Fish oil increased adiponectin in humans

Fish oil consumption may improve insulin sensitivity and adipocyte function, according to data from a meta-analysis of randomized controlled trials

Using data from 14 trials, Jason Wu, PhD,and colleagues at the Harvard School of Public Health, along with the University of Western Australia, Brigham and Women’s Hospital and Harvard Medical School, aimed to determine the effects of consuming long-chain polyunsaturated omega-3 fatty acids (n-3 PUFA) on circulating adiponectin in humans.

Participants in the 14 trials received fish oil at a median dose of 1.3 g/day for a median of 8 weeks (n=682) or placebo (olive and sunflower oil were most commonly used; n=641).

Fish oil was associated with a 0.37-mcg/mL (95% CI, 0.07-0.67) increase in adiponectin. According to the study results, statistical heterogeneity was evident but unexplained by n-3 PUFA dose or duration, study quality score, study location or baseline BMI (P>.05 each).

Two trial arms in one study examined the effect of fish meal feeding on adiponectin, but it was not statistically significant (–0.01 mcg/mL; P=.99).

“These findings support potential beneficial effects of fish oil supplementation on pathways related to adipocyte health and adiponectin metabolism,” Wu and colleagues wrote.

Source: Endocrine today




Structures may cause jellyfish blooms.

Human-made structures such as harbours, tourist facilities, oil rigs and aquaculture farms provide ideal sanctuaries for jellyfish polyps to flourish and may explain an apparent increase in jellyfish blooms in many coastal waters around the world.

That’s the conclusion of a new study published by a group of international researchers, including lead author Winthrop Professor Carlos Duarte, Director of the Oceans Institute at The University of Western Australia.

Their paper “Is global ocean sprawl a cause of jellyfish blooms?” appears in the journal Frontiers in Ecology and the Environment.

Professor Duarte said most theories that seek to explain increased jellyfish blooms focus on jellyfish at their more mature swimming stage and factors such as a lack of predators or competitors due to overfishing.

But the new study examined the tiny polyp phase of jellyfish and found they congregate in millions on the underside of human-made structures.

“We call this new proposition the ‘Trojan Horse‘ hypothesis,” Professor Duarte said.

“The proliferation of artificial structures such as harbours, shipping facilities and aquaculture structures provides a habitat for jellyfish polyps and may be an important driver in explaining the global increase in jellyfish blooms.”

Professor Duarte said jellyfish larvae typically settle on a hard surface and grow into polyps as part of a colony.  The polyps are generally inconspicuous because they are very small – usually only a millimetre or so in length.

The study examined polyps growing on a variety of man-made structures around the world – including in Japan, Britain, Spain and Slovenia – and looked under docks, piers, pontoons and artificial reefs, and on the underside of oysters attached to piers.

“Jellyfish polyps existed on the underside of such artificial structures at densities of more than 10,000 individuals per square metre, and sometimes up to 100,000 per square metre,” Professor Duarte said.

Research was also conducted in Chesapeake Bay in the US and in a laboratory with a Mediterranean jellyfish species to examine how larvae settled on oyster shells, flagstones and 16 other surfaces, including bricks, ropes, cans, wood, concrete and plastic.

Source: Science Alert