Risky Virus Research Renewed

Gain-of-function genetic manipulation can enhance the transmissibility or lethality of viruses

The federal government is lifting the 3-year-old ban on research that involves genetic manipulation of viruses in ways that could enhance their transmissibility or potential lethality, according to a report in STAT.

Research into so-called “gain of function” genetic changes was put on hold after accidents at government facilities involving anthrax and avian flu. These experiments are intended to anticipate future changes in viruses such as Ebola and avian influenza that might result in devastating pandemics, and to help researchers develop strategies to prevent such events.

 But some scientists are skeptical, suggesting that the potential for future accidents remains, such as if a lab worker accidentally becomes infected with a deadly virus that has been altered to permit airborne transmission.