Understanding the many benefits of cannabis in cancer treatment

Image: Understanding the many benefits of cannabis in cancer treatment

A cancer diagnosis is both devastating and terrifying. Patients are almost always directed towards conventional cancer treatments like surgery, chemotherapy and radiation, and are made to feel that any other, more “natural” treatments are not only ineffective but dangerous.

The truth is, however, that mainstream cancer treatments wreak havoc on the body, leaving it defenseless against disease and breaking it down at the exact time when it needs to be as strong as possible. With its less than impressive success rate of between 2 and 4 percent, along with its devastating effects on the body, it is unsurprising that three out of every four doctors say they would refuse chemotherapy as a treatment option if they themselves became ill.

While doctors like to promote the idea that there are no treatments scientifically proven to work besides the usual surgery/chemotherapy/radiation regimen, the truth is there is a strong body of evidence that many natural, non-invasive treatments are effective in the fight against cancer. One of the most well-researched and solidly proven of all these natural medicines is cannabis.

The miraculous power of cannabinoids

As noted by Dr. Mark Sircus, writing for Green Med Info, there is no confusion about whether marijuana is an effective cancer treatment. Cannabis has been scientifically proven to kill cancer cells without the devastating and body weakening effects of conventional cancer treatments.

The marijuana plant contains about 113 powerful chemical compounds known as cannabinoids. The most well-known of these compounds are tetrahydrocannabinol (THC) – the chemical that induces marijuana’s “high” – and cannabidiol – a non-psychoactive compound which has been extensively studied as a cure for many diseases.

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These and other cannabinoids are what make marijuana such a potent anti-cancer treatment, as reported by Green Med Info:

Cannabinoids are found to exert their anti-cancer effects in a number of ways and in a variety of tissues.

  • Triggering cell death, through a mechanism called apoptosis
  • Stopping cells from dividing
  • Preventing new blood vessels from growing into tumors
  • Reducing the chances of cancer cells spreading through the body, by stopping cells from moving or invading neighboring tissue
  • Speeding up the cell’s internal ‘waste disposal machine’ – a process known as autophagy – which can lead to cell death

All these effects are thought to be caused by cannabinoids locking onto the CB1 and CB2 cannabinoid receptors. Almost daily we are seeing new or confirming evidence that Cannibinoids can be used to great benefit in cancer treatment of many types.


What the science says

Scientific studies published in a host of peer-reviewed journals have confirmed marijuana’s powerful ability to fight breast, lung, ovarian, pancreatic, prostate and other cancers.

A meta-analysis of over 100 published studies, performed by researchers from Germany’s Rostock University Medical Centre, concluded that cannabis both boosts immunity and fights cancer.

The Daily Mail reported:

Scientists are calling for more studies to be done on humans after studying the cancer-fighting effects of chemicals in the drug.

Studies suggest chemicals called phytocannabinoids could stop cancer cells multiplying and spreading, block the blood supply to tumors, and reduce cancer’s ability to survive chemotherapy. …

The new research review admits cannabis has ‘anti-cancer effects’ and says more research needs to be done in real patients to confirm the findings.

It takes real courage to receive a cancer diagnosis and decide not to follow mainstream advice but seek alternative treatments. But even for those who choose to receive conventional cancer treatments like radiation and chemotherapy, cannabis can still be an important part of their overall wellness plan. As Dr. Sircus admonishes, “Every cancer patient and every oncologist should put medical marijuana on their treatment maps.”

Benefits of Medical Cannabis for Resistant Epilepsy Time-Limited?

Patients with treatment-resistant epilepsy can develop a tolerance to cannabis-based therapy, a finding that may have implications for long-term management, new research suggests.

Dr Shimrit Uliel-Sibony


“Physicians should be aware that tolerance may occur,” study investigator Shimrit Uliel-Sibony, MD, pediatric epileptologist, Dana-Dwek Children’s Hospital, Tel Aviv University, Israel, told Medscape Medical News.

“There’s this notion that cannabis is a great medicine, that it’s much better in terms of response rates than other interventions for patients with treatment-resistant epilepsy, but that may only be at the beginning,” she added.

Long-term exposure may produce a different picture. With time, efficacy may decrease, resulting in a need to increase the dose. This suggests the development of tolerance.

“We know marijuana may have cognitive consequences with long-term, chronic recreational use. I think we need to be a little more cautious on our expectations of this therapy,” said Uliel-Sibony.

The study was presented here at the American Epilepsy Society (AES) 72nd Annual Meeting 2018.

Few Long-term Data

In the recent past, many studies have suggested that medical cannabis is superior to traditional antiepileptic drugs (AEDs). Studies have reported dramatic improvement in seizure control, as well as a favorable safety profile.

However, said Uliel-Sibony, there is a need for data on long-term safety and efficacy. The long duration of treatment, the investigators note, “raises the possibility of withdrawal and tolerance.” Some animal studies suggest that prolonged exposure to tetrahydrocannabinol (THC), the psychoactive ingredient in cannabis, but not cannabidiol (CBD) leads to tolerance.

To assess the long-term efficacy of cannabinoids as well as the development of tolerance in the treatment of refractory epilepsy, the investigators conducted an observational, longitudinal study of pediatric and adult patients.

The analysis included 92 patients (59 males) ranging in age from 1 year to 37 years (mean age, 11.8 years). All had treatment-resistant epilepsy; two had Dravet syndrome; and three had Lennox-Gastaut syndrome (LGS). The remainder had other types of seizures and epilepsy syndromes.

All patients had experienced treatment failure with numerous drug therapies, and for some, use of the ketogenic diet or vagal nerve stimulation therapy was also ineffective. None had been previously treated with medical cannabis.

Participants were initially given a cannabis oil extract in which the ratio of CBD to THC was 20:1. That amount of THC has negligible psychoactive activity, noted Uliel-Sibony.

The patients had been receiving stable doses of AEDs for at least 4 weeks before study enrollment. All participants had at least 3 months of follow-up (mean follow-up, 20 months).

No “Honeymoon” Tolerance

Tolerance was defined as a 30% or greater reduction in response rate that continued for more than 3 months.

Patients in whom efficacy decreased during the first 3 months of treatments were not included. The intention was to exclude patients who showed short-lasting improvement that was possibly the result of the “honeymoon” effect.

The investigators found that about 29% of the study population experienced a reduction in seizures by 50% to 75%.

Of 84 patients included in the tolerance analysis, 25% developed tolerance, which was reported with an average dosage of 12.6 mg/kg/day.

This dosage is lower than in some studies that used more purified cannabis. There was some suggestion that combining CBD with a very small amount of TCH “enables use of a lower dose of CBD,” a phenomenon referred to as the entourage effect, said Uliel-Sibony.

None of the patients with Dravet syndrome or LGS developed tolerance, she added.

In an attempt to counteract tolerance, the CBD dose was increased. Using this approach, about 20% of the patients were able to achieve the same response rate as before the development of tolerance, but this was not the case for almost half of the cohort.

In some patients, tolerance was reversed by gradually reducing the CBD dose, waiting 2 to 3 weeks, and then restarting the medication at the same dose that achieved response.

The tolerance may be due to “receptor desensitization,” said Uliel-Sibony. “If we take patients off the medicine, the receptors become sensitive again.”

This new study used two similar CBD products that are available in Israel. There was no difference between the two products in terms of tolerance.

It is not clear whether the tolerance seen in the study was due to the presence of THC. The literature on the subject suggests that there is no tolerance to CBD, only to THC, she said.

But it may be a question of exposure. In this study, the mean time for tolerance to occur was 7.3 months.

“Tolerance is something that develops over time,” said Uliel-Sibony.

Having a small amount of THC in the product seems to have some positive side effects, she said. Parents reported that children showed improvements in sleep and appetite and that they were more alert.

Great Expectations

She noted that overall, the side effect profile for the formulation is superior to that reported in other studies that used a more purified formulation of CBD. Of the 87 patients included in the safety analysis, 51% experienced adverse reactions.

Uliel-Sibony hopes to continue to follow the patients in the study for a longer period “to get a better picture” of tolerance, she said.

But she recognizes the challenges of following this patient population. Moreover, even if the number of seizures is reduced by half, for those patients who were having 10 seizures at the start of treatment, the condition is still not well controlled.

She believes expectations are high for cannabis-based therapy. She cited one study that showed that parents who relocated to Colorado just to access one of the early CBD treatments for epilepsy reported better response to the drug.

Families may be misled by some of the hype surrounding medical marijuana, said Uliel-Sibony. “Parents believe they’re giving their child something natural, something that isn’t really a chemical, but CBD is a medicine like any other.”

She noted that her study has limitations, including the fact that it is not randomized controlled trial.

THC Makes Cannabis Ideal for Treating Asthma, Study Shows


For many , the idea of cannabis being used as an asthma treatment can feel a bit backwards. After all, one of the most common ways cannabis is ingested is by smoking, a method that would seem to be detrimental to those with asthma. However, recent studies have found that cannabis in any form (even smoked) can greatly benefit those suffering from the symptoms of asthma.

Can Marijuana Treat Asthma?

First let’s take a closer look at asthma and what it actually means to have it. Asthma is a fairly common lung disease that results in the narrowing of the airway passage. Due to this narrowing, those suffering from asthma frequently experience feeling out of breath, wheezing or uncontrollable coughing.

While treatment can be used to reduce the effects patients with asthma experience, there is currently no cure for the condition. Asthma attacks can come in many forms and can be triggered by a number of factors including allergies or exercise. While asthma doesn’t reduce your life expectancy, being caught in an intense asthma attack without the proper treatment can be fatal.

So how does a substance that can be smoked help treat asthma? The explanation can be found by examining where asthma begins. Asthma is a chronic inflammatory disease, while cannabis is known for its powerful anti-inflammatory effects. This means cannabis works in an opposite effect to other substances like tobacco and can actually help expand the lungs instead of constricting them. 

Editor’s Note: A 2015 animal study in the Journal of Pharmacology and Experimental Therapeutics identified THC specifically as the active compound in cannabis that could benefit people suffering from asthma. They found that THC had anti-inflammatory and bronchodilator effects on airways (very similar to the effect Ventolin has on the lungs during an asthma attack). This is great news! 

So how powerful can a cannabis treatment actually be? For those suffering from an asthma attack the results are practically instantaneous and are similar to the results found with some of the more common name brand inhalers. 

If you or someone you know is suffering from asthma and would like to seek cannabis as a treatment option, be sure to check out your state’s list of qualifying medical conditions for medicinal cannabis to see if you are eligible for such a treatment option.

Other Ways to Treat Asthma Naturally

If you’re looking for more natural forms of asthma treatment, talk to your doctor about the following options:

How Long Does Weed Stay In Your System?

Irecently opened a Snapchat from my best friend informing me that she had been fired from her job because she failed a drug test.

Jasmine does not do drugs — her idea of a wild night includes catching up on “Jane the Virgin” while sipping Moscato. I started to panic, thinking, “My best friend has totally gone off the deep end.” Some form of telepathy must have kicked in, because seconds later, I received a text assuring me everything was okay.

The job loss wasn’t a tragedy: Jasmine was already planning to submit her two weeks notice. We spent the next few minutes laughing about how dumb it was that she lost her job because of a poppy seed (during the harvesting process, poppy seeds absorb opium extract, which can cause your pee to test positive for morphine). After we hung up, I started to wonder: How long does it take before a drug is out of your system?

According to the US Anti-Doping Agency, it can take up to 48 hours for drugs like morphine and codeine to pass through your system. But what about marijuana? It seems like all the cool kids are doobie-ing it up these days.

Green Rush Daily explains that the most common way for an employer to track your marijuana usage is through a urine test. These tests don’t detect THC (the ingredient in weed that makes makes you feel high). Instead, urine tests look for THC-COOH, a derivative chemical your body produces after smoking or ingesting weed. THC-COOH stays in your system longer than THC, which explains why you might fail a drug test, even weeks after a smoke session.

The more you smoke, the longer it takes for marijuana to completely exit your body. Here’s a quick breakdown:

  • First time smokers usually test positive for marijuana for five to eight days after using.
  • If you smoke two to four times in a week, THC-COOH will remain in your urine for approximately 11–18 days.
  • Smokers that get high five to six times a week will test positive for over a month after smoking.
  • If you smoke weed every day, THC-COOH can remain in your urine for up to 77 days.

Some weed enthusiasts claim that drinking water and cranberry juice can help you pass a drug test. Unfortunately, consuming too many fluids can dilute your urine, which may compromise your test results.

Sorry, marijuana lovers; it’s hard to outsmart science. Even the best employees can be brought down by a poorly timed drug test. When it comes to your weed (and poppy seed) use, tread lightly.


Revolutionary Cannabis Patch Successfully Treats Fibromyalgia and Nerve Pain (without getting you high!) 

In November 2016, Cannabis Science announced 2 new pharmaceutical developments in the form of cannabis skin patches for pain. Representatives claim the skin patch will be more effective than cannabis-based topical creams, pills, or injections due to its more accurate dosing (1).

Currently, the skin patches are not yet available and no official date has been given by Cannabis Science for clinical trials. Nevertheless, should research and development progress as expected, the cannabis skin patch could prove to be a much-needed new option for treating complicated chronic pain conditions including fibromyalgia and diabetic neuropathy.

Does Cannabis Work for Treating Pain?

medical marijuana

The most common natural plant cannabinoids (phytocannabinoids) are: THC, cannabidiol (CBD), cannabigerol (CBG), cannabichromene (CBC), and cannabinol (CBN). While the majority of research and public attention has been directed at THC, the new skin patch development uses the CBD, otherwise known as cannabidiol(1).

Research shows that CBD has several beneficial properties, including (5):

  • anti-inflammatory
  • analgesic (pain relief)
  • greater antioxidant activity than vitamins C or E
  • neuroprotective

CBD is a non-euphoriant, and some research actually suggests that this particular cannabinoid reduces the effect of the other euphoriant cannabinoids, lessening their psychoactive effects including panic, anxiety, intoxication, and heart palpitations. In short, taking isolated CBD will not alter your state of mind like smoking or consuming marijuana would.

Cannabis Science CEO, Raymond Dabney states, “As more states nationwide legislate for the legalization of Cannabis and Cannabis derived medications, we here at Cannabis Science are focused on developing pharmaceutical formulations and applications to supply the huge growing demand expected over the coming few years.”

medical uses for cannabis

Thanks to a growing body of research exploring the medical uses of cannabis, and a cultural openness to medical marijuana use, the cannabis skin patch may soon be a real option available to those suffering from painful conditions like diabetic nerve damage and fibromyalgia.

Diabetic Neuropathy and Cannabis

Diabetic neuropathy is a group of nerve disorders associated with diabetes. While nerve damage can start at any point for those with diabetes, people who have had diabetes for 25 years or more or who have difficulty managing their blood sugar or blood pressure levels, have the highest risk (2).

Since nerve damage can occur in every organ system, symptoms can be varied. Some people with nerve damage won’t experience any noticeable symptoms at all. The 4 main types of diabetic nerve damage come with their own unique set of symptoms:

Diabetic Nerve Damage Symptoms

1. Peripheral Neuropathy: The most common type of neuropathy is peripheral neuropathy, which usually manifests in hands and feet as (2):

  • numbness
  • tingling
  • sharp pain
  • sensitivity to touch and temperature

2. Autonomic Neuropathy: This type of nerve damage affects the cardiovascular system, eyes, digestive tract, sex organs, urinary tract, and sweat glands. Symptoms include (2):

  • noticeable changes in digestion and bladder function
  • sexual dysfunction in both men and women
  • inability to manifest usual warning signs of low blood sugar
  • trouble seeing at night
  • profuse sweating

3. Proximal Neuropathy: Proximal neuropathy is localized in the legs. It’s associated with (2):

  • pain in legs, hips, thighs or bottom
  • noticeable weakness in leg muscles

4. Focal Neuropathy: This form of nerve damage can affect any nerve in the body (but most often in the head and arms), causing weakness and pain. Other symptoms include (2):

  • vision problems, aching around eyes
  • facial paralysis
  • acute pain in chest, stomach or abdominals

How Is Diabetic Nerve Damage Treated?

Conventionally, doctors will prescribe patients with diabetic nerve damage painkillers, anticonvulsants or antidepressants such as oxycodone, Ultram, amitriptyline, Cymbalta, or Lyrica. Additionally, they will work with the patient to help keep blood sugar levels balanced.

Should Cannabis Science’s skin patch go through clinical trials and be approved by the FDA, it would provide a more natural and effective way to manage pain from diabetic nerve damage without risk of addiction (a massive problem with opioid prescriptions).

Fibromyalgia and Cannabis

cannabis patch to treat fibromyalgia

Fibromyalgia syndrome is a chronic condition often grouped together with arthritis, although it is not an arthritic condition. Fibromyalgia affects mostly women. A 2008 report estimated that about 5 million adult Americans suffer from fibromyalgia (4). Sufferers of fibromyalgia experience chronic non-localized pain, tenderness, and intense fatigue. Sometimes, fibromyalgia is accompanied by other symptoms including (3):

  • brain fog
  • headaches
  • morning stiffness
  • restless leg syndrome
  • painful menstrual cramps
  • irritable bowel syndrome

How is Fibromyalgia Treated?

Unfortunately, fibromyalgia can be tricky to treat; this is complicated by the fact that many medical providers are not familiar with fibromyalgia or its various treatments. The FDA has currently approved 3 drugs for fibromyalgia treatment: Duloxetine, Milnacipran, and Pregabalin.

The Cannabis Science skin patch might be a promising treatment option for many fibromyalgia patients, especially those for whom the 3 current drugs don’t have an effect. It would also provide a less risky solution than the current drugs, which come with their own long lists of side effects and long-term risks.

Help us spread awareness of this potential new treatment by sharing this article with your friends and family. We will continue to follow the development of the Cannabis Science skin patch and provide updates as new studies and trial information becomes available.


Cannabis Compound Found to Remove Toxic Alzheimer’s Protein From the Brain.

Alzheimer’s is a major problem, and as Americans continue to age, it’s becoming an increasing one. But what if cannabis had the answer?

According to Real Farmacy, cannabis is the answer – as a compound (THC, more specifically) can remove toxic amyloid beta protein clumps, which some believe are responsible for Alzheimer’s disease, from the brain.
Marijuana enthusiasts the world over are already rejoicing, simply because they heard THC. Smoke ’em if you got ’em?
Researchers are suggesting that THC works to fight Alzheimer’s by clearing those protein clumps, thereby decreasing the likelihood of the lesions some researchers believe are responsible for Alzheimer’s.
In 2006, researchers at the Scripps Research Institute found that THC inhibits the formation of amyloid plaques by blocking the enzyme in the brain that produces them. Schubert and his team have found that THC is also able to eliminate a dangerous inflammatory response from the nerve cells, thus ensuring their survival.

So far, Schubert and his team have only tested THC on neurons in a lab. Their next step will be to observe the link between THC and reduced inflammation and plaque build-up in a clinical trial.

THC is a popular word among marijuana enthusiasts because it is responsible for the majority of marijuana’s psychological effects, including the high. THC has natural pain-relieving properties, and is effective in treating symptoms for everything from stroke and chemotherapy to chronic pain, post traumatic stress disorder, and HIV.

When consumed, THC passes from the lungs to the bloodstream, and attaches itself to two different types of receptors, cannabinoid receptor (CB) 1 and 2. These receptors are found on cell surfaces all over the body.

Receptors in the brain are most concentrated in neurons associated with pleasure, memory, thinking, coordination, and time perception. These receptors usually bind with a class of lipid molecules called endocannabinoids that are produced by the body during physical activity to promote cell-to-cell signaling in the brain.

THC can also bind to these lipid molecules in the same way. When THC does this, it begins to mess with the brain’s ability to communicate with itself. This can be both a good and a bad thing.

Research suggests that by binding to these receptors, THC could actually have a positive effect on aging brains because it can help the body clear out toxic accumulations of amyloid beta.

While no one is 100% sure of what causes Alzheimer’s disease, it is thought to be the result of a build-up of two types of lesions: amyloid plaques and neurofibrillary tangles.

Amyloid plaques are dense clusters of beta-amyloid molecules that sit between neurons. Neurofibrillary tangles are caused by defective tau proteins that clump up into a thick, insoluble mass in the neurons.

It is still unclear why these lesions begin appearing in the brain, but studies have linked inflammation in the brain tissue to the build up of plaques and neurofibrillary tangles. According to these studies, something that is capable of easing brain inflammation while simultaneously encouraging the body to clear out these lesions could become the first effective treatment for Alzheimer’s.

Lawsuit Alleges That NFL Teams Distributed Painkillers Recklessly

The National Football League (NFL) has been buffeted by the health controversies for the last few years. In 2014, the horrors of chronic traumatic encephalopathy (CTE) were first brought to the public’s attention in the form of a Boston University study. That athletes who suffered multiple concussions were at increased risk of cognitive impairment was known before this study, but the extent and pervasiveness of the problem was underestimated.

CNN reports that the NFL is now the focus of a lawsuit concerning their “reckless” use of opioid painkillers. These prescription drugs are extremely addictive and are a scourge that is killing thousands annually. The NFL lawsuit centers on informed consent and whether the players were cautioned about the dangers posed by these powerful pharmaceuticals.

The lawsuit against the NFL alleges incidents where unlabeled pills, Percocet and Motrin, were distributed to players in unmarked envelopes. The physical toll inflicted on footballs players and the influential role that team doctors play in their lives may make them uniquely susceptible to the dangers of opioids, but statistically they represent just the tip of the addiction iceberg.

It is not just NFL doctors passing out these pills like candy to injured players. In Alabama, which has the highest opioid prescription rate in the U.S., there are 143 prescriptions for every 100 people. Clearly, doctors bear a significant responsibility for creating this situation.

The extent of the addiction crisis is staggering. In 2015, there were more opioid users than smokers in America, a total of 27 million. Native Americans and Caucasians have the highest rate of death from opioids: 8.4 and 7.9 per 100,000 people. African Americans and Latinos have a death rate of 3.3 and 2.2 per 100,000. Addiction to opioids and heroin is costing the U.S. more than $193 billion each year.

It is inevitable that there is blowback for the overuse of opioid painkillers and it is no longer possible to ignore a calamity that has ruined and ended so many lives. Studies show that addiction ends up affecting over a quarter of those who use opioids for chronic non-cancer pain. Worse, 1 in 550 patients on opioid therapy dies from opioid-related causes within 2.5 years of their first prescription.

Perhaps this NFL lawsuit will help shed additional light on the dangers of powerful painkillers and the potential alternatives to these extremely dangerous drugs. That there is a huge problem has been acknowledged but to date the response has not been commensurate with the scope of the catastrophe. We need big pharma to acknowledge how dangerous their products are and make a point of minimizing their use. Natural and safer alternatives need to be promoted.

The most controversial and promising of these is medical cannabis. Medical marijuana has a long history as a natural analgesic. Its medicinal qualities are due to high amounts of cannabidiol (CBD), medicinal terpenes and flavonoids. Varieties of cannabis exist that are very low in tetrahydrocannabinol (THC) — the psychoactive component of marijuana that makes you feel “stoned” — and high in medicinal CBD.

How To Flush Marijuana Out Of Your System

pass drug test hero How To Flush Marijuana Out Of Your System

Sometimes it can be good to detox a bit and flush marijuana out of your system, and sometimes you have no choice because you really want that job you applied for and you know you’re going to be drug tested. Life’s rough, man. But although THC only stays in your system for a week, seven days exactly, passing a drug test can be more of a challenge for heavier smokers. However, there are ways to help you clean out your system, and it’s a good idea to brush up on the best ways to rid yourself of THC metabolites.

What are THC metabolites and what are drug screens looking for?

pass drug test lab analysis How To Flush Marijuana Out Of Your System

Drug test screenings typically involve testing your urine for metabolites.

Now what are metabolites? I’m so glad you asked. Metabolites are a side effect of a substance after its already been processed by your body. In this case, the guys in the white coats are going to be looking out for the THC metabolites in your system, or in more scientific terms, THC-COOH.

In order to know if you are ready for a drug test, you need to be able to figure out the amount of THC metabolites in your system and also know what the testing levels are for your drug screen. I know this sounds complicated but I’ll explain a bit further.

How long does marijuana stay in your system?

pass drug test smoking skeleton How To Flush Marijuana Out Of Your System

The half-life of THC metabolites is seven days. This means that every seven days, the amount of metabolites in your body will decrease by 50%. With this in mind, it can be assumed that your body will be rid of THC metabolites in about 3-4 weeks. However, it’s super important to note that these numbers can also depend on how much you smoke, how often you smoke, and how much you weigh.

Since THC is a fat soluble, which is why cannabis is great for deliciously fattening edibles, it can easily be stored in your fatty lipid tissue. As a result of this, your fat cells will release the THC metabolites into your bloodstream at a continuous rate, which is certainly not a good thing.

But guess what? You can still pass a drug test without being 100% free of THC metabolites. Since you still need your levels to be below the minimum amount of metabolites for the test, with a typical threshold being 50 mg/mL (whatever that means,) your test results will be negative and you’ll be home free!

Now I’m sure you’re probably thinking, “I don’t care about THC metabolites! I just want to know how to pass a drug test!” Chill out because I’m about lay down the facts.

How to pass a drug test

pass drug test thc molecule How To Flush Marijuana Out Of Your System

The basic method for passing a drug test is to dilute your urine just enough where, as I mentioned before, your levels will fall below the 50ng/ML limit.

There’s only one problem with that, though. The men in the white coats are keeping an eye out for fully diluted urine. Seriously, they know what you’re up to… With this in mind, you need to not only dilute your urine but to also cover up the fact that your urine is diluted. Ugh, talk about a catch-22.

So now you’re kind of annoyed because this kind of seems impossible? However, there are ways to mask diluted urine.

How to cover up diluted urine

pass drug test water glass How To Flush Marijuana Out Of Your System

There are several ways to dilute your urine. Hooray!

Let’s begin with water. Water is great for flushing out your system, but you shouldn’t feel the need to start chugging water weeks or days before your drug test. This only dilutes your urine for the time being so it’s pretty much a waste of time.

You’re better off drinking 3-4 liters of water throughout the day before you take your test, and then about 1.5-2 liters several hours before you leave to take your test. It’s important to know your limits, and really you should only be drinking a maximum of 2 liters. Note: drinking too much water can result in death, and that’s not the way you want to go out. Trust me.

After drinking a lot of water, your urine will be colorless and have low amounts of creatine. This is good, no? Eh, not so much.

By having colorless urine as well as low levels of creatine, the men in the white coats can easily see that you are trying waaay too hard to clean out your system, and we don’t want any of that.

How to do all of this and STILL pass your drug test

pass drug test pills How To Flush Marijuana Out Of Your System

There are two important substances that can still help you pull off this whole shebang– Vitamin B and creatine.

Vitamin B is important to take because it makes your urine yellow, therefore the men in the white coats won’t become suspicious. The most effective form of Vitamin B is either Vitamin B-2 or Vitamin B-12. It is recommended that you take 50-100 mg several hours before taking your drug test.

In addition to Vitamin B, creatine supplements can also help. Creatine, which is a chemical waste product that is already naturally in your body, can help the men in the white coats determine whether your urine is diluted or not.

Since creatine only has a half-life of three hours, you should take an above-average dose several hours before your test. You can find creatine supplements from any health food store, and as soon as creatine is broken down by your body, it will be completely flushed out of your system. Sweet.

But that’s not all folks. There are more ways to further guarantee that your system will be flushed of THC metabolites.

More tips for passing your drug test

greendetox How To Flush Marijuana Out Of Your System

Number one:  Avoid exercise for at least 24 hours before your test. For some of us, this isn’t too hard to accomplish since exercise and the word “avoid” often go hand in hand. But for all you gym rats out there, it’s best to avoid exercising because working out will only cause your THC metabolite levels to shoot up, and again, we don’t want any of that.

Number two: When you’re peeing into the cup, you should only provide the urine from the ‘middle’ of your urine stream. This is important to note because the first and last parts of your urine stream have the highest amounts of those evil metabolites.

Number three: Get your hands on some detox drinks. Detox drinks can be helpful but they only help to dilute your urine, which as we know, isn’t enough to pass your test. However, detox drinks also contain Vitamin B, as well as creatine, which also helps to hide the fact that your urine is diluted. Detox drinks, while convenient, can be a bit pricy, so keep that in mind as well.

I will leave you with a few notes. If you are a regular smoker or have a high level of fat, dilution may not be as effective and it may take longer to flush out your system. If this is the case, you can use the urine of a non-smoker but that’s on you if you choose to go down that road. Just know your facts and you should be just fine. Good luck!

How Long Does Weed Stay In Your System?

system featured How Long Does Weed Stay In Your System?

The amount of time that weed stays in your system depends on the user and how frequently they smoke. There are other factors involved, too, such as how it is being tested. THC binds the longest to the hair follicle and to saliva for the least amount of time. 

THC has a cumulative effect in the body and includes other factors such as the metabolic rate. However, as a general rule of thumb, this is how long cannabis stays in the system.

THC in urine

system times How Long Does Weed Stay In Your System?

The most common way to test for THC is in the urine because it is the cheapest method and has a long detection period. However, the length of time will vary depending on the frequency of use because of the cumulative effect of THC.

  • Someone who has smoked for the first time can test positive for THC for up to 8 days in urine.
  • Someone who smokes frequently can test positive for THC for up to 15 days in urine.
  • Someone who smokes heavily can test positive for THC for up to 30 days in urine.
  • Some heavy marijuana smokers have been tested positive for up to 45-90 days in urine after stopping smoking cannabis.

As a guide, if you´re a heavy smoker, chances are THC will remain in your urine for up to a month after stopping. This is also the most likely way you’ll be tested for weed in your system.

THC in saliva

system saliva How Long Does Weed Stay In Your System?

THC lasts the shortest time in the saliva. This is the method most often used by road police in checking for drugged drivers. It starts to test positive about 1 hour after smoking and can remain positive in saliva for up to 12 hours.

THC in hair

system hair How Long Does Weed Stay In Your System?

In the case of hair follicles, THC binds for the longest period of time. A single use of cannabis can test positive in the hair for up to 7 days, and most hair follicle tests are for a 90 day period. However, it is not always certain that cannabis actually binds to the hair follicle, so this method is hardly ever used.

THC in blood

system blood How Long Does Weed Stay In Your System?

THC is hardly ever measured from the blood because the metabolite of THC doesn´t bind to the blood for very long. As a result, testing cannabis in the blood only detects recent use.

How to pass a urine test

system urine test How Long Does Weed Stay In Your System?

Unfortunately, there´s no certain way to pass a urine test if you´re a heavy smoker. There are products that can be purchased solely for the purpose of cleansing urine, but their reliability is questionable.

The most scientific way to pass a urine test is to drink a lot of cranberry juice or a lot of fluids. Adding more water to the system will naturally dilute whatever is in your urine.

But the surest way to pass a urine test is to stick safely and generously to the time guidelines!

How long other chemicals stay in the system

While on the topic, it´s interesting to note how long other chemicals remain in the system after use.

  • Heroin can be detected in blood and saliva for up to 12 hours, and in urine for up to three days.
  • Amphetamines can be detected in blood and saliva for 12 hours after use and in the urine for 1-2 days after use.
  • A standard drink of alcohol can be detected in the body for only about 5 hours after use (the more that is consumed, the longer the it takes to metabolize, but is the shortest detection time of them all).


So many employers these days are testing their employees for drugs. However, it is easier to get away with having a problem with amphetamines than it is to be a cannabis smoker. Given the technology that is available, shouldn’t there be some leniency towards frequency of use with cannabis? It is legal now, after all. In fact, after legalization, the risk to the workforce if drug testing is not altered is extreme. It could result in a giant loss for the workforce in the USA.

Cannabis stays in the system longer than almost all other chemicals in the body because of it´s cumulative effect. However, everyone knows that you´re not necessarily high 12 hours after use. The best advice to smokers out there afraid of the ever prevalent urine test, stick to jobs that don´t require it!

Study shows THC removes Alzheimer plaque from the brain

Though just the beginning, these exploratory laboratory experiments have suggested that THC, one of the main chemical compounds in marijuana, can help prevent alzheimers by breaking down the memory-reducing plaque that would, otherwise, form in the brain.

The plaque is comprised of proteins, including beta-amyloid, and was reproduced at the Salk Institute for testing.

The researchers grew human neurons it the laboratory.  From there, they introduced the proteins, including beta-amyloid, and created the plaque build-up.

After this, they introduced THC and the results were astounding.

Not only did the THC break down the protein, but it caused the neurons to reduce in swelling.  It’s the swelling that can lead to additional protein build-up, so it seems that THC is working as a cleaner and a preventative.

“Although other studies have offered evidence that cannabinoids might be neuroprotective against the symptoms of Alzheimer’s, we believe our study is the first to demonstrate that cannabinoids affect both inflammation and amyloid beta accumulation in nerve cells,” says Salk Professor David Schubert, the senior author of the paper said in a statement.

Indeed, we have cannabinoid receptors all throughout our body.  Has the last 100 years of marijuana prohibition actually caused the development of alzheimers in humanity?  Are we that connected to the plant?  Obviously, if our body has built-in receptors for it; it has quite likely been a huge part of our evolution.  To have stripped it away may have done unjust damage.

Another study actually directly shows alzheimers is caused by a loss of cannabinoids, in which they explain the importance of cannabinoids in memory and learning.

More studies are welcome (and necessary) to identify a causal link between the THC and beta-amyloid reduction, including human trials.

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