Groundbreaking study reveals that heart disease is an early indicator of vitamin C deficiency


Image: Groundbreaking study reveals that heart disease is an early indicator of vitamin C deficiency

Heart disease is usually linked to issues with cholesterol, but researchers are increasingly finding that vitamin C plays an outsized role in heart health. This antioxidant nutrient, which the body uses to make connective tissue, has already gotten some buzz for its utility in cancer treatment, but its effects on the heart may be even greater.

Researchers at the Dr. Rath Research Institute of California found that a vitamin C deficiency can cause coronary heart disease. In their study, they used transgenic mice that mimic the human metabolism in two key ways: They don’t produce vitamin C internally, and they generate lipoprotein to make up for this. After feeding the mice a diet that was lacking in vitamin C, their bodies acted as expected and created their own lipoprotein to fix the vascular walls. This caused them to develop heart issues and atherosclerosis.

Crucially, they discovered that the degree and level of heart disease the mice developed was directly linked to their vitamin C intake and blood levels. Those mice who had consumed the highest amounts of vitamin C naturally produced the least lipoprotein to repair their arteries, and by extension, had the strongest hearts and fewest atherosclerotic lesions.

Therefore, the researchers believe that proper vitamin C intake could be the secret to preventing heart disease and other cardiovascular problems. That doesn’t mean that cholesterol isn’t important; maintaining healthy HDL and LDL cholesterol levels is still a powerful component of overall health, but it may not play as big of a role as once believed.

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Higher vitamin C intake linked to lower heart disease risk

This is supported by a study that was recently published in the Journal of the American College of Nutrition. That study looked at 108 men and divided them into three groups according to their intake of vitamin C.

They found that the men in the top tier of vitamin C intake had a 66 percent lower risk of heart disease compared to those who had the lowest intake. The researchers aren’t sure exactly how vitamin C brings about such significant benefits to heart health. They theorize that it could be related to its ability to prevent and ease the stiffening in artery walls that can block the flow of blood. In fact, they discovered that the vitamin is especially effective at doing this in people who smoke.

Further studies provide additional evidence of vitamin C’s heart benefits. For example, a study carried out by the University of Copenhagen that involved more than 100,000 people found that higher blood concentrations of vitamin C were associated with a lower risk of not only cardiovascular disease but also death. It is important to keep in mind, however, that they saw this benefit in those whose high vitamin C blood levels came from eating lots of vegetables and fruits.

Getting vitamin C from food is preferable

The researchers said that although vitamin C supplements can help raise your levels of this important nutrient, getting it from a healthy diet is far preferable. Doing so will also help you develop a long-term healthy lifestyle, which will bring many other health benefits over time.

With heart disease being the leading cause of death around the world, we are lucky to have such an affordable way to prevent it that has very few side effects. Some of the best food sources of vitamin C include citrus fruits, acerola cherries, kale, broccoli, kiwis, strawberries, sweet potatoes, and bell peppers. Best of all, eating these foods will not just enhance your heart health; your immunity will also get a nice boost!

Sources for this article include:

NaturalHealth365.com

NaturalNews.com

‘Healthier’ Fast Food Options for Kids May Not Be


Promises of healthier kids’ meals have drawn increasing numbers of families back to fast food restaurants, but most kids are still being served unhealthy options, a new survey finds.

Nine out of 10 parents had purchased lunch or dinner for their child in the past week at one of the big four fast food chains in 2016, up from 8 of 10 parents in 2010, the results showed.

This increase was driven in part by fast food claims that they’ve replaced sugary sodas and greasy french fries with healthier options in kids’ meals, said lead researcher Jennifer Harris, director of marketing initiatives for the University of Connecticut’s Rudd Center for Food Policy and Obesity.

But children are still dining on kids’ meals full of fat, sodium and calories, with no sign that the healthier options are making much of a difference, Harris added.

“It’s a marketing tactic on the part of these restaurants to make parents think their products are healthy,” Harris said. “If they can make parents think it’s actually a healthy choice to take their child there, then it’s good for their business. That’s what we found, even though what kids are getting really hasn’t changed.”

Since 2013, the four largest fast food restaurant chains — McDonald’s, Burger King, Wendy’s and Subway — have introduced policies to offer healthier drinks and sides with their kids’ meals, Harris said.

To see whether these policies have made a difference, the Rudd Center conducted an online survey with approximately 800 parents regarding lunch or dinner purchases at one of the big four chains.

Published Sept. 27, the Rudd survey found that 74 percent of kids still receive unhealthy drinks or side items with their kids’ meals when they eat fast food:

  • Only 6 out of 10 parents who purchased a kids’ meal received a healthier drink such as low-fat milk or fruit juice, indicating no change between 2010 and 2016.
  • Two-thirds of parents chose a healthier drink for a preschool-age child (2-5), on average, but only half chose a healthier drink for an older child (6-11).
  • Half of parents received a healthier side with a kids’ meal in 2016, such as yogurt or apple slices. However, 6 out of 10 received an unhealthy side like french fries or chips, since some restaurants now offer two sides with kids’ meals.
The healthy-option policies have made a difference in one critical way, however.

Nearly all of the parents said they plan to purchase fast food for their child more often because of restaurants’ healthier kids’ meal policies, researchers found.

“When you ask parents about that, they think it’s great that kids’ meals are healthier now,” Harris said. “But there really hasn’t been any change.”

About one-third of parents didn’t even bother with a kids’ meal for their children. They purchased regular menu items, which include adult-sized portions and tend to be less nutritious than kids’ meal items.

The Rudd Center argues that policymakers should follow the lead of communities in California, Colorado, Kentucky and Maryland, where laws or regulations have been adopted to require that all restaurants automatically provide healthy drinks and sides with kids’ meals.

Restaurants can help by promoting healthier choices and discontinuing the practice of offering unhealthy sides alongside healthier sides, the Rudd Center added.

But parents also need to step up, said registered dietitian nutritionist Malina Linkas Malkani, a spokeswoman for the Academy of Nutrition and Dietetics.

“Until there is more widely enacted legislation that requires the restaurants to automatically offer these healthy choices, the responsibility falls pretty squarely on parents and caregivers to make the healthier choices and to teach their children how to make those choices for themselves,” Malkani said.

Parents should teach kids to avoid foods heavy in added sugars, sodium and saturated fat, Malkani said. They also should promote foods rich in protein, calcium, vitamin D, iron, healthy fats and vitamin C.

Malkani said it was “disheartening to hear the high percentage of children who received the less healthy beverages and sides, but I did think it was good news that there are healthier beverages and sides available.

“I have to give so much credit to the chains that are offering the healthier choices automatically. I hope this is a trend that takes off,” she said.

High doses of vitamin C aggressively kill cancer cells, research confirms


 

Image: High doses of vitamin C aggressively kill cancer cells, research confirms

If you’ve heard that high doses of vitamin C can kill cancer, there’s a good chance you’ve also heard some official-sounding organizations claiming that there is no science to back this up. However, new research shows that high doses of vitamin C can indeed fight cancer, underscoring the findings of countless other studies like it that are widely ignored by the medical industry.

Detractors choose to focus on those studies that showed it didn’t work, conveniently ignoring the fact that many of the studies that were inconclusive in this regard simply weren’t testing big enough doses to unlock its effectiveness.

Research carried out at the University of Iowa confirms that vitamin C does kill cancer cells selectively without damaging normal cells. One study showed that the vitamins can reduce mutations that cause cancer in mice, while another study showed it can kill as much as 50 percent of human lymphoma cells.

Another study, this one from the Perlmutter Cancer Center, found that injecting mice with high doses of vitamin C stopped leukemia cancer stem cells from humans from growing, probably by telling the faulty stem cells in bone marrow to die. A different study found that adding vitamin C via IV to typical chemotherapy drugs extended the average survival times of pancreatic cancer patients from 5.65 months to 12 months.

Then there’s the University of Kansas study that injected high doses of vitamin C into ovarian cells from humans. They found that the vitamin targeted the ovarian cancer cells without harming healthy cells, and they went on to repeat the study on mice and human subjects.

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These findings wouldn’t be surprising to the researchers who worked on a review that was published in the Puerto Rico Health Sciences Journal in 2008. After looking at studies that used extremely higher amounts of vitamin C intravenously, they concluded that it can be effective against tumors, although they said that its efficacy could not be judged when it was administered orally.

Even though the authors called for further research into vitamin C’s cancer-fighting power, nothing was done about it at the time. After all, chemotherapy has been so profitable for the medical and pharmaceutical industries, and it would be hard to profit off of something as cheap, widely available, and unpatentable as vitamin C .

IV may not be the only way to deliver high doses of vitamin C

Some people have been getting these treatments on their own at alternative cancer clinics, but it’s not widely accepted. In addition, those who are wary of IVs find it extremely difficult to get the high blood concentration needed for this treatment to work its magic when they take it orally.

Now, however, there is a new form of vitamin C that could change everything. Liposomal vitamin C can create vitamin C levels in the blood that are 100 to 500 times greater than those normally achieved by oral ingestion, making it easier for people to fight cancer.

Liposomal vitamin C is encapsulated in lecithin, which shields it from digestive enzymes that would normally break it down. It makes its way through the digestive system with ease and is absorbed by the intestines before being transported into the liver, where it is released into the bloodstream.

This approach does away with the waste and gastric upset seen with conventional vitamin C tablets while maintaining high blood concentrations. Whether it will one day make its way into the mainstream and give riskier treatments like chemotherapy a run for their money remains to be seen, however.

Sources for this article include:

NaturalHealth365.com

NaturalNews.com

NaturalNews.com

Tuberculosis drugs work better with vitamin C


https://speciality.medicaldialogues.in/tuberculosis-drugs-work-better-with-vitamin-c/

Vitamin C kills tumor cells with hard-to-treat mutation


PET scans reveal glucose-hungry tumors (here lung masses) that may be susceptible to vitamin C therapy.

PET scans reveal glucose-hungry tumors (here lung masses) that may be susceptible to vitamin C therapy.

Maybe Linus Pauling was on to something after all. Decades ago the Nobel Prize–winning chemist was relegated to the fringes of medicine after championing the idea that vitamin C could combat a host of illnesses, including cancer. Now, a study published online today in Science reports that vitamin C can kill tumor cells that carry a common cancer-causing mutation and—in mice—can curb the growth of tumors with the mutation.

If the findings hold up in people, researchers may have found a way to treat a large swath of tumors that has lacked effective drugs. “This [could] be one answer to the question everybody’s striving for,” says molecular biologist Channing Der of the University of North Carolina, Chapel Hill, one of many researchers trying to target cancers with the mutation. The study is also gratifying for the handful of researchers pursuing vitamin C, or ascorbic acid, as a cancer drug. “I’m encouraged. Maybe people will finally pay attention,” says vitamin C researcher Mark Levine of the National Institute of Diabetes and Digestive and Kidney Diseases.

In 1971, Pauling began collaborating with a Scottish physician who had reported success treating cancer patients with vitamin C. But the failure of two clinical trials of vitamin C pills, conducted in the late 1970s and early 1980s at the Mayo Clinic in Rochester, Minnesota, dampened enthusiasm for Pauling’s idea. Studies by Levine’s group later suggested that the vitamin must be given intravenously to reach doses high enough to kill cancer cells. A few small trials in the past 5 years—for pancreatic and ovarian cancer—hinted that IV vitamin C treatment combined with chemotherapy can extend cancer survival. But doubters were not swayed. “The atmosphere was poisoned” by the earlier failures, Levine says.

A few years ago, Jihye Yun, then a graduate student at Johns Hopkins University in Baltimore, Maryland, found that colon cancer cells whose growth is driven by mutations in the gene KRASor a less commonly mutated gene, BRAFmake unusually large amounts of a protein that transports glucose across the cell membrane. The transporter, GLUT1, supplies the cells with the high levels of glucose they need to survive. GLUT1 also transports the oxidized form of vitamin C, dehydroascorbic acid (DHA), into the cell, bad news for cancer cells, because Yun found that DHA can deplete a cell’s supply of a chemical that sops up free radicals. Because free radicals can harm a cell in various ways, the finding suggested “a vulnerability” if the cells were flooded with DHA, says Lewis Cantley at Weill Cornell Medicine in New York City, where Yun is now a postdoc.

Cantley’s lab and collaborators found that large doses of vitamin C did indeed kill cultured colon cancer cells with BRAF or KRAS mutations by raising free radical levels, which in turn inactivate an enzyme needed to metabolize glucose, depriving the cells of energy. Then they gave daily high dose injections—equivalent to a person eating 300 oranges—to mice engineered to develop KRAS-driven colon tumors. The mice developed fewer and smaller colon tumors compared with control mice.

Cantley hopes to soon start clinical trials that will select cancer patients based on KRAS or BRAFmutations and possibly GLUT1 status. His group’s new study “tells you who should get the drug and who shouldn’t,” he says. Cancer geneticist Bert Vogelstein of Johns Hopkins University, in whose lab Yun noticed the GLUT1 connection, is excited about vitamin C therapy, not only as a possible treatment for KRAS-mutated colon tumors, which make up about 40% of all colon cancers, but also for pancreatic cancer, a typically lethal cancer driven by KRAS. “No KRAS-targeted therapeutics have emerged despite decades of effort and hundreds of millions of dollars [spent] by both industry and academia,” Vogelstein says.

Others caution that the effects seen in mice may not hold up in humans. But because high dose vitamin C is already known to be safe, says cancer researcher Vuk Stambolic of the University of Toronto in Canada, oncologists “can quickly move forward in the clinic.”

One drawback is that patients will have to come into a clinic for vitamin C infusions, ideally every few days for months, because vitamin C seems to take that long to kill cancer cells, Levine notes. But Cantley says it may be possible to make an oral formulation that reaches high doses in the blood—which may be one way to get companies interested in sponsoring trials.

Research Proving Vitamin C’s Therapeutic Value in 200+ Diseases


Vitamin C is generally considered to be an important “nutrient,” but its perceived value usually ends there. Only rarely does the public (and the medical profession) glimpse its true potential in the prevention and treatment of disease — and this because, by legal definition (in the US), only FDA-approved drugs can prevent, treat and cure disease.

This does not mean, however, that essential nutrients like Vitamin C cannot in fact prevent and treat disease, i.e. only because it is illegal to speak truthfully about something, doesn’t mean that that something isn’t true.  The National Library of Medicine, in fact, contains thousands of studies demonstrating vitamin C‘s ability to significantly improve health, with 220 disease applications documented on the research site alone.  The best thing ‘we the people’ can do, despite our lack of medical degrees and licensure, and without the FDA’s iron-fisted legal and regulatory apparatus on our side, is to use the peer-reviewed research at our disposal to inform and protect our treatment decisions.

Perhaps we must revisit an important moment in history to regain a sense of how profoundly vitamin C deficiency and vitamin C therapy can affect health. James Lind (1716-1794), pioneer of naval hygiene in the British Royal Navy, conducted the first ever clinical trial proving that citrus fruits cured scurvy. Lind’s discovery saved tens of thousands of seamen from the ravages of scurvy, spurring England’s naval supremacy, putatively changing the course of world history.

If significant historical events like these don’t provide enough evidence to vindicate the efficacy of nutrients like Vitamin C, molecular biology and the science of genetics can help to fill in the gaps.

It is a little known and under-appreciated fact that all humans are born with a serious, life-threatening genetic defect: namely, the inability to manufacture Vitamin C.

This defect occurred approximately 63 million years ago, when our haplorrhini (“simple nosed”) primate predecessors lost the gene (Gulnolactone oxidase pseudogene – GULOP), responsible for the manufacture of Vitamin C from glucose.

The ability to synthesize Vitamin C, in fact, has been lost several times in vertebrates, e.g. in guinea pigs, some bats, some fishes, passeriform birds and in primates of the suborder Haplorrhini, which includes monkes, apes and humans.

It was Linus Pauling, two time Nobel Laureate, and the world’s foremost vitamin C proponent, who first brought this inborn error of metabolism to popular light. Pauling advocated taking large doses of Vitamin C (up to 10-12 grams a day) in order to offset the deficiencies of our modern diet. He believed that it was our movement away from a vitamin C rich fruit-and-vegetable based diet that explained the modern epidemic of heart disease.

According to this perspective, without adequate Vitamin C we are unable to produce the collagen necessary to heal our arteries. The Vitamin C starved body compensates for this by increasing the production of a very small and sticky type of cholesterol known as lipoprotein A, which leads to the formation of atheromatous plaque (clogged arteries). Linus Pauling advocated taking large amounts of vitamin C in combination with the amino acid lysine to reverse the damage done to the arteries, and to prevent recurrence.*

Indeed, a study published in 2008 showed that higher plasma vitamin C levels are associated with a significantly reduced risk of stroke. Scientists from the clinical gerontology unit at Addnbrooke’s University Hospital in Cambridge, UK, tracked 20,649 men and women aged 40 to 79 years, between 1993 and 1997. The group was followed through March 2005. Individuals who had the highest vitamin C levels showed a 42% reduction in stroke risk! If you compare this with Plavix’s 8.7 – 9.4% risk reduction, and the profound side effects drugs like these generate, one begins to understand why the media projection of “vitamins are toxic” propaganda serves only the interests of the drug companies.

Before one goes out and buys a bargain bottle of Vitamin C tablets, one should be advised that ascorbic acid is not exactly the same thing as Vitamin C. Ascorbic acid is found within the Vitamin C complex as it exists in food, but is complexed with a wide range of inseparable cofactors, such as rutin, bioflavonoids (vitamin p), protein chaperones, and various enzymes like tyrosinase, which together in their entirety constitute the whole food complex. Take the ‘vitamin c’ as isolated ascorbic acid out of the nutritional context of food and is behaves more like a chemical or drug.

Ascorbic acid is also 10 times more acidic than the naturally buffered Vitamin C found in raw food, and will on occasions lead to stomach upset, calcium loss from the bones, and kidney stones, in susceptible individuals. Traditionally ascorbic acid is produced semi-synthetically from corn or rice starch through a heavily chemical dependent process. Ascorbic acid can be considered no more natural than white flour, and yet despite this fact, has very little toxicity relative to pharmaceuticals, and can be used in much higher doses than the FDA’s Recommended Daily Allowance without adverse side effects.

The difference between ascorbic acid and Vitamin C in whole food form was perfectly clear to Szent-Gyorgi who received a Nobel Prize in 1937 for discovering Vitamin C. Even though Szent-Gyorgi received international recognition for identifying ascorbic acid as Vitamin C, his later research lead him to conclude that ascorbic acid had very little anti-scurvy activity in and of itself. Szent-Gyorgi found that the vitamin C found in organ meats and food sources like paprika, where the aforementioned cofactors are intact, were far superior in combating scurvy.

We would be well served to acknowledge that all raw fruits and vegetables contain a “life force” that can not be fully decomposed or reduced to the chemical skeleton within which the life force of “vitamin activity” works, no more than our life/soul can be reduced to the $10 or so worth of chemical building blocks that our body is composed of. Fortunately, there are vitamin manufacturers out there who acknowledge this fact, and produce raw whole food concentrates rich in vitamin activity. When eating raw, organic fruits and vegetables is not an option, or when higher levels are needed, these supplements offer authentic therapeutic activity.

The history of vitamin C illustrates just how profoundly important it is for us to get these vital nutrients known as “vitamins,” and that they are best derived from food. If we choose to overlook the importance of vitamins in maintaining health, and yes, even preventing and reversing disease, we will be forced to accept a pharmaceutically driven medical perspective that believes that health is the absence of symptoms, and that symptoms are to be combated or driven back deep into our bodies with sublethal dosages of toxic chemicals, i.e. drugs. Such a perspective on disease is itself so diseased that there is no escaping the ill health that results from it. We must remember that there has never been a disease that has been caused by a lack of a drug… therefore, why would it ever be considered sound medical practice to treat disease with drugs, as a first line of treatment?

*If Linus Pauling and other Vitamin C researchers are correct and a deficiency of Vitamin C causes the breakdown of collagen in the artery, aspirin therapy, which causes Vitamin C deficiency, would not be considered a safe way to reduce cardiac mortality. To the contrary, it would further destabilize the strength and elasticity of the artery leading to hemorrhage, which is the primary deadly side effect of aspirin therapy.

Vitamin C May Be a Potent Adjunct to Cancer Treatment



Story at-a-glance

  • Research shows vitamin C is selectively cytotoxic to cancer cells when administered intravenously in high doses, and has a number of heart and cardiovascular benefits
  • When given intravenously at high doses, vitamin C produces a pro-oxidant effect, thereby generating hydrogen peroxide, which is ultimately what kills the cancer cells
  • Normal tissues are not harmed by the high levels of hydrogen peroxide generated because healthy cells have several ways of effectively removing it, thereby preventing buildup to toxic levels. Cancer cells lack this ability

Vitamin C is one of the most well-established traditional antioxidants known and its potent health benefits have been clearly demonstrated over time — especially for the prevention and treatment of infectious diseases.

Research has also shown that vitamin C is selectively cytotoxic to cancer cells when administered intravenously (IV) in high doses, and has a number of heart- and cardiovascular benefits.

From my perspective, vitamin C is a very useful supplement that should be part of most cancer treatment protocols. Vitamin D is another crucial anti-cancer component I’ve written about on numerous occasions.

How Vitamin C Kills Cancer Cells

In order for vitamin C to effectively kill cancer cells, you need to have a very high concentration of vitamin C in your blood, and the only way to obtain these extreme levels is through IV administration, although using oral liposomal vitamin C can approach effectiveness at a fraction of the price, improved convenience and cost.

By bypassing the digestive tract, IV administration results in blood levels up to 500 times higher than what you can achieve through the oral route.

The mechanism behind vitamin C’s ability to selectively target cancer cells has to do with the generation of hydrogen peroxide, which is ultimately what kills the cancer cells. As reported by the University of Iowa:1

“In a new study2,3 … Buettner and his colleagues have homed in on the biological details of how high-dose vitamin C kills cancer cells. The study shows that vitamin C breaks down easily, generating hydrogen peroxide, a so-called reactive oxygen species that can damage tissue and DNA.

The study also shows that tumor cells are much less capable of removing the damaging hydrogen peroxide than normal cells …

‘Thus, cancer cells are much more prone to damage and death from a high amount of hydrogen peroxide,’ says Buettner, a professor of radiation oncology and a member of Holden Comprehensive Cancer Center at the University of Iowa.

‘This explains how the very, very high levels of vitamin C used in our clinical trials do not affect normal tissue, but can be damaging to tumor tissue.’”

The reason normal tissues are not harmed by the high levels of hydrogen peroxide generated is that healthy cells have several ways of effectively removing it, thereby preventing buildup to toxic levels.

One of the primary pathways of removal is the enzyme catalase, and the study found that cells with reduced catalase activity were indeed more prone to die when exposed to high amounts of vitamin C.

This provides a hint at which cancers are likely the best candidates for high-dose vitamin C therapy — tumors with low catalase levels are likely to be the most responsive, whereas tumors with high catalase levels would be the least responsive. Next, the research team wants to develop methods to measure catalase in tumors.

Vitamin C Lowers Inflammation in Cancer Patients, and More

Another way vitamin C benefits cancer is by lowering inflammation in your body, as shown in a 2012 study.4,5,6

As a general rule, chronic inflammation is a hallmark of cancer, and here they found that IV vitamin C treatment helps lower pro-inflammatory cytokines and C-reactive protein — two inflammatory markers — and that these improvements correlate with a reduction in tumor size.

It also helps lower the risk of metastasis. A positive response was noted in 75 percent of patients. This study was done by scientist at the Riordan Clinic, which is the successor to Linus Pauling and his work on vitamin C. There is likely no clinic in the world with as much experience with vitamin C as the Riordan Clinic.

Riordan carried out a 15-year-long research project called RECNAC (cancer spelled backwards), which showed vitamin C was selectively cytotoxic against cancer cells.

Other research7,8 done by scientists at the Lewis Cantley of Weill Cornel Medicine in New York found high doses of vitamin C helps kill and eliminate colorectal cancer cells with certain genetic mutations. Other studies9 have shown high-dose vitamin C can help slow the growth of prostate-, pancreatic-, liver- and colon cancer cells.

Human studies also show IV vitamin C can help improve symptoms associated with cancer and cancer treatment, such as fatigue, nausea, vomiting, pain and loss of appetite, and improve overall quality of life.

Vitamin C for Infectious Diseases

Vitamin C may be best known for its ability to combat infectious disease. Dr. Thomas Levy’s book, “Curing the Incurable,” details these benefits.

A perfect real-world example is the dramatic case of Allan Smith, who contracted a serious case of swine flu and was brought back from the brink of death using a combination of IV and oral vitamin C.

The case report was sent to me by Levy, who noted that, to his knowledge, vitamin C “has never failed to cure an acute viral syndrome.” According to Albert Szent-Gyorgyi (who won the Nobel Prize in 1937 for his discovery of vitamin C), “health” occurs when there is an ample flow and interchange of electrons in your cells.

Impaired or poor electron flow and interchange equals “disease,” and when the flow and interchange ceases entirely, your cells die. Oxidation, caused by free radicals in your body, involves the loss of electrons.

Antioxidants, both from your diet and endogenously produced, counter the disease process caused by oxidation (loss of electrons) by supplying electrons. Vitamin C is a major antioxidant, and according to Levy, perhaps the most important electron donor to maintain optimal electron flow in your cells.

In 2005, the Orthomolecular Medicine News Service (a non-profit and non-commercial informational resource), published findings that vitamin C is an effective treatment against the dreaded bird flu and other viruses.10

As with cancer, extremely high doses are needed though — upwards of 200,000 to 300,000 milligrams (mg) of vitamin C, given intravenously. The reason for this is because the avian flu appears to “consume vitamin C very rapidly, similar to an acute viral hemorrhagic fever, somewhat like an Ebola infection.”

A number of other studies and clinical experiences also attest to vitamin C as a potent treatment strategy against all sorts of infectious diseases, including influenza,11 encephalitis and measles.12

Vitamin C for Sepsis

Vitamin C in combination with thiamine (B1) and hydrocortisone has also been shown to be dramatically helpful in the treatment of severe sepsis and septic shock. Sepsis is a life-threatening condition triggered by a systemic infection, caused by bacteria, viruses or parasites that ultimately affects the function of vital organs. Hospital-acquired infections that progress to sepsis is a significant cause of death.

As many as half of all in-hospital deaths are related to sepsis,13 and recent research published in the Canadian Medical Association Journal proposes sepsis should be recognized as a distinct cause of death in hospitals around the world.14 The cost of treating sepsis is high, topping $24 billion in 2014, with nearly 25 percent of all hospital charges attributed to the treatment of sepsis. As reported by Dr. Malcolm Kendrick, the study in question:15

“… demonstrates that if you give vitamin C (along with hydrocortisone and thiamine) for just over two days in patients admitted with sepsis (blood poisoning) the mortality rate falls from 40 percent to 8.5 percent. The mortality rate in low income countries is normally around 60 percent. Now, this was a small study, but it seems robust. It represents an almost five-fold reduction in mortality … ”

Vitamin C Is Also Good for Your Heart, Blood Vessels, Lungs and Eyes

Other studies focused on vitamin C shows it helps:

  • Decrease risk of post-operative atrial fibrillation after heart surgery, thereby reducing the risk of stroke and heart failure. It also reduced the length of hospitalization after heart surgery. Oral administration reduced the length of hospital stay by 7 percent (less than half a day), whereas IV shortened it by 16 percent (1.5 days)16,17
  • Reduce high blood pressure — likely by protecting your body’s supply of nitric oxide (NO), a molecule that relaxes blood vessels. In one study,18 both the systolic and diastolic (top and bottom) readings were inversely associated with ascorbic acid levels. Specifically, women with the highest levels of ascorbic acid had about 4.6 mm Hg lower systolic and just over 6 mm Hg lower diastolic blood pressure compared to those with the lowest ascorbic acid levels
  • Reduce your risk of chronic obstructive pulmonary disease (COPD), especially among smokers. In one study, heavy smokers with the highest vitamin C intake had a 77 percent lower risk of COPD than those with the lowest intake.19 The mechanism for this effect is thought to be related to vitamin C’s ability to improve levels of vascular endothelial growth factor, and boost proliferation of alveolar cells in your lungs
  • Prevent heart attacks, primarily by reducing inflammation20
  • Protect your vision by improving the function of your retinal cells, and reduce your risk for cataracts by fighting oxidative stress

Important Contraindication for IV Vitamin C Treatment

While the evidence strongly supports the use of IV vitamin C in high doses for infections, inflammation and even cancer, it’s important to get your glucose-6-phosphate dehydrogenase (G6PD) checked beforehand. G6PD is an enzyme your red blood cells need to maintain membrane integrity. High-dose IV vitamin C is actually a strong PRO-oxidant, and giving a pro-oxidant to a G6PD-deficient individual can cause hemolysis (rupturing) of their red blood cells.

So, administering IV vitamin C is not for the novice! I strongly recommend getting it done by an experienced practitioner who uses the Riordan protocol or some other protocol that ensures its done in a safe manner. Fortunately, G6PC deficiency is relatively uncommon.

People of Mediterranean- and African decent are at greater risk, but it’s rare even in those groups. Still, while it’s not a great concern that will prevent its use in most people, should you happen to be that rare person with a G6PC deficiency, the ramifications of barreling ahead with high dose IV vitamin C could be disastrous.

General Vitamin C Dosage Suggestions

Dr. Ronald Hunninghake — chief medical officer at the Riordan Clinic who has supervised 60,000 IV administrations of vitamin C — discusses the use of vitamin C for health and cancer protocols in the featured video. For cancer, research by the Riordan Clinic suggests you need a vitamin C blood level of around 300 to 400 mg/dl to achieve selective cytotoxicity against cancer cells.

To reach that post-IV saturation level, you’d need to administer somewhere between 25 to 50 grams of vitamin C intravenously. That’s up to 300 times the normal amount of vitamin C you’d get from eating a healthy diet. It’s important to understand that these extremely high levels are really only indicated for the treatment of cancers and infectious diseases, not for everyday, general health.

This is because vitamin C starts to have a pro-oxidant effect at these extreme levels — this is in fact what causes the hydrogen peroxide to be created in the first place. In other words, the hydrogen peroxide is a pro-oxidant effect of the vitamin C, so it needs to be used judiciously. You can learn more about using vitamin C as an adjunct to your cancer protocol on the Riordan Clinic’s website.21

For everyday health, I believe your best bet is to eat a varied whole food diet, rich in vitamin C and other antioxidants, to avoid causing a nutritional imbalance.

For example, taking large doses of vitamin C (ascorbic acid) on a regular basis lowers your copper level, so if you are already deficient in copper and take high doses of vitamin C, you can compromise your immune system. So, while temporarily taking mega-doses of vitamin C supplements to combat a case of the cold or flu is unlikely to cause a problem, for long-term, daily use, you’re probably going to be better off simply squeezing some lemon juice into a glass of water and/or eating a vitamin C-rich diet.

Also remember that vitamin C is a water-soluble vitamin, so when you do take a supplement, it’s best to divide your daily dose and take it three times a day. Also, if you’re sensitive to vitamin C, you may experience diarrhea. This is an indication that you need to lower your dosage.

Lastly, evidence suggests liposomal vitamin C provides better absorption, so it’s my personal favorite. I always bring some liposomal vitamin C with me when I travel in case I or someone I travel with gets sick, and then I use two to four capsules every hour until better.

Watch the video discussion. URL:https://youtu.be/vX1jtV9wU-g

The Clinical Impact of Vitamin C: My Personal Experiences as a Physician


The Clinical Impact of Vitamin C: My Personal Experiences as a Physician

Is the healing power of Vitamin C too good to be true? Can this inexpensive and convenient vitamin improve and heal the toughest of ailments? 

by Thomas E. Levy, MD, JD

My ongoing relationship with vitamin C now spans a full 20 years, when I first met Dr. Hal Huggins, a pioneering dentist who opened my eyes to a wide array of clinical approaches to different diseases with hitherto unheard-of clinical results at his clinic in Colorado Springs. I can honestly say that my first visit to his clinic began the most meaningful part of my medical education. Nothing has been the same since. My office where I practiced adult cardiology ended up being shuttered shortly after that first visit. And I have never looked back.

While there are many things I learned from Dr. Huggins, and there were many areas I then ended up exploring because of what he taught me, the single most important thing I learned from him was the incredible ability of vitamin C to improve or heal so many conditions. Without exception, seriously ill patients, often with such diseases as Parkinson’s, ALS, Alzheimer’s, MS, and atherosclerosis, almost always had extensive dental toxicity in the form of root canal-treated teeth, infected dental implants, mercury amalgams, extensive cavitational osteonecrosis, and/or advanced periodontal disease. Each of these individuals had anywhere from three to five sessions of extensive dental work, typically involving a great deal of dental surgery along with the inevitable exposure to the toxins associated with anaerobic dental infections and the inescapable assimilation of some mercury vapor if amalgams were being removed. However, all of these patients received 50-gram (50,000 mg) infusions of vitamin C administered continuously before, during, and following the dental sessions. In patients with diseases that I had been led to believe could not really be improved upon, dramatic clinical improvement was routinely apparent immediately following the dental sessions.

While I knew the removal of dental toxicity was very important in their clinical improvements, watching these patients perk up after their first vitamin C infusion was extraordinary. Most healthy people I knew just wanted to go to bed after hours of extensive dental work. On at least one memorable occasion, after the first vitamin C infusion was complete, one especially sickly patient immediately began talking with her caregiver about what restaurant they could go to that evening to enjoy a meal. This patient had several teeth extracted, but was still looking forward to attacking a steak with the remaining teeth in her mouth. On a few priceless occasions, I even saw some wheelchair-bound patients take a few steps, with assistance, before they finished their two-week treatment period at the clinic.

Seeing was believing, and I realized the entire way that I approached patient care simply had to change. I needed to learn a lot more about the intravenous delivery of this molecule known as ascorbic acid, or ascorbate. I resolved to research this vitamin as completely as possible, learn the nuances of that research as best I could, and then proceed to spread the word on the application of this incredibly potent, inexpensive, and non-toxic substance.

Research

Many of the “leads” that I followed in accumulating the many thousands of abstracts and articles came from the 1972 ground-breaking book by Irwin Stone entitled, The Healing Factor: “Vitamin C” Against Disease. Stone obtained forewords for his book by the renowned Nobel Prize winners, Albert Szent-Gyorgyi, who had discovered vitamin C in 1932, and Linus Pauling, who pretty much put vitamin C into the public eye as nobody else has been able to do.

In order not to miss any significant information published in the medical literature about vitamin C since the publication of Stone’s book, I entered the term “ascorbic acid” into the search engine of PubMed, and list of about 24,000 articles appeared. I gave all of these articles careful consideration in documenting the many clinical effects and laboratory effects of vitamin C. What began to emerge as I proceeded to review these thousands of articles was that vitamin C is more important than any other treatment for infection or exposure to toxin. Probably most impressive was the fact that vitamin C in test tube experiments had always neutralized any toxin to which it was exposed, regardless of the chemical structure of the toxin.

The validation and enormous importance of much of this test tube research came from the work of Frederick Klenner, MD in North Carolina. His clinical experience demonstrated how vitamin C was just as effective in the body as in the test tube in neutralizing or negating the toxic impact of whatever toxin the patient was exposed to. Snake venom, heavy metals, pesticides, cyanide, alcohol, carbon monoxide were all neutralized. The results that Dr. Klenner reported with infections were also astounding, as vitamin C, properly administered, proved to be the ultimate virucidal agent, curing all acute viral infections. These viral infections remain incurable by the standard approaches of modern medicine today. Furthermore, Klenner showed that vitamin C was also very effective in the treatment of many non-viral infections, improving the efficacy of treatment by antibiotics and other medications administered today. While I have seen but a fraction of the types of conditions that Dr. Klenner described, I fully believe the accuracy of everything Dr. Klenner published. I have applied vitamin C treatment to many patients with conditions similar to those treated by Dr. Klenner, along with several other conditions that Dr. Klenner did not have the opportunity to treat. With the perspective of this clinical experience, I have little reason to doubt any of the fabulous outcomes that he reported.

What I Have Witnessed

I recall here some of the most dramatic anecdotes about the healing power of vitamin C in the hope of conveying to the reader what an extraordinary addition it can be to the clinical options of any medical doctor. Shortly after the vitamin C book was completed and published, I began a limited clinical practice with a few colleagues. The circumstances were pretty much ideal for me, as I was able to give or prescribeintravenous vitamin C as needed.

Severe Influenza

In 2003 Denver was in the middle of a flu epidemic that infected over 6,000 individuals and ended up killing more than ten children and infants. In this setting, a slender but healthy 26-year-old woman developed a persistent fatigue that continued to progress. After a month of this ongoing fatigue she fell severely ill very quickly, with the classical flu-like symptoms of fever, chills, muscle aches and pains, headaches, and nausea. She tried in vain to deal with her symptoms and still go to school. However, after about a week of these symptoms and trying to maintain a normal level of activity, she only had the energy to stay in bed.

She remained in bed for the next ten weeks. Even her short trips to the bathroom depleted what little energy she had, as the out-of-bed excursions would cause her to feel feverish and would worsen her headaches. When I first saw her, she had lost 20% of her body weight, going from 100 pounds down to about 80 pounds. In response to a plea from her caregiver, I made a house call to her with my office manager/assistant, and we administered her first vitamin C IV there. I found her primarily just emaciated and appearing very malnourished. There was no evidence of liver enlargement or enlarged lymph nodes. Her bloodwork suggested a past Epstein-Barr virus infection, and it was reasoned that this chronic viral infection had just made her all the more susceptible to the epidemic of flu that was working its way through Denver and the rest of Colorado.

Her first IV consisted primarily of 50 grams of vitamin C as sodium ascorbate in 1,000 cc of lactated Ringer’s solution infused slowly over a period of about three hours. Six grams of glutathione was added toward the end of the infusion. The next five infusions contained 100 grams of sodium ascorbate, completed by the six grams of glutathione.

The morning after the first IV she was free of headaches for the first time in three months, and she felt much stronger. However, by the second infusion, she was able to walk a bit around the house. By the morning after the third infusion, she was able to walk outside and enjoy a little sunshine. She was able to walk into the clinic for her fourth infusion and subsequent treatments. She felt completely normal the day after the fourth infusion, but two more infusions over two more days were administered to prevent the possibility of relapse. An oral regimen of supplementation was started, and she was discharged from regular care.

Of particular importance in understanding the amount of vitamin C needed to effectively cure this patient’s chronic/acute viral syndrome is to note the patient’s weight of 80 pounds when first seen. 100 grams of vitamin C in a 80-pound patient is equivalent to 250 grams in a 200-pound patient. Further, the efficacy of the vitamin C was enhanced by the glutathione administration. Our conclusion from many similar cases was that any viral syndrome not resolving with vitamin C was almost always due to inadequate total dose, along with the virus not being readily accessible by the molecules of vitamin C, as in chronic hepatitis. A terminal (not early stage) case of a dangerous virus such as Ebola in a nutrient-depleted body might require even higher doses of vitamin C for clinical resolution, depending upon body size.

H1N1 Influenza

A New Zealand farmer contracted H1N1 influenza in 2009. Well-documented on New Zealand’s version of 60 Minutes, this individual had progressed to the point of being on life support, and the doctors had nothing further to offer.

https://www.youtube.com/watch?v=VrhkoFcOMII or
https://www.youtube.com/watch?v=vTXSTGGRvKY

A family member contacted me to ask what to do, and I advised intravenous vitamin C, 50 grams or more daily, immediately. However, I did not think there was any chance that the hospital or doctors would allow such treatment.

After an enormous struggle, the family finally got the doctor in charge to give vitamin C before “pulling the plug.” 25 grams of vitamin C was given intravenously the first day, 50 grams the second day, 75 grams the third day, and then 100 grams daily for 4 to 5 more days. At that point a new doctor in charge of the case discontinued the vitamin C completely, for unclear reasons, even though the patient was clearly responding, waking up, and dramatically clearing up the previous “white-out” state seen in chest X-rays of his congested lungs. A full week later, intravenous vitamin C was restarted at a mere one gram twice daily. But for the docs who thought the vitamin C was a foolish intervention, the proof of its efficacy was already at hand.

Pulmonary Embolism

While visiting Colombia, South America, I had the opportunity to see a 30-year-old woman who was bedridden and appearing to be in imminent danger of dying. She had been diagnosed with pulmonary embolism, and both of her legs were tender and swollen, appearing ready to set loose further emboli that would seal her fate. She was already on Coumadin anticoagulation, and her blood tests indicated the thinning of her blood was optimal.

Since I had brought some supplies with me on this trip in order to give a few selected friends (as well as myself) some intravenous vitamin C, I decided to try to help this individual out as best I could. While I was concerned about the vitamin C neutralizing the anticoagulant effects of the Coumadin, I was hoping to relieve her suffering a bit. I proceeded to give her 50 grams of vitamin C over about three hours. She tolerated the infusion well.

The following afternoon I returned to give her another vitamin C infusion. Her improvement was nearly miraculous. She was sitting up in bed and combing her hair, as she had just gotten out of bed and taken a shower on her own.

On the fourth day, following the third infusion, she was smiling and very pleased to report how good her legs were feeling. I was very pleased, but I was also concerned over the possibility of relapse, as I could not continue the IV infusions. She did continue to improve, however, as I left her with several months worth of vitamin C powder, taken at 2,000 mg daily.

West Nile Virus

I have treated two cases of West Nile virus, and both responded very dramatically. A Colorado man in his 60s had already been sick for a month or two when he went to his local hospital and ended up testing positive for West Nile virus. His symptoms included persistent headaches, a bit of disorientation, and a low-grade fever. Upon arrival at my clinic, he was given 75 grams of vitamin C intravenously followed by 6 grams of glutathione intravenously. He was also given a hyperbaric oxygen treatment. By 36 hours post-treatment, he felt completely normal and remained so.

Another man in his 50s contracted the West Nile virus and presented with a history of chronic virus-associated symptoms over the preceding six months. He received three infusions of vitamin C on consecutive days and reported having no further symptoms after the completion of the third infusion. There was no clinical relapse, and the cure was complete. He commented that the whole experience seemed “like a miracle.”

Infectious Mononucleosis

Two college students presented with chronic infectious mononucleosis. Both had been sick for months, primarily with severe fatigue, and they had already dropped out of their classes, not having the energy to continue. Both received several 50-gram infusions of vitamin C and had prompt, complete resolution of their chronic infections and persistent symptoms.

Acute Lyme Disease

A young woman in Pennsylvania was bitten by a pathogen-carrying tick, developed the classical Lyme-associated rash, and proceeded to get very ill over the next seven to ten days. She received several infusions of vitamin C at her house. The first infusion was 100 grams, and her caregiver reported that she seemed much improved upon the completion of that infusion. Five more infusions of 50 grams each were given over the next two days. By the time that 72 hours had passed, she was completely well, never having a clinical relapse or any chronic Lyme symptoms.

Chronic Lyme Disease

A woman with a 12-year history of chronic Lyme disease, documented by blood testing, desired having regular and prolonged high-dose intravenous vitamin C therapy for her condition. Under the aegis of a prescribing physician who had attended one of my presentations of vitamin C, a nurse practitioner was able to give the patient what she wished.

This individual had already been taking liposome-encapsulated vitamin C and glutathione orally without a significant improvement in her condition. On four consecutive days, she received infusions of 25, 50, 75, and then 100 grams of vitamin C. Then, for 19 more days, she received 5 or 6 infusions weekly of 100 grams of vitamin C in each infusion. Until day 23, she felt no improvement. However, she was determined to continue in spite of the lack of improvement and the increasing expense of the whole process. On day 23, the nurse practitioner reported that she looked like a new person, and that it was like a “switch was flipped” and she was well. At her request, the patient received another week of 100 gram daily infusions to be sure her condition was truly resolved, a very good idea on her part. About a month later, her Lyme blood testing was completely negative.

A physician reported to me similar experiences with a series of Lyme patients, who showed no positive clinical response after an extended number of vitamin C infusions, then had a dramatic, abrupt clinical resolution of their condition, very much as described above.

Final Notes

Vitamin C is truly Nature’s gift to health and healing. Virtually all medical conditions are associated with increased oxidative stress, and the relief, or at least partial relief, of this oxidative stress with the vigorous administration of vitamin C and other quality antioxidants, will always help. The oxidative stress caused by disease and environmental toxins can deplete the body’s level of vitamin C and other antioxidants. In serious illness, the body’s reserve of vitamin C goes to zero because the rate at which the body regenerates it is far lower than the rate of depletion. This can require huge doses to bring it back to normal. Even if you are taking antibiotics or other prescription medicines, bringing your levels of vitamin C in your body back to normal, or temporarily supranormal, will virtually always result in profound benefits.

The treatment is effective and, compared to the expense of conventional treatment, it is inexpensive. Few medicines and therapeutic interventions are more affordable than, and as non-toxic as, vitamin C. Even though something as extraordinarily beneficial as vitamin C might seem too good to be true, that’s definitely not the case.

Vitamin C proven to cure over 30 major diseases


Over 75 years of medical research and clinical practice reveals, overwhelmingly, that vitamin C has the power to ignite the ‘self-healing response’. I know what you’re thinking – if vitamin C is so good for us – why haven’t you been told about this curative nutrient? Well, the answer will soon become painfully obvious.

Vitamin C

Medical students receive little nutritional training – only 2 hours in 4 years! Vitamin C therapy for a host of chronic diseases has been systematically ignored by conventional medicine for decades. On the next NaturalNews Talk Hour, meet Dr. Andrew Saul and learn about the true power of high-dose vitamin C therapy.

Dr. Fredrick R. Klenner discovers the real power of vitamin C and how to cure disease

Believe it or not, in the 1940’s, Dr. Klenner used vitamin C to cure 60 out of 60 cases of polio and that was back in the days when the polio vaccine didn’t even exist. Dr. Klenner even presented his findings – at a large medical conference about his success with high dose vitamin C therapy and it was largely ignored.

Instead, big pharma has a stranglehold ‘death grip’ over the I.Q. of most doctors – brainwashing them into believing that toxic antibiotics that destroy intestinal flora (and the immune system) is a ‘wiser’ choice.

Dr. Klenner was one of the first physicians to cure disease with vitamin C. In fact, he consistently eliminated chicken pox, measles, mumps, tetanus and polio with huge doses of IV vitamin C. And, keep in mind, Dr. Klenner did this when vaccines didn’t even exist.

These are the medical facts. Dr. Klenner cured pneumonia, encephalitis, herpes zoster (shingles), herpes simplex, mononucleosis, pancreatitis, hepatitis, rocky mountain spotted fever, bladder infections, alcoholism, arthritis, some cancers, leukemia, atherosclerosis, ruptured intervertebral disc, high cholesterol, corneal ulcers, diabetes, glaucoma, radiation burns – the list goes on and on.

He published dozens of papers – just ‘google’ Dr. Klenner and you’ll be amazed at what you find.

Want to learn more about vitamin C therapy? Jonathan Landsman and Andrew Saul, Ph.D. invite you to join us on the next NaturalNews Talk Hour – Sunday, Oct. 20th for an informative program on how to virtually eliminate disease with high dose vitamin C therapy.

Visit: http://www.naturalhealth365.com and enter your email address for show details + FREE gifts!

What do experts have to say about the healing power of vitamin C?

“Some physicians would stand by and see their patient die rather than use ascorbic acid (Vitamin C) because in their finite minds it exists only as a vitamin.” – Dr. Fredrick Klenner

“Vitamin C is the world’s best natural antibiotic, antiviral, antitoxin and antihistamine. Let the greats be given their due. The importance of vitamin C cannot be overemphasized.” – Andrew Saul, Ph.D.

“Man’s body was designed to function best with high blood and cellular levels of vitamin C – synthesized as needed by the liver.” – Thomas E. Levy, MD, JD, board-certified cardiologist

“I always look upon high dose vitamin C as nature’s way of dealing with crisis in terms of your health. This notion however does not exist in the conventional thinking of the medical mind.” – Ronald Hunninghake, M.D. – personally supervised over 60,000 intravenous (IV) vitamin C sessions

“More and more physicians are getting convinced about the value of large doses of Vitamin C.” – Linus Pauling, 2-time Nobel Prize winner

If you’re still not convinced at the safety and effectiveness of vitamin C therapy – I encourage you to look up the work of the Riordan Clinic plus many other experts in vitamin C like, Drs. Irwin Stone, Abram Hoffer, Robert Cathcart plus many others – listed above. Or, on the next NaturalNews Talk Hour, join us for an interesting show about how vitamin C can cure disease.

This week’s guest: Andrew Saul, Ph.D., natural healthcare pioneer and nutritional therapy expert

Find out what conventional medicine has never been taught about vitamin C and healing – Sun. Oct. 20

Andrew W. Saul, Ph.D. taught nutrition, addiction recovery, health science, and cell biology for a total of nine years for the State University of New York, and clinical nutrition for New York Chiropractic College. Since 2005, Dr. Saul has served as Editor-In-Chief of the Orthomolecular Medicine News Service for over 140 issues.

In 2006, Psychology Today named Dr. Saul as one of seven natural health pioneers. He has won the Citizens for Health Outstanding Health Freedom Activist Award, is an Honorary Director of the Gerson Institute, and is featured in the documentary Dying to Have Known: The Evidence Behind Natural Healing and the very popular FoodMatters movie. The author or co-author of many books – his expertise on the topic of nutritional therapies for disease is second to none.

Learn more: http://www.naturalnews.com/042541_vitamin_C_natural_cures_Andrew_W_Saul.html#ixzz459qhx8Hm

Vitamin C helps improve post-exercise breathing difficulties


Vitamin C may help ease exercise-induced breathing problems, according to a study conducted by researchers from the University of Helsinki, Finland, and published in the journal Allergy, Asthma & Clinical Immunology.

Some people, including many with asthma, suffer from bronchoconstriction or other forms of respiratory distress after exercising. Prior studies have suggested that this bronchoconstriction is mediated in part by histamines, prostaglandins and cysteinyl leukotrienes, all of which are metabolized through processes that rely on vitamin C. In addition, vitamin C is a potent antioxidant, and might therefore disrupt the oxidative pathways that have also been linked to exercise-induced respiratory distress.

Regular metabolic processes cause the release of oxidative compounds, also known as free radicals. These chemicals can then cause damage to cells and DNA. Free radical production accelerates during exercise.

Vitamin C improves breathing 50 percent or more

The researchers carried out an analysis of several prior studies. In three of those studies, vitamin C was found to reduce the post-exercise decline of FEV1 by 50 percent. FEV1, or forced expiratory volume, is the amount of air that you can force out of your lungs in one second.

Analyzing another five studies showed that respiratory symptoms decreased by 50 percent when people under short-term, heavy physical stress were given vitamin C. Yet another found that male adolescent competitive swimmers given vitamin C experienced a 50 percent decrease in the duration of exercise-induced respiratory symptoms.

Because FEV1 measures only the obstruction of large airways, the researchers also re-analyzed a prior study that looked at the effect of vitamin C on exercise-induced decline in FEF25-75 and FEF60, which measure small airway obstruction. Typically, FEF25-75 and FEF60 decrease twice as much as FEV1 in those with exercise-induced bronchoconstriction.

The study consisted of 12 people of average age 26 who suffered from asthma and from exercise-induced bronchoconstriction. Participants were given vitamin C or a placebo on separate days, and their FEV1 and FEF60 levels were measured both before and after exercise. The data from the study had not previously been thoroughly analyzed.

Among participants who experienced a significant drop in FEF60 following exercise (5 of the 12), vitamin C increased post-exercise FEF60 levels by 50 to 150 percent.

“[G]iven the safety and low cost of vitamin C,” said researcher Harri Hemila, “and the consistency of positive findings in the nine randomized trials on vitamin C against exercise-induced bronchoconstriction and respiratory symptoms, it seems reasonable for physically active people to test whether vitamin C is beneficial on an individual basis, if they have documented exercise-induced bronchoconstriction or suffer from respiratory symptoms such as cough or sore throat after taking vigorous exercise.”

Also protects in lung disease

Prior research has also indicated that vitamin C may improve muscle function in people with chronic obstructive pulmonary disease (COPD). In COPD, lung function progressively worsens and the function of skeletal muscles degrades, making ordinary activities difficult or impossible.

The mechanisms of COPD-induced loss of fitness are unclear. Some suggested factors include inadequate oxygen to the muscles, loss of fitness due to inactivity, damage to cells’ metabolic processes and oxidative stress.

A study conducted by researchers from the George E. Whalen VA Medical Center and the University of Utah and published in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology found that COPD patients given intravenous vitamin C experienced less muscle fatigue following knee flex exercises. In addition, patients’ breathing slowed and improved, the antioxidant activity in their blood increased, and their resting blood flow and blood pressure decreased.

The findings strengthen the evidence that oxidative stress plays a key role in COPD symptoms, including loss of muscle function.

“Targeting oxidative stress with some form of antioxidant therapy in a clinical setting may represent an important therapeutic avenue for patients with COPD,” the researchers wrote.

Learn more: http://www.naturalnews.com/052734_vitamin_C_breathing_problems_exercise.html#ixzz3yXvl485l