Understanding the many benefits of cannabis in cancer treatment


Image: Understanding the many benefits of cannabis in cancer treatment

A cancer diagnosis is both devastating and terrifying. Patients are almost always directed towards conventional cancer treatments like surgery, chemotherapy and radiation, and are made to feel that any other, more “natural” treatments are not only ineffective but dangerous.

The truth is, however, that mainstream cancer treatments wreak havoc on the body, leaving it defenseless against disease and breaking it down at the exact time when it needs to be as strong as possible. With its less than impressive success rate of between 2 and 4 percent, along with its devastating effects on the body, it is unsurprising that three out of every four doctors say they would refuse chemotherapy as a treatment option if they themselves became ill.

While doctors like to promote the idea that there are no treatments scientifically proven to work besides the usual surgery/chemotherapy/radiation regimen, the truth is there is a strong body of evidence that many natural, non-invasive treatments are effective in the fight against cancer. One of the most well-researched and solidly proven of all these natural medicines is cannabis.

The miraculous power of cannabinoids

As noted by Dr. Mark Sircus, writing for Green Med Info, there is no confusion about whether marijuana is an effective cancer treatment. Cannabis has been scientifically proven to kill cancer cells without the devastating and body weakening effects of conventional cancer treatments.

The marijuana plant contains about 113 powerful chemical compounds known as cannabinoids. The most well-known of these compounds are tetrahydrocannabinol (THC) – the chemical that induces marijuana’s “high” – and cannabidiol – a non-psychoactive compound which has been extensively studied as a cure for many diseases.

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These and other cannabinoids are what make marijuana such a potent anti-cancer treatment, as reported by Green Med Info:

Cannabinoids are found to exert their anti-cancer effects in a number of ways and in a variety of tissues.

  • Triggering cell death, through a mechanism called apoptosis
  • Stopping cells from dividing
  • Preventing new blood vessels from growing into tumors
  • Reducing the chances of cancer cells spreading through the body, by stopping cells from moving or invading neighboring tissue
  • Speeding up the cell’s internal ‘waste disposal machine’ – a process known as autophagy – which can lead to cell death

All these effects are thought to be caused by cannabinoids locking onto the CB1 and CB2 cannabinoid receptors. Almost daily we are seeing new or confirming evidence that Cannibinoids can be used to great benefit in cancer treatment of many types.

https://www.brighteon.com/embed/5849729304001

What the science says

Scientific studies published in a host of peer-reviewed journals have confirmed marijuana’s powerful ability to fight breast, lung, ovarian, pancreatic, prostate and other cancers.

A meta-analysis of over 100 published studies, performed by researchers from Germany’s Rostock University Medical Centre, concluded that cannabis both boosts immunity and fights cancer.

The Daily Mail reported:

Scientists are calling for more studies to be done on humans after studying the cancer-fighting effects of chemicals in the drug.

Studies suggest chemicals called phytocannabinoids could stop cancer cells multiplying and spreading, block the blood supply to tumors, and reduce cancer’s ability to survive chemotherapy. …

The new research review admits cannabis has ‘anti-cancer effects’ and says more research needs to be done in real patients to confirm the findings.

It takes real courage to receive a cancer diagnosis and decide not to follow mainstream advice but seek alternative treatments. But even for those who choose to receive conventional cancer treatments like radiation and chemotherapy, cannabis can still be an important part of their overall wellness plan. As Dr. Sircus admonishes, “Every cancer patient and every oncologist should put medical marijuana on their treatment maps.”

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2018 Nobel Prize in Physiology or Medicine awarded to James P. Allison and Tasuku Honjo


Allison and Honjo were jointly awarded the 2018 Nobel Prize in Physiology or Medicine “for their discovery of cancer therapy by inhibition of negative immune regulation.” Their discoveries will fundamentally change the way doctors manage cancer treatment.

What are car T cell therapies in cancer treatment, and why is there so much buzz about it nowadays?


For a long time, the cancer treatment universe was restricted to 4 modalities, in particular Surgery, Radiation, Chemotherapy and Targeted Drug Treatments. Of late, we have seen the expansion of a fifth front in the fight against cancer, called Immunotherapy. Researchers have been endeavoring to create approaches to prepare the human immune system to battle cancer cells, similar to how they eliminate germs in trifling issues such as the common cold.

When we become ill with the common cold, our immune system attacks the infectious germs and executes them, viably curing us. What is at work here are a sort of cells present in our blood called T-cells. T-cells have the one of a kind capacity to recognize affected cells, lock on to them and kill them.

In a CAR T-cell treatment, a patient’s T-cells are designed, so that they attach themselves to cancer cells and destroy them. Such T-cells are extracted from the patient’s own blood, and are built in a lab to identify particular proteins (or antigens) present inside cancer cells. Then, once these cells increase in adequate numbers, they are infused once more into the patient’s circulation system. Once in the body, they start targeting cancer cells.

The utilization of Car T-cell treatments had been constrained to clinical trials till recently. In these trials, numerous patients in advanced stages of cancer have encountered positive outcomes. Numerous such trials included patients experiencing advanced ALL (Acute Lymphoblastic Leukemia) with limited treatment alternatives. Most patients experienced 100% remission, and remained this way for prolonged periods of time. Comparable promising outcomes have been seen in the case of lymphoma patients. Some of these treatments have been approved for treatment in certain leukemias and few solid tumours.

While the symptoms of such medicines can be perilous, the medical science has developed practical protections against such impacts, with supportive treatments. Car T-cell treatments appear to have immense potential, however given the dynamic nature of cancer mutations, further investigation is required to standardize it and make it accessible to patients all around. Numerous labs around the globe are right now testing these treatments not only for blood cancer but also solid tumors, such as pancreatic and brain tumours. Given the measure of intrigue the field has produced among scientists around the world, it is likely that the following decade will be transformative in characterizing the cancer treatment paradigm.

 

5 Stem Cell Innovations From The Past Year, From Cancer Treatment To Diabetes Therapy


Ten years ago, the topic of stem cells was shrouded in mystery, but now they’re at the forefront of some of the latest innovations in biology and medicine. Stem cells have yet to change into a specific type of cell, such as a brain or skin cell. As a result, doctors can manipulate them into, well, any type of cell they want. However, the way that stem cells are being manipulated is anything but simple. Here is a run-down of five of the most fascinating stem cell innovations from the past year.

stem-cell

Stem Cells From Baby Teeth

Teeth are necessary for helping us chew our food, but once they fall out. they’re useless; or not? The practice of tooth saving, or cryopreserving, has gained popularity, and for good reason. New research suggests the stem cells found in the pulp of teeth could be used to help people regrow their adult teeth (rather than needing a crown or dentures), and may even have other potentially life-saving regenerative medical benefits, CNN reported.

While still in its early stages, the idea behind tooth preservation is that no other stem cells work better than your own. By saving your baby teeth, or adult teeth that need to be removed through surgery, you may later harvest stem cells that may be used to fight certain cancers or even as therapy for brain injuries.

 

Babies Cured of Leukemia

Leukemia is a type of cancer of the blood, and it starts in the bone marrow, which is where our stem cells originate. Traditional leukemia treatment involves a combination of chemotherapy and radiotherapy, but earlier this year doctors at London’s Great Ormond Street hospital believe they cured two babies of leukemia using a new stem cell treatment, Technology Review reported.

The treatment involves taking stem cells from a donor and genetically altering them before injecting them into a patient. These cells are altered so that they are able to attack cancer.

According to Euro Stem Cell, in traditional stem cell treatments for leukemia patients, cells are taken from donors and then transformed into special cancer-fighting cells; however, this process takes time — something many seriously ill cancer patients do not have. The Great Ormond Street team hopes that taking stem cells from donors and genetically altering them into hundreds of doses of cancer-fighting cells will create a reserve of treatments available to anyone who needs them.

Helping Diabetes Patients

According to a study released last year, researchers at Washington University School of Medicine in St. Louis and Harvard University were able to change stem cells derived from the skin of diabetes patients into insulin-secreting cells.

Type 1 diabetics cannot create insulin, which is why patients must inject themselves with this hormone throughout the day. Although this new treatment is still being researched, injecting these stem-cell derived insulin-secreting cells into diabetes patients could control blood sugar without the need for medication.

Regenerate Brains of Brain-Dead Patients

Stem cells theoretically can be turned into any type of cell, and as suggested by a 2016 project, this includes brain cells. The project, headed by a team at Bioquark Inc and Revita Life Science India, intends to regenerate the brain cells of 20 patients that have been declared brain dead from a traumatic brain injury to see whether or not their central nervous systems can be restored, The Telegraph reported.

The team hope the stem cells will grow into new brain cells to replace the dead cells in the brain. While the treatment wouldn’t restore these brain-dead patients back to life, the research may lead the way to new therapies for patients in vegetative states or with certain degenerative conditions.

Brain Balls

Brain balls are basically what they sound like; tiny little brains in the shape of balls. According to Wired, they are one of the newest innovations in stem cell research and could hold the answer to treating a variety of medical conditions.

These brain balls are created by coaxing a bunch of stem cells into becoming brain cells, and then using these “mini brains” to better understand how different diseases affect the brain. For example, according to Wired, these brain balls are ideal for studying conditions such as the Zika virus as scientists can see what’s actually happening in an infected brain, but on a much smaller scale.

Metabolically Supported Therapies for the Improvement of Cancer Treatment



Story at-a-glance
  • Oncologists in Turkey who aren’t under the same U.S. restrictions, are using a stacked ketogenic treatment protocol that is showing shocking remissions in many stage 4 cancer patients
  • By using metabolic support strategies such as ketogenic diet and fasting, a minimal dose of chemotherapy can be used, thereby eliminating many of the side effects and risks of treatment while actually improving outcomes
  • Stage 4 pancreatic cancer patients have a life expectancy of six months. Yet metabolically supported chemotherapy was able to induce complete remission even in patients with this advanced stage disease

Each and every day, more than 1,600 people prematurely die from cancer in the United States alone and 20,000 worldwide. While the situation can sometimes seem hopeless, there are effective ways to prevent becoming another statistic.

And, as you will soon learn, even late-stage cancer patients have cause for new hope these days.

In this interview, Travis Christofferson, author of “Tripping Over the Truth: How the Metabolic Theory of Cancer is Overturning One of Medicine’s Most Entrenched Paradigms,” and Dr. Abdul Kadir Slocum from the ChemoThermia Oncology Center in Turkey.

They present data from one of the first  studies documenting the effectiveness of metabolic therapies and nutritional ketosis in the treatment of advanced stages of cancer.

“I’m very excited for this data to be presented,” Christofferson says. “[Cancer] diagnosis has gone up from 1 in 4 to 1 in 3 and is heading toward 1 in 2 … It’s set to surpass heart disease as the No. 1 killer in the Western world by 2020 …

We’ve been treating this disease a long time. Nixon signed the Cancer Act in 1971 … Radiation and surgery have been around for over 100 years. Cytotoxic chemotherapy was developed right after World War II. [Yet] death rates from treatment have barely budged since the 1950s.”

The War on Cancer Has Been Lost Many Times Over

In the mid-1970s, scientists believed they finally understood the molecular basis of cancer. The reigning hypothesis was that cancer was caused by sequential mutations to key oncogenes, which could then be precisely targeted using gene-based therapies. This ushered in the era of targeted therapy.

Alas, targeted cancer drugs have been a bitter disappointment. They barely moved the needle on cancer death rates. Globally, $91 billion was spent on oncology in 2013. In 2014, no cancer drug was approved costing less than $100,000 for a course treatment.

In 2015, eight drugs were approved that cost over $120,000 each for a course of treatment. As noted by Christofferson, this trajectory will eventually bankrupt the health care system. Adding insult to injury, these drugs have marginal efficacy at best.

Consider Tarceva, for example. This cancer drug was approved about 10 years ago. It has significant side effects, it’s expensive, and boosts median survival for pancreatic cancer patients by a mere 10 DAYS!

“In the meantime, we have these non-patentable therapies sitting on the sidelines that could potentially be game changers for cancer, but they cannot get the billion-dollar backing to push through these huge trials to get the burden of proof to where the oncology community will actually incorporate them,” Christofferson says.

“We have all these interesting metabolic therapies. We have repurposed drugs that we could use. The oppressive regulatory environment just needs to be loosened so we can surmount the burden of proof, Phase 1, Phase 2 data, if we have good objective response.

If they’re safe — most of these drugs and therapies are extremely safe — that should be good enough.

In the epilogue in my book, I ask the question, ‘What would it look like today if we had a less onerous regulatory environment like they did in the ’70s, and good oncologists were allowed to … try some of these therapies in the clinic and see what happens?’

That’s why I’m so happy we have Slocum here, because he’s given us the first glimpse of what metabolic therapies will look like when they’re incorporated into the clinic.”

Turkish Oncologists Apply the Metabolic Theory of Cancer

Slocum, who is originally from the U.S. but grew up and completed his medical training in Istanbul, Turkey, is part of a four-member medical team at ChemoThermia Oncology Center.1

The senior person of the team, professor Bulent Berkarda, was the first medical oncologist in Turkey. Educated in the U.S., Berkarda founded the first Department of Medical Oncology of Turkey at Istanbul University in 1974 and has now been practicing oncology for over 40 years.

Together with Berkarda, the other medical oncologist of the team, assistant professor Mehmet Salih İyikesici completed his education in the leading medical schools of Turkey.

“We started as a team back in 2010, asking the question, ‘How can we help our patients in a better way? What can we add to our standard treatment protocols?’ Slocum says. “In the last six years, we started applying the [metabolic] therapies and seeing how our patients respond.

Now, for the last two years or so, we’re doing retrospective analyses of our patients, publishing our treatment outcomes and sharing the remarkable outcomes we were able to achieve by combining metabolic therapies with standard conventional protocols.”

The treatment protocol at ChemoThermia Oncology Center includes:

  • Metabolically supported chemotherapy
  • Hyperthermia
  • Hyperbaric oxygen therapy
  • Glycolysis inhibitors, especially 2-deoxyglucose (2-DG) and dichloroacetate (DCA)
  • Ketogenic diet with phytopharmaceutical supplements

Metabolically Supported Chemotherapy

Metabolically-supported chemotherapy involves applying chemotherapy with a variety of interventions to support its effectiveness.

At the center, all oncology patients are put on a ketogenic diet, which creates metabolic stress on the cancer cells. Then, prior to administering the chemo, the patient will do a 14-hour fast, which further increases the metabolic stress on the cancer cells.

The patients will typically have a blood glucose level around 80 milligrams per deciliter (mg/dL) at this point. They then apply glycolysis inhibitors to inhibit the glycolysis pathway in the cancer cells, which creates a terrific amount of metabolic stress, as the cancer cells are already starved of glucose.

Insulin is then applied to lower the blood glucose levels to around 50 or 60 mg/dL, to cause mild hypoglycemia. At that point, chemotherapy is applied.

“[T]his increases the efficacy of chemotherapy in a tremendous way,” Slocum says. “We’ve been applying this for the last seven years now. It’s an improved version of insulin potentiation therapy (IPT). IPT is known for many years now, but it’s not too widely applied.

Our version of chemotherapy is actually an improved and a much more effective version of IPT because it combines the metabolic theory with the IPT. Metabolically supported chemotherapy is just a different way to apply conventional protocols. We have seen that it increases the effectiveness of the standard chemotherapy regimes. This way, it gives us the option to apply lower doses, see much lower side effects, but much [better] outcomes.”

As in the U.S., Turkish oncologists are bound by “standard of care” treatment protocols, which includes chemotherapy. As noted by Slocum, “according to the current regime worldwide … the patient, even in Turkey, must receive what’s written in the guidelines. If you go against the guidelines and if the patient doesn’t receive the standard of care, which is chemotherapy, then you’re in trouble.” They essentially get around this by just using the lowest dose possible that’s written in guidelines.

The upshot of this metabolic approach is that a far lower dose of chemotherapy can be effectively used, thereby lowering the risk of side effects. In the days following chemotherapy, hyperthermia and hyperbaric oxygen therapy is applied, plus a daily infusion of glycolysis inhibitor therapies with high-dose vitamin C (50 grams) and dimethyl sulfoxide (DMSO).

Complete Response for Stage 3 Rectal Cancer

In the team’s first publication in 2016, they reported complete response for stage 3 rectal cancer. The standard of care for rectal cancer and the only curative option has been surgery or chemo-radiotherapy followed by surgery. In this case, they used metabolically supported chemotherapy, radiotherapy and hyperthermia. No surgery was necessary.

“The reason we published that was to explain what metabolically supported chemotherapy is and show how effective it can be,” Slocum says. “The patient we published was 81 years old back then.

Generally, in an 81-year-old patient you won’t be able to apply standard chemotherapy regimens. She won’t be able to tolerate it. By the means of the way we apply chemotherapy, this patient was able to receive chemotherapy at lower doses in a metabolically supported fashion, together with radiotherapy and hyperthermia.”

In the video, Slocum shows the initial positron emission tomography-computed tomography (PET-CT) scan of this patient. The patient had a 5.5 centimeter large rectal tumor. Three months later, the tumor was in full remission.

“This publication mainly showed that chemotherapy, when applied in a metabolically supported fashion, can be applied to patients who normally can’t receive treatment. Also, when it’s applied with increased efficacy, responses that aren’t normal, generally, which is a complete response in this stage of a disease, can be achieved by the means of metabolic support.”

Case Series on Pancreatic Cancer

The second paper published last year was a case series of 33 patients with stage 3 and 4 pancreatic adenocarcinoma (pancreatic cancer) — one of the most aggressive and deadly cancers known. It was a retrospective analysis of patients treated at the clinic between 2011 and 2015. Eighty-one percent of these patients had stage 4 disease when the treatment began, and many of them also had large scale liver metastasis.

Generally, if a patient has stage 4 pancreatic adenocarcinoma, their life expectancy is about six months, at most 10 months. If they have large-scale liver metastasis, death typically occurs within weeks or months. Yet despite the majority being end-stage advanced patients, they responded remarkably well to the treatment.

Here, the standard conventional protocol using either gemcitabine-based chemotherapy or folfirinox was again applied in a metabolically supported fashion, together with hyperthermia, hyperbaric oxygen therapy, the ketogenic diet, supplements and glycolysis inhibitors.

When the paper was published in 2016, 54 percent of these patients were still alive, and most are still receiving follow-up treatments to this day. Following the conventional protocol, the expected median survival time for the gemcitabine-based protocol is 6.2 months. For the folfirinox regimen it’s 11.1 months. Using a metabolically supported protocol, the median survival time shot up to 20 months — and 54 percent of the patients are still alive today.

“The one-year survival rate for gemcitabine-based protocol is 20 percent. For folfirinox, it’s 48 percent. We’ve seen in our metabolically supported chemotherapy regimen, [survival rate] is 82.5 percent. This shows how effective metabolic support can change the outcomes of treatments and how effective these kinds of treatments can be,” Slocum says.

“As all of us know, the scariest cancer diagnosis is pancreatic cancer. Currently in our regimens, we’re seeing amazing outcomes. It’s so exciting to see how small differences can change these patients’ lives so much.”

Case Series on Stage 4 Lung Cancer

Next, the team will be publishing a paper on stage 4 non-small cell lung cancer. Here, they applied a chemotherapy regimen using carboplatin and paclitaxel. Large-scale clinical trials show an expected survival time of six to 11 months. Moreover, stage 4 patients typically cannot tolerate conventional chemo regimens so no large-scale studies have focused on such late-stage patients.

Using the metabolically supported protocol, however, all of the 44 patients in the study were able to receive treatment, and the overall survival time is 43.4 months — that’s more than 400 percent longer than the longest survival time mentioned in any standard chemotherapy regimen.

“This is a dramatic result, even though the patient group we had had more advanced disease and had poor performance status,” Slocum notes. “[P]atients who normally were sent home to just wait for the end, to die, and also patients that won’t be able to receive treatment … can respond [well] to treatment … The advantage of metabolic treatments is that they’re generally not toxic at all. They support the general wellbeing of the patient while also treating the disease.”

Survival Rates for Late Stage, Advanced Cancers Dramatically Improve With Metabolic Therapies

In the video, Dr. Slocum shows PET scans and reviews a number of different patient cases, showing the remarkable response of patients with advanced cancer of the rectum, pancreas, stomach, lung and breast.

This is, to the best of my knowledge, the first time all of this data has been publicly shared. It’s really exciting to reveal to the world the shocking effectiveness of what Thomas Seyfried, Ph.D., has been speaking about for some time now. And, if you’re stage 1 or 2, your cancer is going to be far easier to treat. The results for early stage cancers are likely to be beyond phenomenal.

“We hope that this kind of treatment will be the standard of care in the upcoming years. We are all trying to share what would work and how we’re achieving these kinds of results,” Slocum says. “Other clinics and other physicians will also hopefully start doing similar therapies.”

Christofferson adds:

“[Thomas] Seyfried [Ph.D., a leading expert and researcher in the field of cancer metabolism and nutritional ketosis] and Slocum met in Tampa. They’ve started a collaboration … Hopefully a year from now, when we talk about these shocking outcomes, they’re even more shocking.

Just to summarize, [Slocum’s] upcoming stage 4 lung cancer paper is incredible … A certain percentage of them aren’t going to make it no matter what, but if they can get through this metabolic protocol, the median survival would increase 400 percent.

That’s incredible. This stuff basically is free. It just took somebody motivated enough to do this. I mean 2-deoxyglucose (2-DG) is expensive, but ketogenic diet is free. It just takes work. I couldn’t be happier that this data is coming to life.”

Discipline Is Required When Your Life Is in Your Own Hands

It goes without saying that when using metabolic therapies, the patient carries a significant responsibility for their own outcome. The doctors are not going to cook your food, force you to take supplements or withhold food when it’s time to fast. You have to be very diligent and disciplined in following the specified regimen. As noted by Slocum, when patients don’t respond as well as expected, probing will usually reveal the problem — they didn’t follow the diet, for example.

Essentially, if you have a life-threatening condition like stage 4 cancer, you need to be a bit obsessive compulsive and follow the regimen to the letter. You cannot veer from the protocol if you expect to achieve these kinds of results. You really need to remain in nutritional ketosis. That said, if you’re merely seeking to optimize your health or slow down the aging process, cycling through “feast and famine” — opposed to continuously remaining in nutritional ketosis — appears to be a better approach.

Nutritional ketosis is a powerful intervention, as Slocum’s team has shown. But if you do it continuously, it can actually be highly counterproductive. You need to have days where you eat more net carbs and more protein, especially with strength training, to prevent sarcopenia that is common in cancer.

This is because when cancer cells are deprived of glucose they have the ability to break down muscle tissue to extract glutamine. Interestingly, Seyfried is working with a glutamine inhibitor called DON to prevent this from happening, thereby making the therapy even more effective.

It is important to understand that the “metabolic magic” actually occurs during that refeeding phase when net carbs and protein are increased, which increases muscle growth. After a day or two, you then cycle back into nutritional ketosis.  Typically, this is done once a week. To a degree, Slocum uses this technique on cancer patients as well, although they’re only allowed to eat higher amounts of net carbs once every two or three weeks, on the day they receive chemo.

“As an example, patients come and they’re on a ketogenic diet. When they come in for chemotherapy after a 14-hour fast, then [we] apply glycolysis inhibitors to increase metabolic stress even more and insulin to lower the glucose and then apply chemotherapy.

After applying chemotherapy, on the day of chemotherapy, they are able to eat whatever they want, especially because of the mild hypoglycemia caused by supplying insulin. The day of chemotherapy is when they get as much carbohydrates as they want … We also do intermittent fasting [for a minimum of 14 hours] every other week or so. It seems to be effective.”

More Information

The ChemoThermia Oncology Center treats many international patients, including people from the U.S. and Canada. The center also has published protocols your oncologist could make use of, regardless of where you live.

“We hope there will be physicians open to applying similar regimens to ours,” Slocum says. “But a lot of patients who aren’t able to come to our clinic, they can [still] do it. They first have to go on a ketogenic diet, which is very effective. Together with that, they should go to their chemotherapy in a fasting state, as long as they can stand it — a minimum of 12 hours. We generally recommend a 14-hour fast. The longer … the better.”

Ideally, a reduced amount of the chemotherapeutic agents would then be used. While the amount varies according to your diagnosis and condition, the center has included dose range recommendations in their publications. Typically, the lowest recommended dose is given, which will significantly reduce or avoid most of the complications associated with chemotherapy.

“I hope people out there can see how effective metabolic therapies can be and how they can enhance conventional treatment protocols also. I encourage clinicians out there to ask similar questions to us, to read the literature and start applying similar therapies to ours,” Slocum says.

Christofferson adds:

“What I would like to say is [that] patients who are confused by the ketogenic diet often don’t know the difference between protein and carbohydrate. That’s where they often get tripped up, because they’re not sure what a carbohydrate is. Companies are stepping into this fray, making prepackaged ketogenic meals for cancer patients that take out the guesswork.

The ones I’ve seen are really well done by gourmet chefs and [use] real ingredients. That’s another option. There’s enough on patients’ plates to begin with … That’s going to take a lot of the guesswork out for patients, I think.”

To learn more about nutritional ketosis and the metabolic theory of cancer, I highly recommend listening to the interview I did with Christofferson last year, and to read his book, “Tripping Over the Truth,” which provides the background as to why and how this therapy works, and why the conventional approach to cancer is fatally flawed.

If you’re beyond that point and really want to implement this kind of metabolic therapy, I highly recommend preordering a copy of new book, “Fat for Fuel,” which gives you all the details on how to do that. Anyone that preorders it will have access to my recent 2017 lecture that I have given at several events. Normally these lectures are never posted online. Incidentally, Christofferson was one of the experts who helped edit my book and actually wrote a section on Dr. Rosedale’s work. I’m grateful for all his assistance.

Besides the information in the book, you’ll also find many collaborative supports, including a nine-hour-long free video series that we hope to launch in early May. Miriam Kalamian is also developing a certification course to go along with it through the American College of Nutrition, to have more qualified therapists out there.

This certification will teach any qualified clinician — primarily certified clinical nutritionists but also physicians — how to practically implement nutritional ketosis. Eventually, I expect there will be a virtual army of clinicians available to assist patients with this kind of protocol. Hopefully, at that point we’ll finally start making a dent in cancer statistics.

Watch the video. URL:

Source:mercola.com

Atrocious State of Cancer Treatment in the U.S.



Story at-a-glance

  • Despite a decades-long war on cancer, and the “most advanced” treatments known to 21st-century oncologists, many cancer diagnoses remain a death sentence
  • Patient requests for possible experimental, natural or outside-the-box treatments are typically denied by oncologists who refuse to deviate from the hospital’s standard protocol
  • The film “Surviving Terminal Cancer” follows the story of those who have survived terminal cancer by bucking the system and taking their health and cancer treatment into their own hands

Being diagnosed with glioblastoma multiforme, a type of brain tumor, is considered a death sentence by modern medicine.

Despite a decades-long war on cancer, and the “most advanced” treatments known to 21st century oncologists, people who develop this aggressive, fast-growing cancer are given a prognosis of about 15 months to live — if they’re lucky.

Aggressive treatment, including surgery, radiation and chemotherapy, is often started, even though oncologists know it won’t cure the disease. If you ever find yourself in this type of nightmarish scenario, you can imagine the desperation you would feel to find something, anything, that might offer hope.

Most people turn to their oncologists or neurosurgeons with such requests for possible experimental or outside-the-box treatments, but you’re unlikely to receive any help that deviates from the hospital’s standard protocol.

It’s not that such treatment options don’t exist; they do. The problem is that the oncologist can’t, or won’t, prescribe them. To do so would risk his or her reputation and even medical license, should you decide to sue.

The film interviews a number of oncologists that carefully describe their predicament. But the problem is even larger than this. Modern cancer care is not set up to treat you, an individual. Their primary goal is to validate experimental therapies for future cancer patients many years down the road.

Due to regulatory red tape, drug-company greed, failures in the scientific process and lack of a universal will to do what’s best for each and every patient, modern cancer care fails an unacceptable percentage of the time.

As Albert Einstein said, the definition of insanity is doing the same thing over and over again and expecting different results. This describes modern cancer treatment in a nutshell.

How One Man Survived Terminal Cancer

Ben Williams, Ph.D., professor emeritus of Experimental Psychology at University of California, San Diego, shouldn’t be here today. He should be one of the statistics — 1 of the more than 15,000 people who die from glioblastoma multiforme in the U.S. every year.1

Yet, he’s alive — 19 years after his initial glioblastoma multiforme diagnosis. His survival was brushed off as a rare fluke by his doctors, but Williams believes otherwise.

In his book “Surviving Terminal Cancer: Clinical Trials, Drug Cocktails, and Other Treatments Your Oncologist Won’t Tell You About,” he details the multi-faceted strategy he used to overcome the disease. You can hear him tell his story first-hand in the film “Surviving Terminal Cancer,” above.

It’s becoming increasingly clear that in order to outsmart cancer, you’ve got to attack it from multiple angles, especially in the case of complex brain cancer. And that’s what Williams did.

He described a mushroom extract that’s used routinely to treat cancer in Japan. It has zero toxicity, but it’s not even mentioned in the U.S.

He did his own research, finding out about the potential to use existing non-cancer medications off label to treat the deadly disease. Once a patent expires on a drug, its potential to rake in major profits plummets. As such, drug companies typically abandon them in favor of newer, more profitable pursuits.

Abandoned Drugs Show Promise but Oncologists Won’t Prescribe Them

Some of these abandoned drugs have shown promise for glioblastoma multiforme, but they’re not offered to U.S. patients. While I’m not in favor of over-prescribing medications, if you’re facing a deadly prognosis you’re probably willing to risk the side effects if it gives you a chance for survival.

High-dose tamoxifen, a breast cancer drug, is one such medication that has shown some promise in treating glioblastoma multiforme.2

The anti-malaria drug chloroquine is another.3 There’s even a good chance your neuro-oncologist may be aware of the promising studies done with these drugs, but he or she won’t offer them as a potential treatment because they’re considered experimental. As Williams said:

“It made absolutely no sense to me not to use everything that might have a benefit as long as the toxicities were acceptable. Why wouldn’t anyone want to add them? It seemed to be totally irrational that people didn’t use everything that was available.”

When Modern Medicine Fails Them, Cancer Patients Turn to Self-Medication and the Black Market

In order to survive, Williams turned to self-medicating, a dangerous prospect by any account but, again, when your life is at stake you’re willing to take the risk. And his story is not unique.

Many have traveled to other countries, forged prescriptions, feigned illnesses to get access to different medications and even traded medications and nutraceuticals on the “black market” in order to have even a chance at survival.

In Williams’ case, his daily cocktail of off-label medications and natural products worked. In just six months, his brain tumor had disappeared and it hasn’t been back since.

There are more than a handful of others who have defied odds and lived long term with glioblastoma multiforme, and they’ve taken matters into their own hands too.

Williams now spends the bulk of his time trying to help others with terminal cancer, and he makes his book, which he updates annually, free to cancer patients in need.

Natural Cancer Fighters Overlooked by Modern Medicine

Nature is an invaluable resource for fighting cancer, yet natural products, even those that have been intensely studied, are also left out of cancer patients’ treatment plans. Curcumin — one of the most well-studied bioactive ingredients in turmeric — is one glaring example.

It exhibits over 150 potentially therapeutic activities, including anti-cancer properties.

As noted by Dr. William LaValley — a leading natural medicine cancer physician whom I’ve previously interviewed on this topic — curcumin is unique in that it appears to be universally useful for just about every type of cancer.

Superficially, this appears unusual considering the fact that cancer consists of a wide variety of different nuclear genetic defects. One reason for this universal anti-cancer proclivity is curcumin’s ability to decrease the primary mitochondrial dysfunction that is likely one of the foundational causes of cancer. Once it gets into a cell, it also affects more than 100 different molecular pathways.

And, as explained by LaValley, whether the curcumin molecule causes an increase in activity of a particular molecular target or decrease/inhibition of activity, studies repeatedly show that the end result is a potent anti-cancer activity. Moreover, curcumin is virtually non-toxic, and does not adversely affect healthy cells, suggesting it selectively targets cancer cells — all of which are clear benefits in cancer treatment.

Research has even shown that it works synergistically with certain chemotherapy drugs, enhancing the elimination of cancer cells. If you have cancer, curcumin is one substance you should be taking, but your oncologist won’t recommend it.

To Survive Cancer, Many Must Defy Their Doctors

Should you bring up the fact that you are using approaches to fight cancer that are outside of your oncologist’s realm of experience — things like supplements, medical marijuana, herbal preparations, and more — you might be scolded, berated, threatened or even fired from the practice.

Williams never told his oncologists about his self-prescribed treatment; he knew it would fall on deaf ears. The cancer industry should be learning from the people who have beaten the odds and survived terminal cancer — studying their methods and trying to apply them to others — but instead they’re ignored.

It’s an unfortunate state of affairs when patients must actively defy their doctors in order to survive. As Williams explained, going against the advice of his doctors was initially an act of desperation, but it was necessary to save his life. This certainly applies to the majority of conventional oncologists, but there are exceptions — doctors who are blazing a new trail to find a cancer cure.

This includes Dr. Marc-Eric Halatsch, a professor and senior consultant neurosurgeon at the University of Ulm, Germany, who, along with colleagues have developed a new treatment protocol for relapsed glioblastoma.

It’s based on a combination of drugs (very similar to the early HIV treatments) “not traditionally thought of as chemotherapy agents, but that have a robust history of being well-tolerated and are already marketed and used for other non-cancer indications.”4 As noted in the featured film, even though the protocol uses mainstream medications, he’s put his reputation on the line to step outside the conventional cancer-treatment box.

Cancer Patients Should Have Access to the Best of Eastern and Western Medicine

Dr. Raymond Chang, who is featured in the video above, is one such pioneer in the integration of Eastern and Western medicine. He is known for his work on anti-cancer Chinese botanicals especially involving bioactive polysaccharides and medicinal mushrooms.

He and colleagues with the Institute of East-West Medicine have created the Asian Anti-Cancer Materia Database, which brings together traditional Asian medicines that have potential anti-cancer activity into one database that can be accessed by all.5 In his book, “Beyond the Magic Bullet ― The Anti-Cancer Cocktail,” Dr. Chang explained:

“While scientists win occasional skirmishes in the battle against cancer, the overall war continues to go badly. Stories abound about revolutionary drugs that may be available in the future, but offer no real help to those who have cancer today. At present, conventional approaches continue to rely on a narrowly focused strategy of treatments, with doctors using, at best, only one or two drugs or other therapies at a time.

While this may be acceptable in a laboratory setting or a clinical trial, it has done little to diminish the number of people who die each year from this dread disease. Recently, however, conventional medicine’s core strategy has been re-examined, and a new, potentially more effective approach has emerged ― one that combines the best of Eastern wisdom with Western science.”

More Than Half a Million People Expected to Die From Cancer in 2016

In 2016, nearly 1.7 million new cases of cancer are expected to be diagnosed in the U.S., while nearly 600,000 will die from the disease.6  That is nearly 1,650 people dying EVERY DAY in the U.S. alone. Public health agencies claim that we are winning the war against cancer, but from 2003 to 2012 death rates from cancer decreased by only 1.8 percent per year among men and 1.4 percent per year among women.7

Meanwhile, the 2014 World Cancer Report issued by the World Health Organization (WHO) predicted worldwide cancer rates to rise by 57 percent in the next two decades.8

The report refers to the prediction as “an imminent human disaster,” noting countries around the world need to renew their focus on prevention rather than treatment only. Christopher Wild, Ph.D., director of the International Agency for Research on Cancer, told CNN:9

“We cannot treat our way out of the cancer problem. More commitment to prevention and early detection is desperately needed in order to complement improved treatments and address the alarming rise in cancer burden globally.”

There is so much you can do to lower your risk for cancer, but please don’t wait until you get the diagnosis — you have to take preventative steps now. Cancer doesn’t typically develop overnight, which means you have a chance to make changes that can potentially prevent cancer from developing in the first place. Most of us carry around microscopic cancer cell clusters in our bodies all the time.

The reason why we all don’t develop cancer is because as long as your body has the ability to balance angiogenesis properly, it will prevent blood vessels from forming to feed these microscopic tumors. Trouble will only arise if, and when, the cancer cells manage to get their own blood supply, at which point they can transform from harmless to deadly. It’s much easier to prevent cancer than to treat it once it takes hold.

Top Cancer Prevention Strategies

I believe you can virtually eliminate your risk of cancer and chronic disease and significantly improve your chances of recovering from cancer if you currently have it, by following these relatively simple strategies.

1.Eat REAL Food: Seek to eliminate all processed food in your diet. Eat at least one-third of your food raw. Avoid frying or charbroiling; boil, poach or steam your foods instead. Consider adding cancer-fighting whole foods, herbs, spices and supplements to your diet, such as broccoli sprouts, curcumin and resveratrol.

2.Carbohydrates and Sugar: Sugar/fructose and grain-based foods from your diet need to be reduced and eventually eliminated. This applies to whole unprocessed organic grains as well, as they tend to rapidly break down and drive up your insulin level.

The evidence is quite clear that if you want to avoid cancer, or you currently have cancer, you absolutely MUST avoid all forms of sugar, especially fructose, which are dirty fuels generating excessive free radicals and secondary mitochondrial damage.

3.Protein and Fat: Consider reducing your protein levels to 1 gram of protein for every kilogram of lean body mass, or one-half gram of protein per pound of lean body mass. Replace excess protein with high-quality fats, such as organic eggs from pastured hens, high-quality grass-fed meats, raw pastured butter, avocados, pecans, macadamias, and coconut oil.

4.GMOs: Avoid genetically engineered foods as they are typically treated with herbicides such as Roundup (glyphosate), and are likely to be carcinogenic and contribute to mitochondrial dysfunction. Choose fresh, organic, and preferably locally grown foods.

5.Animal-Based Omega-3 Fats: Normalize your ratio of omega-3 to omega-6 fats by consuming anchovies, sardines, wild Alaskan salmon or taking a high-quality krill oil and reducing your intake of processed vegetable oils.

6.Optimize Your Gut Flora: This will reduce inflammation and strengthen your immune response. Researchers have found a microbe-dependent mechanism through which some cancers mount an inflammatory response that fuels their development and growth.

They suggest that inhibiting inflammatory cytokines might slow cancer progression and improve the response to chemotherapy. Fermented foods are especially beneficial for gut health, and the fermentation process involved in creating sauerkraut produces cancer-fighting compounds such as isothiocyanates, indoles and sulforaphane.

7.Exercise and Move More: Sit less, move around more and try to take 10,000 steps a day.  Exercise also lowers insulin levels, which creates a low-sugar environment that discourages the growth and spread of cancer cells. In a three-month study, exercise was found to alter immune cells into a more potent disease-fighting form in cancer survivors who had just completed chemotherapy.

Researchers and cancer organizations increasingly recommend making regular exercise a priority in order to reduce your risk of cancer and help improve cancer outcomes. Exercise may also help trigger apoptosis (programmed cell death) in cancer cells. Ideally, your exercise program should include balance, strength, flexibility, and high-intensity interval training (HIIT). For help getting started, refer to my Peak Fitness Program.

8.Vitamin D: There is scientific evidence you can decrease your risk of cancer by more than half simply by optimizing your vitamin D levels with appropriate sun exposure. Your serum level should hold steady at 50 to 70 ng/ml, but if you are being treated for cancer, it should be closer to 80 to 90 ng/ml for optimal benefit.

If you take oral vitamin D and have cancer, it would be very prudent to monitor your vitamin D blood levels regularly, as well as supplementing with vitamin K2, as K2 deficiency is actually what produces the symptoms of vitamin D toxicity.

9.Sleep: Make sure you are getting enough restorative sleep. Poor sleep can interfere with your melatonin production, which is associated with an increased risk of insulin resistance and weight gain, both of which contribute to cancer’s virility.

10.Exposure to Toxins: Reduce your exposure to environmental toxins like pesticides, herbicides, household chemical cleaners, plastics chemicals, synthetic air fresheners and toxic cosmetics.

11.Exposure to Radiation: Limit your exposure and protect yourself from radiation produced by cell phones, towers, base stations, and Wi-Fi stations, as well as minimizing your exposure from radiation-based medical scans, including dental x-rays, CT scans, and mammograms.

12.Stress Management: Stress from all causes is a major contributor to disease. It is likely that stress and unresolved emotional issues may be more important than the physical ones, so make sure this is addressed. My favorite tool for resolving emotional challenges is the Emotional Freedom Techniques (EFT).

Have You Been Diagnosed With Cancer?

One of the most essential strategies I know of to treat cancer is to starve the cells by depriving them of their food source. Unlike your body cells, which can burn carbs or fat for fuel, cancer cells have lost that metabolic flexibility. Dr. Otto Warburg was given a Nobel Prize over 75 years ago for figuring this out, but virtually no oncologist actually uses this information.

You can review my interview with Dominic D’Agostino, Ph.D. below for more details. Integrating a ketogenic diet with hyperbaric oxygen therapy is deadly to cancer cells. It debilitates them by starving them of their fuel source. This would be the strategy I would recommend to my family members if they were diagnosed with cancer.

Watch the video discussion. URL:https://vimeo.com/119006145

Source:mercola.com

Vitamin C May Be a Potent Adjunct to Cancer Treatment



Story at-a-glance

  • Research shows vitamin C is selectively cytotoxic to cancer cells when administered intravenously in high doses, and has a number of heart and cardiovascular benefits
  • When given intravenously at high doses, vitamin C produces a pro-oxidant effect, thereby generating hydrogen peroxide, which is ultimately what kills the cancer cells
  • Normal tissues are not harmed by the high levels of hydrogen peroxide generated because healthy cells have several ways of effectively removing it, thereby preventing buildup to toxic levels. Cancer cells lack this ability

Vitamin C is one of the most well-established traditional antioxidants known and its potent health benefits have been clearly demonstrated over time — especially for the prevention and treatment of infectious diseases.

Research has also shown that vitamin C is selectively cytotoxic to cancer cells when administered intravenously (IV) in high doses, and has a number of heart- and cardiovascular benefits.

From my perspective, vitamin C is a very useful supplement that should be part of most cancer treatment protocols. Vitamin D is another crucial anti-cancer component I’ve written about on numerous occasions.

How Vitamin C Kills Cancer Cells

In order for vitamin C to effectively kill cancer cells, you need to have a very high concentration of vitamin C in your blood, and the only way to obtain these extreme levels is through IV administration, although using oral liposomal vitamin C can approach effectiveness at a fraction of the price, improved convenience and cost.

By bypassing the digestive tract, IV administration results in blood levels up to 500 times higher than what you can achieve through the oral route.

The mechanism behind vitamin C’s ability to selectively target cancer cells has to do with the generation of hydrogen peroxide, which is ultimately what kills the cancer cells. As reported by the University of Iowa:1

“In a new study2,3 … Buettner and his colleagues have homed in on the biological details of how high-dose vitamin C kills cancer cells. The study shows that vitamin C breaks down easily, generating hydrogen peroxide, a so-called reactive oxygen species that can damage tissue and DNA.

The study also shows that tumor cells are much less capable of removing the damaging hydrogen peroxide than normal cells …

‘Thus, cancer cells are much more prone to damage and death from a high amount of hydrogen peroxide,’ says Buettner, a professor of radiation oncology and a member of Holden Comprehensive Cancer Center at the University of Iowa.

‘This explains how the very, very high levels of vitamin C used in our clinical trials do not affect normal tissue, but can be damaging to tumor tissue.’”

The reason normal tissues are not harmed by the high levels of hydrogen peroxide generated is that healthy cells have several ways of effectively removing it, thereby preventing buildup to toxic levels.

One of the primary pathways of removal is the enzyme catalase, and the study found that cells with reduced catalase activity were indeed more prone to die when exposed to high amounts of vitamin C.

This provides a hint at which cancers are likely the best candidates for high-dose vitamin C therapy — tumors with low catalase levels are likely to be the most responsive, whereas tumors with high catalase levels would be the least responsive. Next, the research team wants to develop methods to measure catalase in tumors.

Vitamin C Lowers Inflammation in Cancer Patients, and More

Another way vitamin C benefits cancer is by lowering inflammation in your body, as shown in a 2012 study.4,5,6

As a general rule, chronic inflammation is a hallmark of cancer, and here they found that IV vitamin C treatment helps lower pro-inflammatory cytokines and C-reactive protein — two inflammatory markers — and that these improvements correlate with a reduction in tumor size.

It also helps lower the risk of metastasis. A positive response was noted in 75 percent of patients. This study was done by scientist at the Riordan Clinic, which is the successor to Linus Pauling and his work on vitamin C. There is likely no clinic in the world with as much experience with vitamin C as the Riordan Clinic.

Riordan carried out a 15-year-long research project called RECNAC (cancer spelled backwards), which showed vitamin C was selectively cytotoxic against cancer cells.

Other research7,8 done by scientists at the Lewis Cantley of Weill Cornel Medicine in New York found high doses of vitamin C helps kill and eliminate colorectal cancer cells with certain genetic mutations. Other studies9 have shown high-dose vitamin C can help slow the growth of prostate-, pancreatic-, liver- and colon cancer cells.

Human studies also show IV vitamin C can help improve symptoms associated with cancer and cancer treatment, such as fatigue, nausea, vomiting, pain and loss of appetite, and improve overall quality of life.

Vitamin C for Infectious Diseases

Vitamin C may be best known for its ability to combat infectious disease. Dr. Thomas Levy’s book, “Curing the Incurable,” details these benefits.

A perfect real-world example is the dramatic case of Allan Smith, who contracted a serious case of swine flu and was brought back from the brink of death using a combination of IV and oral vitamin C.

The case report was sent to me by Levy, who noted that, to his knowledge, vitamin C “has never failed to cure an acute viral syndrome.” According to Albert Szent-Gyorgyi (who won the Nobel Prize in 1937 for his discovery of vitamin C), “health” occurs when there is an ample flow and interchange of electrons in your cells.

Impaired or poor electron flow and interchange equals “disease,” and when the flow and interchange ceases entirely, your cells die. Oxidation, caused by free radicals in your body, involves the loss of electrons.

Antioxidants, both from your diet and endogenously produced, counter the disease process caused by oxidation (loss of electrons) by supplying electrons. Vitamin C is a major antioxidant, and according to Levy, perhaps the most important electron donor to maintain optimal electron flow in your cells.

In 2005, the Orthomolecular Medicine News Service (a non-profit and non-commercial informational resource), published findings that vitamin C is an effective treatment against the dreaded bird flu and other viruses.10

As with cancer, extremely high doses are needed though — upwards of 200,000 to 300,000 milligrams (mg) of vitamin C, given intravenously. The reason for this is because the avian flu appears to “consume vitamin C very rapidly, similar to an acute viral hemorrhagic fever, somewhat like an Ebola infection.”

A number of other studies and clinical experiences also attest to vitamin C as a potent treatment strategy against all sorts of infectious diseases, including influenza,11 encephalitis and measles.12

Vitamin C for Sepsis

Vitamin C in combination with thiamine (B1) and hydrocortisone has also been shown to be dramatically helpful in the treatment of severe sepsis and septic shock. Sepsis is a life-threatening condition triggered by a systemic infection, caused by bacteria, viruses or parasites that ultimately affects the function of vital organs. Hospital-acquired infections that progress to sepsis is a significant cause of death.

As many as half of all in-hospital deaths are related to sepsis,13 and recent research published in the Canadian Medical Association Journal proposes sepsis should be recognized as a distinct cause of death in hospitals around the world.14 The cost of treating sepsis is high, topping $24 billion in 2014, with nearly 25 percent of all hospital charges attributed to the treatment of sepsis. As reported by Dr. Malcolm Kendrick, the study in question:15

“… demonstrates that if you give vitamin C (along with hydrocortisone and thiamine) for just over two days in patients admitted with sepsis (blood poisoning) the mortality rate falls from 40 percent to 8.5 percent. The mortality rate in low income countries is normally around 60 percent. Now, this was a small study, but it seems robust. It represents an almost five-fold reduction in mortality … ”

Vitamin C Is Also Good for Your Heart, Blood Vessels, Lungs and Eyes

Other studies focused on vitamin C shows it helps:

  • Decrease risk of post-operative atrial fibrillation after heart surgery, thereby reducing the risk of stroke and heart failure. It also reduced the length of hospitalization after heart surgery. Oral administration reduced the length of hospital stay by 7 percent (less than half a day), whereas IV shortened it by 16 percent (1.5 days)16,17
  • Reduce high blood pressure — likely by protecting your body’s supply of nitric oxide (NO), a molecule that relaxes blood vessels. In one study,18 both the systolic and diastolic (top and bottom) readings were inversely associated with ascorbic acid levels. Specifically, women with the highest levels of ascorbic acid had about 4.6 mm Hg lower systolic and just over 6 mm Hg lower diastolic blood pressure compared to those with the lowest ascorbic acid levels
  • Reduce your risk of chronic obstructive pulmonary disease (COPD), especially among smokers. In one study, heavy smokers with the highest vitamin C intake had a 77 percent lower risk of COPD than those with the lowest intake.19 The mechanism for this effect is thought to be related to vitamin C’s ability to improve levels of vascular endothelial growth factor, and boost proliferation of alveolar cells in your lungs
  • Prevent heart attacks, primarily by reducing inflammation20
  • Protect your vision by improving the function of your retinal cells, and reduce your risk for cataracts by fighting oxidative stress

Important Contraindication for IV Vitamin C Treatment

While the evidence strongly supports the use of IV vitamin C in high doses for infections, inflammation and even cancer, it’s important to get your glucose-6-phosphate dehydrogenase (G6PD) checked beforehand. G6PD is an enzyme your red blood cells need to maintain membrane integrity. High-dose IV vitamin C is actually a strong PRO-oxidant, and giving a pro-oxidant to a G6PD-deficient individual can cause hemolysis (rupturing) of their red blood cells.

So, administering IV vitamin C is not for the novice! I strongly recommend getting it done by an experienced practitioner who uses the Riordan protocol or some other protocol that ensures its done in a safe manner. Fortunately, G6PC deficiency is relatively uncommon.

People of Mediterranean- and African decent are at greater risk, but it’s rare even in those groups. Still, while it’s not a great concern that will prevent its use in most people, should you happen to be that rare person with a G6PC deficiency, the ramifications of barreling ahead with high dose IV vitamin C could be disastrous.

General Vitamin C Dosage Suggestions

Dr. Ronald Hunninghake — chief medical officer at the Riordan Clinic who has supervised 60,000 IV administrations of vitamin C — discusses the use of vitamin C for health and cancer protocols in the featured video. For cancer, research by the Riordan Clinic suggests you need a vitamin C blood level of around 300 to 400 mg/dl to achieve selective cytotoxicity against cancer cells.

To reach that post-IV saturation level, you’d need to administer somewhere between 25 to 50 grams of vitamin C intravenously. That’s up to 300 times the normal amount of vitamin C you’d get from eating a healthy diet. It’s important to understand that these extremely high levels are really only indicated for the treatment of cancers and infectious diseases, not for everyday, general health.

This is because vitamin C starts to have a pro-oxidant effect at these extreme levels — this is in fact what causes the hydrogen peroxide to be created in the first place. In other words, the hydrogen peroxide is a pro-oxidant effect of the vitamin C, so it needs to be used judiciously. You can learn more about using vitamin C as an adjunct to your cancer protocol on the Riordan Clinic’s website.21

For everyday health, I believe your best bet is to eat a varied whole food diet, rich in vitamin C and other antioxidants, to avoid causing a nutritional imbalance.

For example, taking large doses of vitamin C (ascorbic acid) on a regular basis lowers your copper level, so if you are already deficient in copper and take high doses of vitamin C, you can compromise your immune system. So, while temporarily taking mega-doses of vitamin C supplements to combat a case of the cold or flu is unlikely to cause a problem, for long-term, daily use, you’re probably going to be better off simply squeezing some lemon juice into a glass of water and/or eating a vitamin C-rich diet.

Also remember that vitamin C is a water-soluble vitamin, so when you do take a supplement, it’s best to divide your daily dose and take it three times a day. Also, if you’re sensitive to vitamin C, you may experience diarrhea. This is an indication that you need to lower your dosage.

Lastly, evidence suggests liposomal vitamin C provides better absorption, so it’s my personal favorite. I always bring some liposomal vitamin C with me when I travel in case I or someone I travel with gets sick, and then I use two to four capsules every hour until better.

Watch the video discussion. URL:https://youtu.be/vX1jtV9wU-g

Breakthrough new cancer treatment destroys 95% of cancer cells in tumors in mice in 2 hours.


A highly effective cancer treatment has been developed by Matthew Gdovin, an associate professor in the UTSA Department of Biology.  The treatment involves the injection of a chemical compound, nitrobenzaldehyde, into tumor cells and inducing their death.

“Even though there are many different types of cancers, the one thing they have in common is their susceptibility to this induced cell suicide,” said Gdovin.  “All forms of cancer attempt to make cells acidic on the outside as a way to attract the attention of a blood vessel,” he said.  Once the cancer cells attach to a blood vessel, they use it to grow the tumor.

This treatment sees the nitrobenzaldehyde injected into cancerous cells.  From there, ultraviolet light is shined onto the cells, causing them to become more acidic.  Eventually, they become so acidic that they destroy themselves.  The cancer is decimated, while the healthy cells are left untouched.

When treated, 95% of the cancer cells are destroyed, mice have tumor growth halted and their chance of survival was doubled.

Gdovin also shows that this treatment can help destroy cancer in hard-to-reach areas, like the brain stem.

 

“There are so many types of cancer for which the prognosis is very poor,” he said. “We’re thinking outside the box and finding a way to do what for many people is simply impossible.”

Nutritional Needs during Cancer Treatment


Although a given diet can­not prevent or cure can­cer, good nutrition can reduce disease risk as well as improve quality of life, immune function, healing, and even survival. That’s good news.

Practically speaking, this begs the questions: What is good nutrition? What should I eat, and what should I consume for the best benefit?

I’m not going to present a list of good or bad foods or do’s and don’ts because the best diet for anyone, but particularly in the context of cancer, is different from one person to the next—there’s no cookie-cutter answer. It is important to think about what your nutrition goals are, both in the present and over the long term, and consider big-picture best practices.

General Guidelines for Good Nutrition

Keeping in mind the importance of individual variability and needs, for most people an ideal diet has some common characteristics: it is mostly plant based, with the right amount of calories to maintain a healthy weight and lean body mass, and it includes a variety of whole vegetables and fruits and minimal added sugars. The American Cancer Society suggests limiting alcohol intake and mini­mizing red and processed meats. An ideal diet is sustainable, flexible, and long term—it’s a lifestyle. Following a balanced diet is not the same things as “going on a diet.”

Of course, there are always excep­tions. Cancer symptoms and treatment side effects may mean you have to adjust your diet. Here are some examples:

  • If you are experiencing acute di­arrhea, you would want to reduce fiber-rich vegetables and whole grains and instead choose white rice and plain toast.
  • If you have changes in taste that make it hard to drink plain water, which is important to stay hy­drated, try flavored seltzer or add cucumber or lemon to your water.
  • If you feel nauseated, it might be best to avoid hot foods or foods with strong odors and instead try cool, bland foods, as well as ginger tea.
  • Always ask to speak with a reg­istered dietitian or nutritionist if you have specific concerns.

Remember, do your best at any given point to eat healthfully without mak­ing yourself miserable or worrying that your food choices are hurting you. If you have had no appetite for days and have lost weight and then one day you crave chocolate-chip cookies, let yourself have them—and enjoy them.

Weight Gain or Loss Associated with Treatment

Unplanned weight loss and weight gain may occur during and after cancer treatment. These changes can

be related to the disease itself, behav­ioral changes, medications, and other factors. Some types of cancer are more associated with weight gain, others with weight loss. For example, about half of women who receive adjuvant treatment for breast cancer gain weight; women and men treated for head and neck cancer lose weight.

Either gaining or losing too much weight can be a problem. In the setting of breast cancer, for example, undesired weight gain may increase recurrence risk, other disease risk, and risk of death. On the flip side, excess unintentional weight loss and underweight are associated with poorer outcomes. Excess or insuffi­cient body weight can also compro­mise healing, immune function, and quality of life, including one’s mood, social well-being, and energy level.

If you gain excess weight during treatment, be assured that while losing weight is never easy, it is still possible. One of the best places to start is keeping a written food diary: this immediately increases your accountability and makes you more aware of your food choices. Portion control is also very important. I find that many people are not eating foods that are unhealthy—they’re just eating too much. Go slowly and eat mindfully. Your brain needs at least 20 minutes to recognize that your stomach is full. If you rush through a meal you’ll often end up overeating. Learn to read your body’s natural appetite and satiety cues; if you tend to eat when you’re not physically hungry—and we all do that sometimes—check in with what you really need and want. If you are very tired or stressed, for example, you would probably feel better by sitting down with a favorite book or calling a friend or going for a walk. Always have something you’re looking forward to beyond your next meal or snack.

On the other hand, if you have lost weight without wanting to, be patient with yourself. Sometimes it’s best to set an immediate goal of maintaining your current weight rather than putting pressure on your­self to regain. Increase your intake gradually, eating frequently in small amounts that don’t feel overwhelm­ing. Homemade shakes and smooth­ies can add calories without making you feel overfull. You might want to try a smoothie, for example, made with almond milk, cocoa, a banana, and honey. Commercial supplement drinks are also available. Try to choose foods that will give you some pleasure, and incorporate foods that are high in calories (don’t be afraid to have full-fat rather than low-fat versions of food).

Keep Calm and Carry On

Making good choices about nutrition can be an empowering step you can take during and after cancer treat­ment. If you need guidance about what the best choices are, given your unique needs, diagnosis, and treat­ment, speak with your care team.

Nutritional Needs during Cancer Treatment


Although a given diet can­not prevent or cure can­cer, good nutrition can reduce disease risk as well as improve quality of life, immune function, healing, and even survival. That’s good news.

Practically speaking, this begs the questions: What is good nutrition? What should I eat, and what should I consume for the best benefit?

I’m not going to present a list of good or bad foods or do’s and don’ts because the best diet for anyone, but particularly in the context of cancer, is different from one person to the next—there’s no cookie-cutter answer. It is important to think about what your nutrition goals are, both in the present and over the long term, and consider big-picture best practices.

General Guidelines for Good Nutrition

Keeping in mind the importance of individual variability and needs, for most people an ideal diet has some common characteristics: it is mostly plant based, with the right amount of calories to maintain a healthy weight and lean body mass, and it includes a variety of whole vegetables and fruits and minimal added sugars. The American Cancer Society suggests limiting alcohol intake and mini­mizing red and processed meats. An ideal diet is sustainable, flexible, and long term—it’s a lifestyle. Following a balanced diet is not the same things as “going on a diet.”

Of course, there are always excep­tions. Cancer symptoms and treatment side effects may mean you have to adjust your diet. Here are some examples:

  • If you are experiencing acute di­arrhea, you would want to reduce fiber-rich vegetables and whole grains and instead choose white rice and plain toast.
  • If you have changes in taste that make it hard to drink plain water, which is important to stay hy­drated, try flavored seltzer or add cucumber or lemon to your water.
  • If you feel nauseated, it might be best to avoid hot foods or foods with strong odors and instead try cool, bland foods, as well as ginger tea.
  • Always ask to speak with a reg­istered dietitian or nutritionist if you have specific concerns.

Remember, do your best at any given point to eat healthfully without mak­ing yourself miserable or worrying that your food choices are hurting you. If you have had no appetite for days and have lost weight and then one day you crave chocolate-chip cookies, let yourself have them—and enjoy them.

Weight Gain or Loss Associated with Treatment

Unplanned weight loss and weight gain may occur during and after cancer treatment. These changes can

be related to the disease itself, behav­ioral changes, medications, and other factors. Some types of cancer are more associated with weight gain, others with weight loss. For example, about half of women who receive adjuvant treatment for breast cancer gain weight; women and men treated for head and neck cancer lose weight.

Either gaining or losing too much weight can be a problem. In the setting of breast cancer, for example, undesired weight gain may increase recurrence risk, other disease risk, and risk of death. On the flip side, excess unintentional weight loss and underweight are associated with poorer outcomes. Excess or insuffi­cient body weight can also compro­mise healing, immune function, and quality of life, including one’s mood, social well-being, and energy level.

If you gain excess weight during treatment, be assured that while losing weight is never easy, it is still possible. One of the best places to start is keeping a written food diary: this immediately increases your accountability and makes you more aware of your food choices. Portion control is also very important. I find that many people are not eating foods that are unhealthy—they’re just eating too much. Go slowly and eat mindfully. Your brain needs at least 20 minutes to recognize that your stomach is full. If you rush through a meal you’ll often end up overeating. Learn to read your body’s natural appetite and satiety cues; if you tend to eat when you’re not physically hungry—and we all do that sometimes—check in with what you really need and want. If you are very tired or stressed, for example, you would probably feel better by sitting down with a favorite book or calling a friend or going for a walk. Always have something you’re looking forward to beyond your next meal or snack.

On the other hand, if you have lost weight without wanting to, be patient with yourself. Sometimes it’s best to set an immediate goal of maintaining your current weight rather than putting pressure on your­self to regain. Increase your intake gradually, eating frequently in small amounts that don’t feel overwhelm­ing. Homemade shakes and smooth­ies can add calories without making you feel overfull. You might want to try a smoothie, for example, made with almond milk, cocoa, a banana, and honey. Commercial supplement drinks are also available. Try to choose foods that will give you some pleasure, and incorporate foods that are high in calories (don’t be afraid to have full-fat rather than low-fat versions of food).

Keep Calm and Carry On

Making good choices about nutrition can be an empowering step you can take during and after cancer treat­ment. If you need guidance about what the best choices are, given your unique needs, diagnosis, and treat­ment, speak with your care team.