Vitamin and Mineral Supplements –What Clinicians Need to Know : JAMA


https://speciality.medicaldialogues.in/all-you-need-to-know-about-use-of-vitamin-and-mineral-supplements/

Deficiency of this Vitamin Causes Migraines and Headaches.


 

Migraines are really bad. They are horrible. You can’t do anything when a migraine is in full force.

You would do anything to get pass them. You can’t deal with them anymore. The pain became immune on the pills you take.

There could be a solution to this.

migraines

Have you ever heard that your headaches could be a result of vitamin deficiency?

Yep, if you have Vitamin B deficiency there are higher chances your headache won’t stop.

Studies show how Vitamin B deficiency leads to the higher occurrence of migraines. It comes slowly and it takes time to be developed. The symptoms come really slow and you often say it’s nothing.

Like this study here that comes from Harvard.

All these symptoms often result with a headache. This means that taking pills for a headache was wrong all the time. Even though they work, periodically.

Another study tested 52 people who regularly get migraines. It showed that people who were given vitamin supplements noticed a migraine reduction.

The others who were given placebos did not notice reductions at all.

For this study, Professor Griffiths said:

“The success of our trail has shown that safe, inexpensive vitamin supplements can treat migraine patients.”

Migraines are not just a common pain in your head. There are other symptoms, too. Some of them include nausea, vomiting, sensitivity to sound and light, anxiety, etc.

If Vitamin B deficiency is what causes your migraines, you need to keep that vitamin B level up at all cost.

You can do that by taking supplements or foods rich with this vitamin.

Here is a list of foods you need to consume:

  •      Broccoli
  •      Spinach
  •      Asparagus
  •      Fresh and Dried Fruit
  •      Vegetables
  •      Liver
  •      Chicken
  •      Peanuts
  •      Potatoes
  •      Milk
  •      Fish
  •      Rice

If you don’t suffer from migraines, you probably know someone who is. Share this with them. They could finally find the cure.

The Deficiency of this Vitamin Causes Migraines. Here is How to fix it


Migraines are really bad. They are horrible. You can’t do anything when a migraine is in full force.

You would do anything to get pass them. You can’t deal with them anymore. The pain became immune on the pills you take.

There could be a solution to this.

Have you ever heard that your headaches could be a result of vitamin deficiency?

Yep, if you have Vitamin B deficiency there are higher chances your headache won’t stop.

Studies show how Vitamin B deficiency leads to the higher occurrence of migraines. It comes slowly and it takes time to be developed. The symptoms come really slow and you often say it’s nothing.

Like this study here that comes from Harvard.

1

All these symptoms often result with a headache. This means that taking pills for a headache was wrong all the time. Even though they work, periodically.

Another study tested 52 people who regularly get migraines. It showed that people who were given vitamin supplements noticed a migraine reduction.

The others who were given placebos did not notice reductions at all.

For this study, Professor Griffiths said:

2

Migraines are not just a common pain in your head. There are other symptoms, too. Some of them include nausea, vomiting, sensitivity to sound and light, anxiety, etc.

If Vitamin B deficiency is what causes your migraines, you need to keep that vitamin B level up at all cost.

You can do that by taking supplements or foods rich with this vitamin.

earthfoods.info

earthfoods.info

Here is a list of foods you need to consume:

  •      Broccoli
  •      Spinach
  •      Asparagus
  •      Fresh and Dried Fruit
  •      Vegetables
  •      Liver
  •      Chicken
  •      Peanuts
  •      Potatoes
  •      Milk
  •      Fish
  •      Rice

If you don’t suffer from migraines, you probably know someone who is. Share this with them. They could finally find the cure.

Vitamin pills are a waste of money, offer no health benefits and could be harmful – study


Evidence from the study suggested that ‘supplementing the diet of well-nourished adults…has no clear benefit and might even be harmful’

Vitamin pills are a waste of money, usually offer no health benefits and could even be harmful, a group of leading scientists has said.

A study of nearly 500,000 people, carried out by academics from the University of Warwick and the Johns Hopkins School of Medicine in Baltimore, USA, has delivered a damning verdict on the claims made by the vitamin supplement industry.

Evidence from the study suggested that “supplementing the diet of well-nourished adults…has no clear benefit and might even be harmful”, despite one in three Britons taking vitamins or mineral pills.

According to The Times, scientists involved in the study, which was published in the Annals of Internal Medicine, concluded that companies selling supplements were fuelling false health anxieties to offer unnecessary cures. The industry in the UK is thought to be worth more than £650 million annually.

Researchers declared ‘case closed’ on the vitamin and mineral pills after making their conclusion based on the study of half-a-million people along with three separate research papers.

Evidence from the study suggested that

Evidence from the study suggested that “supplementing the diet of well-nourished adults…has no clear benefit and might even be harmful”, despite one in three Britons taking vitamins or mineral pills.

One of the research papers involved the retrospective study of 24 previous trials. In total 450,000 people were involved in the trials and the paper concluded that there was no beneficial effect on mortality from taking vitamins.

Another examined 6,000 elderly men and found no improvement on cognitive decline after 12 years of taking supplements, while a third saw no advantage of supplements among 1,700 men and women with heart problems over an average study of five years.

The experts said most supplements should be avoided as their use is not justified, writing: “These vitamins should not be used for chronic disease prevention. Enough is enough.”

The scientists argued that the average Western diet is sufficient to provide the necessary vitamins the body needs.

Edgar Miller, of the Johns Hopkins School of Medicine, said: “There are some that advocate we have many nutritional deficiencies in our diet. The truth is though we are in general overfed, our diet is completely adequate.”

He added: “These companies are marketing products to us based on perceptions of deficiencies. They make us think our diet is unhealthy, and that they can help us make up for these deficiencies and stop chronic illnesses.

“The group that needs these is very small. It’s not the general population.”

Dr Miller continued: “There’s something for everything: preventing joint pains, stopping heart disease. If you’re going to spend your money on something every month, is this really the best option?”

The NHS advised recently that other than women taking folic acid to help them conceive and the elderly and children under five benefiting from vitamin D, supplementary vitamins would be surplus to that already gained through diet, The Times said.

The Health Food Manufacturers’ Association said vitamin supplements provided people with “nutritional insurance”.

In July 2011 the Advertising Standards Agency criticised Vitabiotics Ltd for an advert headlined: ‘Advanced Nutrients For The Brain’.

They ruled that the implied claims that “recent research had shown that B vitamins could help maintain brain function and performance’ were not substantiated and were “misleading”.

Free vitamins for all under-fives advised by chief medical officer


Vitamin pills

All under-fives may be offered free vitamins on the NHS in an effort to curb the rising tide of illness, such as rickets, linked to them getting too little vitamin D.

Dame Sally Davies, the government’s chief medical officer, wants ministers to consider extending the offer from low-income families to all children under the age of five.

She has asked the National Institute of Health and Care Excellence (NICE) to investigate whether giving all children in that age group vitamins A, C and D, in the form of drops or tablets, would be cost effective.

Davies said the return of rickets, and the implication of vitamin D in other ill-health, meant that offering every family with under-fives free vitamins was necessary.

She pointed to a scheme in Birmingham in which universal access to vitamins is credited with halving the number of cases of rickets in the city.

As many as 40% of young children do not get enough vitamin D, said Davies, as she launched her annual report into children’s health and the state of NHS physical and mental health services for children.

The number of under-18s who have been admitted to hospital in England for rickets soared from 190 in 2002-03 to 748 in 2011-12, NHS figures show.

Hilary Cass, president of the Royal College of Paediatrics and Child Health, welcomed Davies’ initiative but cautioned that take-up of free vitamins under the Healthy Start programme had been less than 10%, according to a study in 13 NHS trust areas published in May. It offers the vitamins to people on low incomes and to pregnant women.

However, she added: “Widespread supplementation is already happening in some countries and should certainly be looked at in the UK.

“We are seeing a growing number of cases of vitamin-D related illnesses amongst children and young people, and supplementation is a key way of getting the required amount.

“Of course we need to see how cost effective it would be to offer these vitamins free to everyone; but quite often the benefits outweigh the costs.”

Seizures and developmental delay in babies are also associated with a lack of vitamin D, which is obtained naturally from sun on the skin and certain foods, such as eggs and oily fish.

Claire Lemer, editor of the report, said: “There is no single reason why parents do not give their children vitamins.

“It could be due to a range of reasons – from not being aware of their benefits to them not being easily accessible.

“But we do know from studies that making vitamins available to all can lead to a boost in families taking up the offer.”

Surprising facts about carrots.


Daucus carota subsp. sativus, commonly known as the carrot, is a vegetable that is naturally healthy, sweet and delicious. These taproots are filled with a lot of compounds that are good for the health, such as antioxidants, vitamin A, minerals and beta-carotenes. These crunchy roots are a common favorite among a lot of people who love vegetables.

Carrots are cultivated all over the world for their taproots. The plant is known to be biennial in nature and starts bearing flowers once it is in its second year. Generally, however, when the taproot reaches about 1 inch in diameter, it is harvested. This is the time when the root is juicy and tender. Carrots come in different shapes and colors, depending on the types of cultivar. Oriental ones usually have flat upper ends and are long. They also have tail-like lower ends that taper off. The European counterparts come in cylindrical bodies that have rounded ends. These also come in a bright orange color compared to the saffron-colored ones from Asia.

When buying carrots, it is important to look for young ones that are bright-colored and tender. They should also be firm. Avoid buying roots that are very large, as this could indicate that they are already mature, which may make them more difficult to eat.

The Different Health Benefits

It is well-known that carrots are healthy, but what are the benefits that they give to those who eat them? Here’s a rundown of the different health benefits one could gain from eating carrots:

  • Carrots are naturally rich in vitamins, antioxidants and dietary fiber. They only give 41 calories for every 100 grams, with a negligible fat content and no cholesterol.
  • Carrots are also rich in vitamin A and beta-carotenes, which help protect people from developing mouth and lung cancers. These compounds, along with flavonoid compounds, help protect the skin too.
  • Research conducted by the scientists at the University of Newcastle discovered that falcarinol found in carrots may help prevent cancer, as it destroys cells that are pre-cancerous. The study was conducted on laboratory animals.
  • Fresh carrots are also rich in vitamin C, giving about 9% of the RDA. Vitamin C helps keep the gums, teeth and connective tissues healthy. Its antioxidant properties also help the body be protected from various diseases caused by free radicals.
  • The root is also rich in B-complex vitamins, such as vitamin B6, folic acid, thiamine and many more. These are co-factors to certain enzymes that are needed for substrate metabolism.
  • Carotenes are changed by the liver into vitamin A. This vitamin is essential for the maintenance of good vision, sperm production and skin integrity, plus normal growth and development.

Carrots are full of nutrients, which is why people should include these in their diets. These root crops can help people become healthy as well as prevent the onset of various diseases, including cancer. Young and tender carrots are the best ones, as they are sweet and full of various nutrients.

Sources for this article include:

http://myhealthbynature.com

http://www.care2.com

http://www.naturalnews.com

http://science.naturalnews.com

Top Children’s Vitamin Brand Contains Aspartame, GMOs and Other Hazardous Ingredients


The #1 Children’s Vitamin Brand in the US contains ingredients that most parents would never intentionally expose their children to, so why aren’t more opting for healthier alternatives?
Image: rawforbeauty.com

Kids vitamins are supposed to be healthy, right? Well then, what’s going on with Flintstones Vitamins, which proudly claims to be “Pediatricians’ #1 Choice”? Produced by the global pharmaceutical corporation Bayer, this wildly successful brand features a shocking list of unhealthy ingredients, including:

Aspartame

Cupric Oxide

Coal tar artificial coloring agents (FD&C Blue #2, Red #40, Yellow #6)

Zinc Oxide

Sorbitol

Ferrous Fumarate

Hydrogenated Oil (Soybean)

GMO Corn starch

On Bayer Health Science’s Flintstones product page designed for healthcare professionals they lead into the product description with the following tidbit of information:

82% of kids aren’t eating all of their veggies1. Without enough vegetables, kids may not be getting all of the nutrients they need.

References: 1. Lorson BA, Melgar-Quinonez HR, Taylor CA. Correlates of fruit and vegetable intakes in US children. J Am Diet Assoc. 2009;109(3):474-478.

The implication? That Flintstones vitamins somehow fill this nutritional void. But let’s look a little closer at some of these presumably healthy ingredients….

ASPARTAME

Aspartame is a synthetic combination of the amino acids aspartic acid and l-phenylalanine, and is known to convert into highly toxic methanol and formaldehyde in the body. Aspartame has been linked to over 40 adverse health effects in the biomedical literature, and has been shown to exhibit both neurotoxicity and carcinogenicity [1] What business does a chemical like this have doing in a children’s vitamin, especially when non-toxic, non-synthetic non-nutritive sweeteners like stevia already exist?

CUPRIC OXIDE 

Next, let’s look closer at Cupric Oxide, 2mg of which is included in each serving of Flinstone’s Complete chewable vitamins as a presumably ‘nutritional’ source of ‘copper,’ supplying “100% of the Daily Value (Ages 4+), according to Flintstones Vitamins Web site’s Nutritional Info.[2]
But what is Cupric Oxide? A nutrient or a chemical?

According to the European Union’s Dangerous Substance Directive, one of the main EU laws concerning chemical safety, Cupric Oxide is listed as a Hazardous substance, classified as both “Harmful (XN)” and “Dangerous for the environment” (N). Consider that it has industrial applications as a pigment in ceramics, and as a chemical in the production of rayon fabric and dry cell batteries. In may be technically correct to call it a mineral, but should it be listed as a nutrient in a children’s vitamin? We think not.

COAL TAR ARTIFICIAL COLORING AGENTS

Image: rawforbeauty.com


A well-known side effect of using synthetic dyes is attention-deficit hyperactivity disorder. For direct access to study abstracts on this topic view our Food Coloring research page.  There is also indication that the neurotoxicity of artificial food coloring agents increase when combined with aspartame, making the combination of ingredients in Flintstones even more concerning.

ZINC OXIDE

Each serving of Flinstones Complete Chewable vitamins contain 12 mg of zinc oxide, which the manufacturer claims delivers 75% of the Daily Value to children 2  & 3 years of age.  Widely used as a sun protection factor (SPF) in sunscreens, The EU’s Dangerous Substance Directive classifies it as an environmental Hazard, “Dangerous for the environment (N).”  How it can be dangerous to the environment, but not for humans ingesting it, escapes me.  One thing is for sure, if one is to ingest supplemental zinc, or market it for use by children, it makes much more sense using a form that is organically bound (i.e. ‘chelated’) to an amino acid like glycine, as it will be more bioavailable and less toxic.

Sources:  GREENMEDINFO.COM

Vitamins Offer Hope for Alzheimer’s.


Story at-a-glance

  • Alzheimer’s disease is currently at epidemic proportions, with 5.4 million Americans—including one in eight people aged 65 and over—living with it. There is no known cure, and few truly effective treatments
  • Research suggests the best hope is in prevention focusing on diet, exercise and staying mentally active.
  • Two recent studies show that compounds in cinnamon, and vitamins B12, B6, and folate may delay the onset and/or slow progression of the disease
  • Vitamin treatment consisting of 0.8 mg folic acid, 20 mg vitamin B6 and 0.5 mg vitamin B12 slowed shrinkage of the whole brain volume over the course of two years
  • The vitamin treatment also reduced, by as much as seven-fold, the cerebral atrophy in certain brain regions that are particularly vulnerable to damage associated with Alzheimer’s disease
  • Research suggests that being exposed to general anesthesia can increase the risk of dementia in the elderly by as much as 35 percent.
  • cinnamon

In the United States, Alzheimer’s disease is currently at epidemic proportions, with 5.4 million Americans—including one in eight people aged 65 and over—living with the disease, according to the Alzheimer’s Association’s 2011 Alzheimer’s Disease Facts and Figures1.

By 2050, this is expected to jump to 16 million, and in the next 20 years, it is projected that Alzheimer’s will affect one in four Americans, rivaling the current prevalence of obesity and diabetes.

There is still no known cure for this devastating disease, and very few treatments.Alzheimer’s drugs are often of little to no benefit at all, which underscores the importance of prevention throughout your lifetime.

Research repeatedly suggests the best hope for patients lies in prevention through optimal diet, exercise and staying socially and mentally active. As recently reported by Forbes2:

“[A] new study in Science suggested that last year’s ‘breakthrough’ pharmaceutical, bexarotene (Targretin) – a cancer drug that had initially received wide publicity for helping break up the plaques in Alzheimer’s – doesn’t seem to do this very well at all, and can have significant adverse side effects for the patient.

‘Something happened in that initial report – either something technically or otherwise, which we can’t put our hands on at this point in time,” study author Sangram Sisodia told US News & World Report. ‘Something is seriously wrong.’

While memory loss is common among Westerners, it is NOT a “normal” part of aging. Research has shown that even mild “senior moments” are caused by the same brain lesions associated with Alzheimer’s disease and other forms of dementia. These cognitive changes are by no means inevitable!

People who experience very little decline in their cognitive function up until their deaths have been found (post-mortem) to be free of brain lesions, showing that it’sentirely possible to prevent the damage from occurring in the first place. At the end of this article, I share my best tips for maintaining healthy brain function well into old age.

In recent years, researchers studying natural compounds have offered new hope. For example, two recent studies suggest that compounds in cinnamon, as well as vitamins B12, B6, and folate may delay the onset and/or slow progression of the disease.

The Promise of Cinnamon and Vitamins in the Fight Against Alzheimer’s Disease

The first study in question, published in the Journal of Alzheimer’s Disease3,found that cinnamaldehyde and epicatechin, two compounds found in cinnamon, have an inhibitory effect on the aggregation of a particular protein called tau. Tau plays a large role in the structure and function of neurons.

But while a normal part of cell structures, this protein can begin to accumulate, forming “neurofibrillary tangles” that are a hallmark of Alzheimer’s disease. Both compounds were found to protect tau from oxidative damage that can lead to dysfunction.

Donald Graves, adjunct professor in UCSB‘s Department of Molecular, Cellular, and Developmental Biology and co-author of the study explained the protective process to Medical News Today4:

“‘Take, for example, sunburn, a form of oxidative damage. If you wore a hat, you could protect your face and head from the oxidation. In a sense this cinnamaldehyde is like a cap. While it can protect the tau protein by binding to its vulnerable cysteine residues, it can also come off,’ Graves added, which can ensure the proper functioning of the protein.”

It’s interesting to note that there’s a high correlation between type 2 diabetes and Alzheimer’s disease. Some even believe Alzheimer’s may be a form of brain diabetes. Insulin and insulin receptors in your brain are crucial for learning and memory, and it’s known that these components are lower in people with Alzheimer’s disease.

In addition to the above findings, cinnamon has also been found to have beneficial effects on blood glucose management in type 2 diabetics. This is one of the reasons I include cinnamon in my healthy coconut candy recipe.

B Vitamins Again Show Promise in Alzheimer’s Prevention

The other study, published in Proceedings of the National Academy of Sciences5, found that vitamins B6, B12, and folic acid may help slow the progression of the disease, confirming and supporting previous studies. As reported in the featured article6:

“The fact that B-family vitamins may play a significant role in dementia, or more specifically in warding it off has been consistently illustrated. What is news from the current study, however, is that high-dose B-vitamin treatment in people at risk for the disease ‘slowed shrinkage of whole brain volume,’ and especially reduced shrinkage in areas known to be affected in Alzheimer’s disease.”

The 156 study participants, all of whom were over the age of 70, were diagnosed with mild cognitive impairment. This, along with midlife hypertension, midlife obesity and diabetes, is a known risk factor for Alzheimer’s. One group of participants received a placebo while the other received high-dose B-vitamin treatment consisting of:

  • 0.8 mg folic acid
  • 20 mg vitamin B6
  • 0.5 mg vitamin B12

It is important to note that vitamin B12 comes in many forms and it is typically injected because it is not absorbed well by most people, especially in the elderly who need it most. This is due to it being one of the largest vitamins known. The most common form is cyanocobalamin but a better from would be methylcobalamin. A better alternative to B12 injections would also be sublingual sprays, which are absorbed very similarly to the injections.

The treatment effectively slowed shrinkage of the whole brain volume over the course of two years. It also reduced, by as much as seven-fold, the cerebral atrophy in certain brain regions that are particularly vulnerable to damage associated with Alzheimer’s disease. Another major boon: The supplements cost less than 50 cents a day and are readily available in pharmacies and health-food stores. In the placebo group, higher homocysteine levels at baseline were associated with faster atrophy in these same regions. According to the researchers7:

“We… show that the beneficial effect of B vitamins is confined to participants with high homocysteine… and that, in these participants, a causal Bayesian network analysis indicates the following chain of events: B vitamins lower homocysteine, which directly leads to a decrease in gray matter atrophy, thereby slowing cognitive decline.

Our results show that B-vitamin supplementation can slow the atrophy of specific brain regions that are a key component of the AD process and that are associated with cognitive decline.”

Dr. A. David Smith, professor emeritus of pharmacology at Oxford University, founding director of the Oxford Project to Investigate Memory and Ageing, and senior author of the study told Bloomberg News8 that this B-vitamin treatment is “the first and only disease-modifying treatment that’s worked. We have proved the concept that you can modify the disease.” This shouldn’t come as a surprise to anyone who understands that without proper nutrition and exercise, your brain will be increasingly vulnerable to damage with age…

Vitamin B Cocktail Already Used for Dementia Prevention in Sweden

Three years ago, the same group of researchers showed that the atrophy rate in patients’ whole brains was reduced by about 30 percent in those taking the vitamin cocktail9. The atrophy rate was even higher—53 percent—in those who had elevated homocysteine levels, a benefit that was reconfirmed in the featured study. According to Bloomberg10:

“The studies, known as Vitacog, were funded by seven charities and government agencies and vitamin maker Meda AB of Solna, Sweden. Smith is an inventor on three patents held by Oxford University for B vitamin formulations to treat Alzheimer’s disease… Vitamin B12 is found in liver, fish and milk and folic acid in fruit and vegetables. Deficiency of folate and B vitamins is already linked to dementia…

Doctors in Sweden began measuring homocysteine in people who report declining memory about two years ago, said [Johan] Lokk [professor and head physician in the geriatric department at Karolinska University Hospital in Sweden, who wasn’t involved in the study]...

Swedish patients with high homocysteine are given folic acid and B vitamins, even if they aren’t deficient. ‘We think the increased homocysteine level could be deleterious to the brain,’ Lokk said. ‘We wanted to be on the offensive in diagnosing and treating patients. In our opinion, it is harmless and cheap.’”

General Anesthesia Could Increase Risk of Dementia in Elderly by 35 Percent

Related research suggests that being exposed to general anesthesia can increase the risk of dementia in the elderly by as much as 35 percent. The research was presented at the annual congress of the European Society of Anesthesiology (ESA). As reported by Medical News Today11:

“Postoperative cognitive dysfunction, or POCD, could be associated with dementia several years later. POCD is a common complication in elderly patients after major surgery. It has been proposed that there is an association between POCD and the development of dementia due to a common pathological mechanism through the amyloid β peptide. Several experimental studies suggest that some anesthetics could promote inflammation of neural tissues leading to POCD and/or Alzheimer’s disease (AD) precursors including β-amyloid plaques and neurofibrillary tangles.”

Participants aged 65 and over were followed for a total of 10 years. Participants exposed to at least one general anesthetic over the follow-up had a 35 percent increased risk of developing a dementia compared to those who were not exposed to anesthesia. According to lead researcher Dr. Francois Sztark12:

“These results are in favor of an increased risk for dementia several years after general anesthesia. Recognition of POCD is essential in the perioperative management of elderly patients. A long-term follow-up of these patients should be planned.”

Tips for Avoiding Alzheimer’s Disease

The beauty of following my revised Nutrition Plan is that it helps treat and prevent all chronic degenerative diseases, from the common ones like heart disease, diabetes, obesity and Alzheimer’s to the ones you have never heard of or can’t even pronounce. So please read the Plan as soon as you can. It is divided into three helpful sections, Beginner, Intermediate and Advanced to help you start at the right level.

The plan is the first step in addressing Alzheimer’s disease, which is currently at epidemic proportions, with 5.4 million Americans – including one in eight people aged 65 and over – living with the disease.

Remember, while memory loss is indeed common among Westerners, it is NOT a “normal” part of aging, and cognitive changes are by no means inevitable. People who experience very little decline in their cognitive function up until their deaths have been found (post-mortem) to be free of brain lesions, showing that it’s entirely possible to prevent the damage from occurring in the first place… and one of the best ways to do this is by leading a healthy lifestyle.

  • Sugar and Fructose. Ideally, you’ll want to keep your sugar levels to a minimum and your total fructose below 25 grams per day, or as low as 15 grams per day if you have insulin resistance or any related disorders.
  • Improve magnesium levels. There is some exciting preliminary research strongly suggesting a decrease in Alzheimer symptoms with increased levels of magnesium in the brain. Unfortunately, most magnesium supplements do not pass the blood brain levels, but a new one, magnesium threonate, appears to and holds some promise for the future for treating this condition and may be superior to other forms.
  • Optimize your vitamin D levels with safe sun exposure. Strong links between low levels of vitamin D in Alzheimer’s patients and poor outcomes on cognitive tests have been revealed. Researchers believe that optimal vitamin D levels may enhance the amount of important chemicals in your brain and protect brain cells by increasing the effectiveness of the glial cells in nursing damaged neurons back to health.

Vitamin D may also exert some of its beneficial effects on Alzheimer’s through its anti-inflammatory and immune-boosting properties. Sufficient vitamin D is imperative for proper functioning of your immune system to combat inflammation that is also associated with Alzheimer’s.

  • Keep your fasting insulin levels below 3. This is indirectly related to fructose, as it will clearly lead to insulin resistance. However other sugars (sucrose is 50 percent fructose by weight), grains and lack of exercise are also important factors. Lowering insulin will also help lower leptin levels which is another factor for Alzheimer’s.
  • Vitamin B12: In addition to the research presented above, a small Finnish study published in the journal Neurology13 also found that people who consume foods rich in B12 may reduce their risk of Alzheimer’s in their later years. For each unit increase in the marker of vitamin B12, the risk of developing Alzheimer’s was reduced by two percent. Remember sublingual methylcobalamin may be your best bet here.
  • Eat a nutritious diet, rich in folate, such as the one described in my nutrition plan. Vegetables, without question, are your best form of folate, and we should all eat plenty of fresh raw veggies every day. Avoid supplements with folic acid, which is the inferior synthetic version of folate.
  • High-quality animal-based omega-3 fats, such as krill oil. (I recommend avoiding most fish because, although fish is naturally high in omega-3, most fish are now severely contaminated with mercury.) High intake of the omega-3 fats EPA and DHA help by preventing cell damage caused by Alzheimer’s disease, thereby slowing down its progression, and lowering your risk of developing the disorder.
  • Avoid and eliminate mercury from your body. Dental amalgam fillings, which are 50 percent mercury by weight, are one of the major sources of heavy metal toxicity. However you should be healthy prior to having them removed. Once you have adjusted to following the diet described in my optimized nutrition plan, you can follow the mercury detox protocol and then find a biological dentist to have your amalgams removed.
  • Avoid aluminum, such as antiperspirants, non-stick cookware, vaccine adjuvants, etc.
  • Exercise regularly. It’s been suggested that exercise can trigger a change in the way the amyloid precursor protein is metabolized14, thus, slowing down the onset and progression of Alzheimer’s. Exercise also increases levels of the protein PGC-1alpha. Research has also shown that people with Alzheimer’s have less PGC-1alpha in their brains11 and cells that contain more of the protein produce less of the toxic amyloid protein associated with Alzheimer’s. I would strongly recommend reviewing the Peak Fitness Technique for my specific recommendations.
  • Avoid flu vaccinations as most contain both mercury and aluminum, well-known neurotoxic and immunotoxic agents.
  • Eat blueberries. Wild blueberries, which have high anthocyanin and antioxidant content, are known to guard against Alzheimer’s and other neurological diseases. Like any fruit though, avoid excesses here.
  • Challenge your mind daily. Mental stimulation, especially learning something new, such as learning to play an instrument or a new language, is associated with a decreased risk of Alzheimer’s. Researchers suspect that mental challenge helps to build up your brain, making it less susceptible to the lesions associated with Alzheimer’s disease.
  • Avoid anticholinergic and statin drugs. Drugs that block acetylcholine, a nervous system neurotransmitter, have been shown to increase your risk of dementia. These drugs include certain nighttime pain relievers, antihistamines, sleep aids, certain antidepressants, medications to control incontinence, and certain narcotic pain relievers.

Statin drugs are particularly problematic because they suppress the synthesis of cholesterol, deplete your brain of coenzyme Q10 and neurotransmitter precursors, and prevent adequate delivery of essential fatty acids and fat-soluble antioxidants to your brain by inhibiting the production of the indispensable carrier biomolecule known as low-density lipoprotein.

Other Natural Treatments for Your Anti-Alzheimer’s Arsenal

Finally, there are a few other nutritional recommendations worth noting for their specific benefits in preventing and treating dementia. So, although your fundamental strategy for preventing dementia should involve a comprehensive lifestyle approach, you may want to consider adding a few of these natural dietary agents to your anti-Alzheimer’s arsenal. These four natural foods/supplements have good science behind them, in terms of preventing age-related cognitive changes:

  1. Coconut Oil: The primary fuel your brain needs for energy is glucose. However, your brain is able to run on more than a single type of fuel, one being ketones (ketone bodies), or ketoacids. Ketones are what your body produces when it convertsfat (as opposed to glucose) into energy.

The medium-chain triglycerides (MCT) found in coconut oil are GREAT source of ketone bodies, because coconut oil is about 66 percent MCTs. In fact, ketones appear to be the preferred source of brain food in patients affected by diabetes or Alzheimer’s.

  1. Astaxanthin is a natural pigment with unique properties and many clinical benefits, including some of the most potent antioxidant activity currently known. As a fat-soluble nutrient, astaxanthin readily crosses your blood-brain barrier. One study15 found it may help prevent neurodegeneration associated with oxidative stress, as well as make a potent natural “brain food.”

The molecules of astaxanthin neutralize free radicals and other oxidants without being destroyed or becoming pro-oxidants themselves in the process. It’s is a unique molecule whose shape allows it to precisely fit into a cell membrane and span its entire width. In this position, astaxanthin can intercept potentially damaging molecules before they can damage your cells.

You can get some astaxanthin by taking krill oil, which is a fantastic omega-3 fat supplement. But you can boost your astaxanthin even MORE by adding a pure astaxanthin supplement to your nutritional regimen. For optimal absorption, make sure to take krill oil and/or astaxanthin with a fat-containing meal, since both are fat-soluble.

  1. Gingko biloba: Many scientific studies have found that Gingko biloba has positive effects for dementia. Gingko, which is derived from a tree native to Asia, has long been used medicinally in China and other countries. A 1997 study from JAMAshowed clear evidence that Gingko improves cognitive performance and social functioning for those suffering from dementia.

Research since then has been equally promising. One study in 2006 found Gingko as effective as the dementia drug Aricept (donepezil) for treating mild to moderate Alzheimer’s type dementia. A 2010 meta-analysis found Gingko biloba to be effective for a variety of types of dementia.

  1. Alpha lipoic acid (ALA): ALA can stabilize cognitive functions among Alzheimer’s patients and may slow the progression of the disease.

Source: mercola.com

 

 

Vitamin D and breast cancer: Emerging concepts.


Vitamin D and a few of the analogs have been studied for cancer chemoprevention and therapy. ► Vitamin D protects against stress induced cell death whereas suppresses cell proliferation of cancer cells. ► VDR Fok1 polymorphism can be used as a risk factor or for predicting response to vitamin D. ► Vitamin D regulates constitutive splicing of its target gene CYP24A1. ► Regulation of expression of certain microRNA by vitamin D can be used as useful markers for vitamin D responsiveness.

Abstract

The benefit of vitamin D in cancer prevention and to certain extent therapy has been well recognized. The active form of vitamin D, 1,25-dihydroxycholecalciferol (1,25(OH)2 D3) is a natural ligand for vitamin D receptor (VDR). Since 1,25(OH)2D3 exerts toxic effects at a concentration that is beneficial, nearly 1500 analogs of vitamin D have been synthesized and evaluated for their efficacy in a variety of carcinogenesis and human cancer models both in vitro and in vivo. Among these only a handful of them have been approved for evaluation in clinical trials for leukemia, breast, prostate and colon cancers. The mechanism of vitamin D action is mediated by the nuclear VDR and the signaling cascade for its action is extensively reported. In this review we focus on the newer concepts for vitamin D action. These include (1) differential effects of vitamin D in maintaining cell proliferation when the cells are under stress but suppressing cell growth when the cells are transformed; (2) functional significance of VDR polymorphism in potential vitamin D responsiveness; (3) regulation of constitutive splicing of vitamin D target gene, CYP24a, by the hormone and its significance; and (4) regulation of microRNA by vitamin D in breast cancer. It is anticipated that the new work in these selective areas would expand the understanding of vitamin D in breast cancer prevention and therapy.

Source: cancer letters

 

 

 

 

Avocado Health Benefits: The World’s Most Perfect Food?


avocado-xavocado-and-leaves

Did you know that the avocado has been called the world’s most perfect food and has many health benefits?

It has achieved this distinction because many nutritionists claim it not only contains everything a person needs to survive — but it has also been found to contribute to the prevention and control of Alzheimer’s, cancer, heart disease, diabetes and other health conditions.

The avocado (Persea gratissima or P. americana) originated in Puebla, Mexico and its earliest use dates back to 10,000 years B.C. Since AD 900, the avocado tree has been cultivated and grown in Central and South America. In the 19th century, the avocado made its entry into California, and has since become a very successful commercial crop. Ninety-five percent (95%) of U.S. avocados are gown in Southern California.

The avocado, also called the alligator pear, is a high-fiber, sodium- and cholesterol-free food that provides nearly 20 essential nutrients, including fiber, is rich in healthy monounsaturated and polyunsaturated fats (such as omega-3 fatty acids), vitamins A, C, D, E, K and the B vitamins (thiamine, riboflavin, niacin, pantothenic acid, biotin, vitamin B-6, vitamin B-12 and folate) — as well as potassium.

Foods naturally rich in omega-3 fatty acids, such as avocados, are widely acknowledged as the secret to a healthy heart, a brilliant brain and eagle eyes.

Dr. Daniel G. Amen, a clinical neuroscientist, psychiatrist, brain-imaging expert and author of the New York Times bestseller Change Your Brain, Change Your Life counts avocados as one of the top brain-healthy foods that can help prevent Alzheimer’s Disease.

That’s not only because of the avocado’s health benefits omega-3 fatty acid content but also its…

Vitamin E content — An international journal called Alzheimer’s Disease and Associated Disorders, reported its findings from years of clinical trials — high doses of Vitamin E can neutralize free radicals and the buildup of proteins to reverse the memory loss in Alzheimer’s patients; reverse symptoms of Alzheimer’s in the early stages and retard the progression of the disease;

Folate content — helps to prevent the formation of tangled nerve fibers associated with Alzheimer’s.

The virtues and benefits of the avocado are too numerous to mention.

But Here Are Just a Few More Avocado Health Benefits That Its Nutritional Profile Provides:
  • Monounsaturated Fats — These types of fats help control triglycerides in the bloodstream, lower blood cholesterol and control diabetes.
  • Folate — This water-soluble B vitamin promotes healthy cell and tissue development. According to the National Institute of Health’s Office of Dietary Supplements, “This is especially important during periods of rapid cell division and growth such as infancy and pregnancy. Folate is also essential for metabolism of homocysteine and helps maintain normal levels of this amino acid.”
  • Lutein — This is a carotenoid (a natural pigment) that protects against cataracts and certain types of cancer, and reduces the risk of macular degeneration, the leading cause of blindness in adults 65 years of age and older. Avocados contain 3 or more times as much lutein as found in other common vegetables and fruits.
  • Oleic acid and Potassium — Both of these nutrients also help in lowering cholesterol and reducing the risk of high blood pressure.
You can add these avocado benefits to your diet in many ways:
  1. The easiest way is to cut the avocado in half and sprinkle it with herbal seasoning or maple syrup.
  2. Chop the avocado and add it to a salad, or use it as a topping or side garnish for soup.
  3. Mash an avocado and spread it on bread or a bagel (in place of butter or cream cheese).
  4. Cut an avocado in half and fill the little hollow (left after you remove the pit) with your favorite healthy topping such as herbed rice or couscous.
  5. Make an avocado dressing or the crowd-pleasing guacamole dip to add flavor to raw or steamed vegetables. You can easily find many avocado recipes online.

Blended with fruit, avocados make a rich and delicious snack, side dish or dessert — and produces highly-nutritious baby food which delivers “good fat” for baby’s brain and physical development.

Before you indulge in avocados to your heart’s content, however, remember that they have lots of calories because of their fat content. According to WebMD, “A medium-sized avocado contains 30 grams of fat, as much as a quarter-pound burger”.

That’s why diet experts have long urged Americans to go easy on avocados in favor of less fatty fruits and vegetables. But now nutritionists are taking another look.

They’re finding that most of the fat in an avocado is monounsaturated — the “good” kind that actually lowers cholesterol levels. Thanks to this new understanding, the U.S. government recently revised its official nutrition guidelines to urge Americans to eat more avocados.

Source: http://csglobe.com