Reasons Your Treatment For Hashimoto’s Thyroiditis And Hypothyroidism Isn’t Working

What Is Hashimoto’s Thyroiditis?

It is an autoimmune disease of the thyroid that has been increasing over time and is still largely undiagnosed and undertreated. The reason for this is that most primary care physicians only test for TSH so they miss a lot of pathologies when it comes to the thyroid gland, especially hypothyroidism and Hashimoto’s. HYPERthyroidism is more easily detected through TSH and the patient’s symptoms are specific to hyperthyroidism.

Patients with an underactive thyroid (HYPOthyroidism) and Hashimoto’s have symptoms that are common for many other disease processes such as chronic fatigue syndrome, Fibromyalgia, Depression, Anxiety, obesity, etc. These patients get missed for the proper diagnoses and instead, get treated for depression, told to lose weight, etc.

Causes And Symptoms Of Hashimoto’s Thyroiditis

The thyroid gland produces T4 which is largely inactive. This hormone is transported to the nucleus of every cell in the body. Here it is converted to T3. This transportation process into the nucleus and the actual conversion to T3 depends on the presence of plenty of ATP (cellular energy), trace minerals, and Iodine. Most Americans have poor cellular energy and deficient trace minerals due to long-standing malnourishment. It is no wonder that Hypothyroidism and Hashimoto’s is on the rise. In addition, the presence of heavy metals creates an autoimmune process in the body which can lead to Hashimoto’s disease. (antibodies against the thyroid).

The symptoms of Hashimoto’s and Hypothyroidism (with or without normal blood work) include chronic fatigue, depression, anxiety, thinning hair, inability to lose weight, high cholesterol, low sex drive, irregular periods, joint and muscle aches. By looking at this list, one can see how Hashimoto’s and subclinical hypothyroidism get missed.

Why Measuring Only TSH Doesn’t Work

Typically the physician that regularly sees their patients test for TSH only and not the thyroid markers themselves which are T4 and T3. TSH (thyroid stimulating hormone) is secreted by the pituitary gland when it detects low levels of T3 INSIDE THE HYPOTHALAMUS. Therefore, when TSH is elevated the patient is low on thyroid hormone. However, just measuring TSH without T4 and T3 is an inaccurate measure for the rest of the body as the hypothalamus lacks a regulatory protein that is present everywhere else. Because this inhibitory protein is not there, the hypothalamus has higher levels of T3 than anywhere else in the body. Therefore, patients who have under-active thyroid glands often have normal TSH and so the doctor does not prescribe thyroid hormone.

The increasing amount of undiagnosed patients who desperately need T3 is attributed to ordering the wrong blood tests. These patients are commonly misdiagnosed with something else like depression and chronic fatigue and forced to live in mystery as to why the doctor’s treatment isn’t working and why their blood tests are “normal”.

The Effects of Fluoride on the Thyroid Gland

There is a daunting amount of research studies showing that the widely acclaimed benefits on fluoride dental health are more imagined than real. My main concern however, is the effect of sustained fluoride intake on general health. Again, there is a huge body of research literature on this subject, freely available and in the public domain.

But this body of work was not considered by the York Review when their remit was changed from “Studies of the effects of fluoride on health” to “Studies on the effects of fluoridated water on health.” It is clearly evident that it was not considered by the BMA (Britsh Medical Association), British Dental Association (BDA), BFS (British Fluoridation Society) and FPHM, (Faculty for Public Health and Medicine) since they all insist, as in the briefing paper to Members of Parliament – that fluoridation is safe and non-injurious to health.

This is a public disgrace, I will now show by reviewing the damaging effects of fluoridation, with special reference to thyroid illness.

It has been known since the latter part of the 19th century that certain communities, notably in Argentina, India and Turkey were chronically ill, with premature ageing, arthritis, mental retardation, and infertility; and high levels of natural fluorides in the water were responsible. Not only was it clear that the fluoride was having a general effect on the health of the community, but in the early 1920s Goldemberg, working in Argentina showed that fluoride was displacing iodine; thus compounding the damage and rendering the community also hypothyroid from iodine deficiency.

Highly damaging to the thyroid gland

This was the basis of the research in the 1930s of May, Litzka, Gorlitzer von Mundy, who used fluoride preparations to treat over-active thyroid illness. Their patients either drank fluoridated water, swallowed fluoride pills or were bathed in fluoridated bath water; and their thyroid function was as a result, greatly depressed. The use in 1937 of fluorotyrosine for this purpose showed how effective this treatment was; but the effectiveness was difficult to predict and many patients suffered total thyroid loss. So it was given a new role and received a new name, Pardinon. It was marketed not for over-active thyroid disease but as a pesticide. (Note the manufacturer of fluorotyrosine was IG Farben who also made sarin, a gas used in World War II).

This bit of history illustrates the fact that fluorides are dangerous in general and in particular highly damaging to the thyroid gland, a matter to which I shall return shortly. While it is unlikely that it will be disputed that fluorides are toxic – let us be reminded that they are Schedule 2 Poisons under the Poisons Act 1972, the matter in dispute is the level of toxicity attributable to given amounts; in today’s context the degree of damage caused by given concentrations in the water supply. While admitting its toxicity, proponents rely on the fact that it is diluted and therefore, it is claimed, unlikely to have deleterious effects.

They could not be more mistaken

It seems to me that we must be aware of how fluoride does its damage. It is an enzyme poison. Enzymes are complex protein compounds that vastly speed up biological chemical reactions while themselves remaining unchanged. As we speak, there occurs in all of us a vast multitude of these reactions to maintain life and produce the energy to sustain it. The chains of amino acids that make up these complex proteins are linked by simple compounds called amides; and it is with these that fluorine molecules react, splitting and distorting them, thus damaging the enzymes and their activity. Let it be said at once, this effect can occur at extraordinary low concentrations; even lower than the one part per million which is the dilution proposed for fluoridation in our water supply.

The body can only eliminate half

Moreover, fluorides are cumulative and build up steadily with ingestion of fluoride from all sources, which include not just water but the air we breathe and the food we eat. The use of fluoride toothpaste in dental hygiene and the coating of teeth are further sources of substantial levels of fluoride intake. The body can only eliminate half of the total intake, which means that the older you are the more fluoride will have accumulated in your body. Inevitably this means the ageing population is particularly targeted. And even worse for the very young there is a major element of risk in baby formula made with fluoridated water. The extreme sensitivity of the very young to fluoride toxicity makes this unacceptable. Since there are so many sources of fluoride in our everyday living, it will prove impossible to maintain an average level of 1ppm as is suggested.

What is the result of these toxic effects?

First the immune system. The distortion of protein structure causes the immune proteins to fail to recognise body proteins, and so instigate an attack on them, which is Autoimmune Disease. Autoimmune diseases constitute a body of disease processes troubling many thousands of people: Rheumatoid Arthritis, Systemic Lupus Erythematosis, Asthma and Systemic Sclerosis are examples; but in my particular context today, thyroid antibodies will be produced which will cause Thyroiditis resulting in the common hypothyroid disease, Hashimoto’s Disease and the hyperthyroidism of Graves’ Disease.

Musculo Skeletal damage results further from the enzyme toxic effect; the collagen tissue of which muscles, tendons, ligaments and bones are made, is damaged. Rheumatoid illness, osteoporosis and deformation of bones inevitably follow. This toxic effect extends to the ameloblasts making tooth enamel, which is consequently weakened and then made brittle; and its visible appearance is, of course, dental fluorosis.

The enzyme poison effect extends to our genes; DNA cannot repair itself, and chromosomes are damaged. Work at the University of Missouri showed genital damage, targeting ovaries and testes. Also affected is inter uterine growth and development of the foetus, especially the nervous system. Increased incidence of Down’s Syndrome has been documented.

Fluorides are mutagenic. That is, they can cause the uncontrolled proliferation of cells we call cancer. This applies to cancer anywhere in the body; but bones are particularly picked out. The incidence of osteosarcoma in a study reporting in 1991 showed an unbelievable 50% increase. A report in 1955 in the New England Journal of Medicine showed a 400% increase in cancer of the thyroid in San Francisco during the period their water was fluoridated.

My particular concern is the effect of fluorides on the thyroid gland

Perhaps I may remind you about thyroid disease. The thyroid gland produces hormones which control our metabolism – the rate at which we burn our fuel. Deficiency is relatively common, much more than is generally accepted by many medical authorities: a figure of 1:4 or 1:3 by mid life is more likely. The illness is insidious in its onset and progression. People become tired, cold, overweight, depressed, constipated; they suffer arthritis, hair loss, infertility, atherosclerosis and chronic illness. Sadly, it is poorly diagnosed and poorly managed by very many doctors in this country.

What concerns me so deeply is that in concentrations as low as 1ppm, fluorides damage the thyroid system on 4 levels.

1. The enzyme manufacture of thyroid hormones within the thyroid gland itself. The process by which iodine is attached to the amino acid tyrosine and converted to the two significant thyroid hormones, thyroxine (T4) and liothyronine (T3), is slowed.

2. The stimulation of certain G proteins from the toxic effect of fluoride (whose function is to govern uptake of substances into each of the cells of the body), has the effect of switching off the uptake into the cell of the active thyroid hormone.

3. The thyroid control mechanism is compromised. The thyroid stimulating hormone output from the pituitary gland is inhibited by fluoride, thus reducing thyroid output of thyroid hormones.

4. Fluoride competes for the receptor sites on the thyroid gland which respond to the thyroid stimulating hormone; so that less of this hormone reaches the thyroid gland and so less thyroid hormone is manufactured.

These damaging effects, all of which occur with small concentrations of fluoride, have obvious and easily identifiable effects on thyroid status. The running down of thyroid hormone means a slow slide into hypothyroidism. Already the incidence of hypothyroidism is increasing as a result of other environmental toxins and pollutions together with wide spread nutritional deficiencies.

141 million Europeans are at risk

One further factor should give us deep anxiety. Professor Hume of Dundee, in his paper given earlier this year to the Novartis Foundation, pointed out that iodine deficiency is growing worldwide. There are 141 million Europeans are at risk; only 5 European countries are iodine sufficient. UK now falls into the marginal and focal category. Professor Hume recently produced figures to show that 40% of pregnant women in the Tayside region of Scotland were deficient by at least half of the iodine required for a normal pregnancy. A relatively high level of missing, decayed, filled teeth was noted in this non-fluoridated area, suggesting that the iodine deficiency was causing early hypothyroidism which interferes with the health of teeth. Dare one speculate on the result of now fluoridating the water?

Displaces iodine in the body

These figures would be worrying enough, since they mean that iodine deficiency, which results in hypothyroidism (thyroid hormone cannot be manufactured without iodine) is likely to affect huge numbers of people. What makes it infinitely worse, is that fluorine, being a halogen (chemically related to iodine), but very much more active, displaces iodine. So that the uptake of iodine is compromised by the ejection, as it were, of the iodine by fluorine. To condemn the entire population, already having marginal levels of iodine, to inevitable progressive failure of their thyroid system by fluoridating the water, borders on criminal lunacy.

I would like to place a scenario in front of those colleagues who favour fluoridation. A new pill is marketed. Some trials not all together satisfactory, nevertheless, show a striking improvement in dental caries. Unfortunately, it has been found to be thyrotoxic, mutagenic, immunosuppressive, cause arthritis and infertility in comparatively small doses over a relatively short period of time.

Do you think it should be marketed?

Fluoridation of the nation’s water supply will do little for our dental health; but will have catastrophic effects on our general health. We cannot, must not, dare not, subject our nation to this appalling risk.


L Goldemberg – La Semana Med 28:628 (1921) – cited in Wilson RH, DeEds F -“The Synergistic Action Of Thyroid On Fluoride Toxicity” Endocrinology 26:851 (1940).
G Litzka – “Die experimentellen Grundlagen der Behandlung des Morbus Basedow und der Hyperthyreose mittels Fluortyrosin” Med Wochenschr 63:1037-1040 (1937) (discusses the basis of the use of fluorides in anti-thyroid medication, documents activity on liver, inhibition of glycolysis, etc.).

W May – “Behandlung der Hypothyreosen einschlieblich des schweren genuinen Morbus Basedow mit Fluor” Klin Wochenschr 16: 562 – 564 (1937).

Sarin: (GB: isopropyl methylphosono-fluoridate) is a colorless, odorless volatile liquid, soluble in water, first synthesized at IG Farben in 1938. It kills mainly through inhalation.

Cyclosarin (GF) and Thiosarin are variants. Pennsylvania Department of

Sarin: (GB: CH3-P(=O)(-F)(-OCH(CH3)2)
Source: A FOA Briefing Book on Chemical Weapons Schrader, a chemist at IG Farben, was given the task of developing a pesticide. Two years later a phosphorus compound with extremely high toxicity was produced for the first time. IG Farben: “…the board of American IG Farben had three directors from the Federal Reserve Bank of New York, the most influential of the various Federal Reserve Banks. American IG Farben. also had interlocks with Standard Oil of New Jersey, Ford Motor Company, Bank of Manhattan (later to become the Chase Manhattan Bank), and AEG. (German General Electric) Source: Moody’s Manual of Investments; 1930, page 2149.”



10 Symptoms of Gluten Intolerance.

More than 55 diseases have been linked to gluten, the protein found in wheat, rye, and barley. It’s estimated that 99% of the people who have either gluten intolerance or celiac disease are never diagnosed. It is also estimated that as much as 15% of the US population is gluten intolerant. Could you be one of them? If you have any of the following symptoms it could be a sign that you have gluten intolerance:

1.) Digestive issues such as gas, bloating, diarrhea and even constipation. I see the constipation particularly in children after eating gluten.

2.) Keratosis Pilaris, (also known as ‘chicken skin’ on the back of your arms). This tends be as a result of a fatty acid deficiency and vitamin A deficiency secondary to fat-malabsorption caused by gluten damaging the gut.

3.) Fatigue, brain fog or feeling tired after eating a meal that contains gluten.

4.) Diagnosis of an autoimmune disease such as Hashimoto’s thyroiditisRheumatoid arthritis, Ulcerative colitis, Lupus, Psoriasis, Scleroderma or Multiple sclerosis.

5.) Neurologic symptoms such as dizziness or feeling of being off balance.

6.) Hormone imbalances such as PMS, PCOS or unexplained infertility.

7.) Migraine headaches.

8.) Diagnosis of chronic fatigue or fibromyalgia. These diagnoses simply indicate your conventional doctor cannot pin point the cause of your fatigue or pain.

9.) Inflammation, swelling or pain in your joints such as fingers, knees or hips.

10.) Mood issues such as anxiety, depression, mood swings and ADD.

Source: Eat Local Grown

Case report links artificial sweeteners, Hashimoto’s thyroiditis.

Recent literature suggest sugar-sweetened beverages increase the likelihood of incident obesity and diabetes. However, data from a case report presented here suggest that patients who consume a large amount of artificial sweeteners, such as Splenda, are also more likely to develop Hashimoto’s thyroiditis.

“We know that in the 20th and 21st century there is an increasing consumption of sugar substitutes. If you look at the literature in animal studies, it suggests it may cause obesity and some tumors. I found that this sugar substitute increases insulin levels in consumers and high insulin levels may be associated with obesity,” Issac Sachmechi, MD, FACE, FACP, clinical associate professor of medicine at Icahn School of Medicine at Mount Sinai; and chief of endocrinology at Queens Hospital Center, said during a press conference.

According to abstract data, Sachmechi treated a woman aged 52 years with a history of high intake of artificial sweeteners and a diagnosis of Hashimoto’s hypothyroidism in 2008. The patient’s TSH measured 12.2 mIU/L, free T4was 0.5 ng/dL and antithyroid peroxidase antibodies (TPOAb) were 196 IU/mL.

Sachmechi treated the patient with levothyroxine 0.75 mg per day and normalized her TSH (between 1.23 mIU/L and 2.16 mIU/L) over 3 years of treatment. Subsequently, the patient stopped ingesting the sweeteners in February 2012 due to weight gain.

This resulted in a TSH level of 0.005 mIU/L, where it remained low despite a decrease of levothyroxine dose to 0.05 mg per day. Furthermore, a complete discontinuation of the drug was followed with normal TSH and anti-TPOAb <20 IU/mL, TSI of 113% and TBII <6%.

Sachmechi reported that the patient continued to be clinically euthyroid without further treatment during subsequent follow-up visits.

“We know there is an increased prevalence of Hashimoto’s hypothyroidism and differentiated thyroid cancer without currently known etiologies. “It is possible that the artificial sweetness may have a roll in this,” Sachmechi said.

“We plan to do a study looking at the use of artificial sweetness in large number patients with diagnosis of Hashimoto’s hypothyroidism and patients with well differentiated thyroid cancer to see if we find any coloration consumption of artificial sweetness and those thyroid diseases.”

These data indicate eliminating artificial sweeteners from the diet can benefit patients with thyroid disease. Sachmechi told Endocrine Today that a study is underway to confirm these findings in a larger cohort. – by Samantha Costa

Source: Endocrine Today


Papillary thyroid carcinoma linked to Hashimoto’s thyroiditis.


Data from a recent meta-analysis demonstrate that papillary thyroid cancer is significantly associated with pathologically confirmed Hashimoto’s thyroiditis, despite decades of controversy.

Researchers from Korea University Ansan Hospital used citation databases to search the literature for relevant studies; they found 38 eligible studies that included 10,648 patients with papillary thyroid carcinoma (PTC). Of those, 23.2% had histologically proven Hashimoto’s thyroiditis.

According to the analysis, Compared with benign thyroid diseases and other carcinomas, Hashimoto’s thyroiditis was more commonly seen in PTC (OR=2.4 vs. 2.8; P<.001).

Additionally, cases of PTC with existing Hashimoto’s thyroiditis were significantly linked to female patients (OR=2.7; P<.001); multifocal involvement (OR=1.5; P=.010); no extrathyroidal extension (OR=1.3; P=.002); and no lymph node metastasis (OR=1.3; P=.041), the researchers wrote. The long recurrence-free survival among patients with both PTC and Hashimoto’s thyroiditis also was significant (HR=0.6; P=.001).

“Our meta-analysis showed that PTC is significantly associated with pathologically confirmed [Hashimoto’s thyroiditis]. PTC patients with [Hashimoto’s thyroiditis] have favorable clinicopathologic characteristics compared with PTCs without [Hashimoto’s thyroiditis]. However, patients with [Hashimoto’s thyroiditis] need to be carefully monitored for the development of PTC,” they wrote.

Source: Endocrine Today.