harms of eating saturated fat. (European Journal of Preventive Cardiology)

In the rural U.S., ST-segment elevation myocardial infarction care was of arguably lower quality, but did not result in higher adjusted in-hospital mortality. (JAMA Cardiology)

Do left ventricular ejection fraction cutoffs for intervention need to be revised upward for bicuspid aortic valve disease? (Journal of the American College of Cardiology)

Just a stethoscope and machine learning software can be enough to identify aortic stenosis in a low-resource setting. (Journal of Applied Physics)

The FDA approved new labeling for the Watchman FLX, such that patients may take 45 days of dual antiplatelet therapy instead of oral anticoagulation after implant, Boston Scientific announced.

There may be particular problems recognizing precapillary pulmonary hypertension in older people. (Journal of the American Heart Association)

Medical bills for people with cardiovascular disease were higher with Medicare Advantage compared with traditional Medicare. (Circulation: Cardiovascular Quality and Outcomes)

In HAUSER-OLE, pediatric patients with heterozygous familial hypercholesterolemia treated with evolocumab (Repatha) had LDL cholesterol levels fall by an average 35.3% from baseline to 80 weeks, compared with the previously reported 44.5% reduction at week 24. (The Lancet Diabetes & Endocrinology)

In adults with congenital heart disease, dyslipidemia appears to be highly prevalent yet underdiagnosed. (JACC: Advances)

Restricting sulfur‐containing amino acid intake did not prevent acute kidney injury after cardiac surgery. (Journal of the American Heart Association)

Novartis was hit with a patent infringement lawsuit related to sacubitril/valsartan (Entresto) while also fighting various generic manufacturers off its turf.

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