Compounds in herbal supplement kratom are opioids, FDA says


On Tuesday, USDA Commissioner Scott Gottlieb warned the public about the dangers of the herbal supplement kratom saying “There is no evidence to indicate that kratom is safe or effective for any medical use.”1
The leaves of the kratom plant, which is native to Malaysia, are traditionally crushed and then made into a tea to treat pain or heroin/morphine dependence (by reducing withdrawal cravings). And according to its 3 to 5 million U.S. users, it’s a game changer and a life saver.

PUBLIC COMMENTS AND SCIENTIFIC REVIEW

However, the DEA and FDA aren’t so sure. Thankfully, since requesting public comment about Kratom and calling for a scientific review by the FDA, the agency hasn’t taken any further steps to make its use illegal. But the plant is still listed as a “drug of concern”. (You’ve got to wonder if they are doing that because it hurts their bottom line.)

“To better understand the plant, the FDA conducted computer modeling that predicted that many of the chemical compounds found in kratom bind to the same receptors as narcotic drugs such as oxycodone and hydrocodone.

But researchers who study the plant, including Scott Hemby, say the agency is making too broad of a statement. Hemby chairs the Department of Basic Pharmaceutical Sciences at High Point University in North Carolina and has been researching the abuse liability or ‘addictiveness’ of kratom.”2

While the model indicates that kratom compounds might affect the body just like opioids, which Hemby has seen in his research, he says that they do not bind to opioid receptors the same way the chemicals in heroin or oxycodone do, “Just because it binds, it doesn’t mean it has the same efficacy.”3 Instead, the compounds in kratom “sit on different parts of the receptor and fit differently than the chemicals in heroin and oxycodone.”4 And that means kratom use doesn’t lead to overdose fatalities the way opioids do. (But you know Scott Gottlieb, science is hard.)

IS IT REALLY THAT DANGEROUS?

In 2010 the CDC reported just 26 calls to poison control centers about kratom, it 2015 that number had gone up to 263. But the FDA is now blaming the plant for 44 deaths, another issue Hemby takes with the agency- because there was no proof from toxicology or autopsy reports. And he’s not alone, Christopher McCurdy, a medicinal chemist at the University of Florida, has analyzed samples of kratom from emergency room patients and found that very often they aren’t even what they claim to be.5
If the FDA continues to paint with such a broad brush, it could potentially put serious regulations on kratom’s study and use and that could be devastating to many people.
We’ve been watching this story since 2016 and will continue to do so. If the FDA really just wants to protect people they need to make the drug available for proper “intact animal models and humans”6 rather than simply write it off.
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Pharma Co has license suspended as vaccine blamed for sterilization of 500,000 women & children


A state-sponsored forced sterilization on a massive scale has allegedly taken place in Africa according to opposition leaders and the public who are railing against the government. An industrial pharmaceutical laboratory has since had its license suspended by the Kenya Accreditation Service as a result of the controversy.

Kenya’s opposition leader Raila Odinga—who swore himself in as president on Tuesday—claimed that at least 500,000 young girls and women may be infertile, following a tetanus vaccine administered by the government in 2014 and 2015.

The controversy began coming to a head in 2016 when Agriq-Quest Ltd, a Nairobi-based pharmaceutical company got in a dispute with Kenya’s Ministry of Health over their tetanus and polio vaccinations. A group of Catholic doctors originally made the accusations claiming that the vaccines may contain a hormone that is dangerous to young women and can cause potential sterilization.

As the Agence de Presse Africaine reported:

Odinga said girls and women aged between 14 and 49 from the fastest growing populations in the country will not have children, because of a state-sponsored sterilization exercise that was sold to the country as a tetanus vaccination.

The Catholic Church was ignored when it mounted a strong but lonely campaign against the mass tetanus vaccination, after it raised concerns about the safety of the vaccine that was being used, he said.

At the time, the Catholic Church in Kenya claimed that the tetanus vaccine used by the government of Kenya and UN agencies was contaminated with a hormone (hCG) that can cause miscarriages and render some women sterile.

“The Church’s position was informed by what had happened in Mexico, Nicaragua and Philippines, where the various governments together with WHO/UNICEF had conducted similar campaigns using tetanus toxoid impregnated with beta human chorionic gonadotropin (BhCG) that causes permanent infertility among girls and women,” Odinga continued.

Odinga says they confirmed through analysis of samples that the vaccines used were tainted with the hormone.

“Today, we can confirm to the country that the Catholic Church was right. Hundreds of thousands of our girls and women, aged between 14 and 49, from the fastest growing populations in the country will not have children, because of the state-sponsored sterilization that was sold to the country as tetanus vaccination,” he declared.

After Agriq-Quest’s license was suspended, the company pointed the finger at the government. They claimed that the government’s decision to suspend their license was due to the fact that Agriq-Quest refused to doctor the tests for them.

According to Business Dailly Africa, when Agriq-Quest conducted the tests on the vaccines, they found the Catholic Church’s suspicions to be correct.

As BDA reported, “The company’s results from tests carried out on the vials showed that the samples of the vaccines were contaminated as had been claimed by the Catholic Church and Agriq-Quest claimed the government wanted the results altered to show that they were fit to be administered to women and children.”

According to Odinga, as reported by APA, the government, for some mysterious reason, was hell-bent on misleading the country, while intentionally sterilizing Kenyan girls and women.

“The vaccines were a great crime committed against women. Women should choose when to have children and how to space them,” he said.

It is important to point out that the belief that tetanus vaccinations sterilizing citizens has been a long time controversy in Kenya and has been disproven prior to these claims.

RELATED STORY:

Holistic MD who sounded the alarm on vaccine damage was targeted for murder when the brake lines of her vehicle were secretly clamped

Also, after the discussion came to a head, in spite of claims of tests showing contamination, UNICEF and the World Health Organization later said that the vaccines were safe and procured from a pre-qualified manufacturer.

However, according to Odinga, they accessed the analysis from four highly-regarded institutions, such as Agriq Quest Ltd, the Nairobi Hospital Laboratories, the University of Nairobi and Lancet Kenya.

“These results all indicate that the Tetanus Toxoid Vaccine had high contents of beta human chorionic gonadotropin hormone (BhCG) that causes sterility in women.”

Aluminum, Fluoride and Glyphosate — A Toxic Trifecta Implicated in Autism and Alzheimer’s Disease Research


Aluminum is a known neurotoxin, and according to Professor Christopher Exley of Keele University, aluminum-containing products are likely fueling the rise in Alzheimer’s disease. In an article published in the journal Frontiers in Neurology, he writes: “We are all accumulating a known neurotoxin in our brain from our conception to our death. The presence of aluminium in the human brain should be a red flag alerting us all to the potential dangers of the aluminium age. How do we know that Alzheimer’s disease is not the manifestation of chronic aluminium toxicity in humans?”

People with aluminum toxicity display many of the same symptoms as those with dementia, Parkinson’s, ADHD, autism, and other neurological diseases, and mounting evidence suggests aluminum may play a significant role in the development of those (and other) diseases.

By taking steps to protect yourself, you can minimize your exposure while maximizing your body’s ability to rid itself of this toxic metal, which will move you toward a long and healthy life well into your senior years. Other toxins to beware of also include fluoride and glyphosate; all of these are toxic in their own right, but research suggests they may be even more hazardous in combination.

You May Be Exposed to More Aluminum Than You Think

Aluminum can be found in a wide range of consumer products, including:

  • Foods such as baking powder, self-rising flour, salt, baby formula, coffee creamers, baked goods, and processed foods, coloring, and caking agents.
  • Drugs, such as antacids, analgesics, anti-diarrheals, and others; additives such as magnesium stearate.
  • Vaccines, including Hepatitis A and B, Hib, DTaP (diphtheria, tetanus, pertussis), pneumococcal vaccine, Gardasil (HPV), and others — many of which also contain also contain glyphosate.
  • Cosmetics and personal care products such as antiperspirants, deodorants (including salt crystals, made of alum), lotions, sunscreens, and shampoos.
  • Aluminum products, including foil, cans, juice pouches, tins, and water bottles.

According to the CDC, the average adult in the US consumes about seven to nine mg of aluminum per day in food, plus a lesser amount from air and water.

Approximately one percent of the aluminum you ingest orally gets absorbed into your body, the rest is moved out by your digestive tract — providing it’s functioning at its optimum. The remaining aluminum is then deposited not only in brain tissue, but also in your nerves, bone, liver, heart, spleen, and muscle.

While one percent may sound like a tiny amount, your overall toxic load will depend on the total amount of toxins you’re exposed to over time. Your diet and digestive health, as well as ongoing toxic exposures, will also determine how much your body is actually able to eliminate and how much builds up in the body.

Occupational Exposure to Aluminum Raises Your Risk for Alzheimer’s

One published case study found high levels of aluminum in the brain of a man who was exposed to aluminum at work for eight years. He later died from Alzheimer’s disease. According to the authors, it’s the first case showing a direct link between Alzheimer’s disease and elevated brain aluminum following occupational exposure.

Another study suggested that aluminum from food and drinking water may be contributing to rising Alzheimer’s rates, noting that:

“In recent years, interest in the potential role of metals in the pathogenesis of Alzheimer’s disease (AD) has grown considerably. In particular, aluminum (Al) neurotoxicity was suggested after its discovery in the senile plaques and neurofibrillary tangles that represent the principal neuropathological hallmarks of AD.

“Al is omnipresent in everyday life and can enter the human body from several sources, most notably from drinking water and food consumption… [O]ther elements present in drinking water, such as fluoride, copper, zinc, or iron could also have an effect on cognitive impairment or modify any Al neurotoxicity.”

Indeed, dozens of studies have shown that fluoride causes brain damage and lowers IQ. Fluoride emitted by aluminum plants has also been implicated in animal disease. Farmers in Iceland, for example, claim their animals are being sickened by environmental fluoride contamination — some to the point of having to be euthanized. Others report higher rates of tooth damage and infertility among their livestock. (You can learn more about the damaging effects of fluoride exposure here.)

Another related study linked occupational exposure to aluminum to the development of pulmonary fibrosis, a condition in which scarring on your lungs make it difficult to breathe. In this case, the exposure occurred during sanding of Corian material.

All in all, it seems reasonable to conclude that the combination of aluminum, fluoride, and/or a number of other toxins, can promote Alzheimer’s disease in addition to a number of other health problems. (You can learn more here.)

Pesticides Can Also Wreak Havoc with Brain Function

Pesticides, for example, have also been shown to have an adverse effect on neurological function and brain health In one study, farmers exposed to organochlorine insecticides had a 90 percent increased risk of depression compared to those who didn’t use them. Exposure to fumigants increased the risk of depression by 80 percent. People exposed to pesticides are also more likely to have Parkinson’s disease.

Glyphosate is also known to damage the liver and kidneys, significantly increase the risk of cancer, and enhance the damaging effects of other chemical residues and toxins.

Of course, when it comes to toxins in general, unless the chemical is acutely toxic, the real harm occurs when your body becomes chronically overloaded with them, and most people today are exposed to thousands and perhaps tens of thousands of different chemicals on a regular basis. And farmers are not the only ones at risk for adverse effects from pesticide exposure: Glyphosate can be found in most processed foods in the Western diet courtesy of GE sugar beets, corn, and soy — and is even found in tampons, vaccines, it is literally everywhere.

While nearly one billion pounds of glyphosate is doused on both conventional and genetically engineered (GE) crops worldwide each year, GE crops receive the heaviest amounts. Meats from animals raised in confined animal feeding operations (CAFOs) may also contain higher amounts of glyphosate residues, as GE soy is a staple of conventional livestock feed.

Unfortunately, glyphosate doesn’t just stay within the boundary of conventional and GMO crops; it spreads — as documented in this report — contaminating everything, including organics, completely disrupting the natural balance of soil biology.

It’s also crucial to understand that glyphosate contamination is systemic, meaning it is integrated into every cell of the plant, from root to tip. Normally, you need to thoroughly wash your produce to remove topical pesticide residues, but you simply cannot remove glyphosate from your produce. This is part and parcel of what makes GE foods so harmful to your health — it’s not just an issue of topical contamination, as with many other agricultural chemicals sprayed on crops.

Synergistic Poisoning from Aluminum and Glyphosate Implicated in Autism Research

Dr. Stephanie Seneff, a senior research scientist at Massachusetts Institute of Technology (MIT), has been instrumental in educating people about the hazards of glyphosate. In the video below, she explains how aluminum and glyphosate act together as synergistic poisons that promote autism. Based on the current trend, Dr. Seneff predicts that by 2025, half of all children born will be diagnosed with autism. Clearly, we must identify leading environmental factors contributing to this frightening trend. Lack of vitamin D caused by inadequate sun exposure is one factor. Nutritional deficiencies caused by poor diet are another.

Environmental toxins must not be overlooked however, and some toxins—glyphosate and aluminum included—are far more hazardous and ubiquitous than others, and are therefore likely to contribute to a greater degree. As Dr. Seneff explains, glyphosate’s mechanism of harm renders it particularly problematic. Indeed, according to Dr. Seneff, glyphosate is possibly “the most important factor in the development of multiple chronic diseases and conditions that have become prevalent in Westernized societies”, including but not limited to:

Autism Gastrointestinal diseases such as inflammatory bowel disease, chronic diarrhea, colitis, and Crohn’s disease Obesity
Allergies Cardiovascular disease Depression
Cancer Infertility Alzheimer’s disease
Parkinson’s disease Multiple sclerosis ALS and more

Tips for Avoiding These Pernicious Toxins

It seems quite clear that aluminum exposure plays a role in neurodegenerative diseases like Alzheimer’s. Other neurotoxins such as fluoride and glyphosate add to the toxic burden. The best way to protect yourself is to be careful about your choices in food and personal products, and minimize your use of vaccines and other drugs that are often contaminated with aluminum. Optimizing your dietary sulfur is also essential, as your body needs sulfur to manufacture its number one weapon against aluminum overload: glutathione.

By taking a few steps to protect yourself, you’ll minimize your exposure while maximizing your body’s ability to rid itself of this toxic metal, which will move you toward a long and healthy life well into your senior years. For additional tips and strategies that can help prevent and/or treat Alzheimer’s, please see my previous article “Two Exciting Alzheimer’s Advances: A Novel Early Detection Test Using Peanut Butter, and a Study Evaluating Coconut Oil.

The following list offers a number of suggestions for items to avoid, to reduce your exposure to aluminum, fluoride, glyphosate, and other brain-harming components:

Processed foods and sodas. This will help you avoid both GE ingredients (which tend to be contaminated with glyphosate) and aluminum. In addition, replacing processed foods with whole organic foods will drastically reduce your sugar/fructose intake, which will help normalize your insulin and leptin sensitivity. This is in fact one of the best strategies for protecting and preserving your brain function and overall health. Fructose and gluten are other dietary factors that promote Alzheimer’s, and are best avoided as much as possible.
Mechanically de-boned chicken, which tends to be high in fluoride as a result of the processing.
Dental amalgams. Dental amalgam fillings, which are 50 percent mercury by weight, are one of the major sources of heavy metal toxicity. However, you should be healthy prior to having them removed. Once you have adjusted to following the diet described in my optimized nutrition plan, you can follow the mercury detox protocol and then find a biological dentist to have your amalgams removed.
Cosmetics and personal care products containing aluminum, such as antiperspirants (including salt crystals, made of alum), lotions, sunscreens, and shampoos.
Vaccines containing either mercury (thimerosal) and/or aluminum.
Aluminum-containing drugs, such as antacids, analgesics, anti-diarrheals, and others
Anticholinergics and statin drugs. Drugs that block acetylcholine, a nervous system neurotransmitter, have been shown to increase your risk of dementia. These drugs include certain nighttime pain relievers, antihistamines, sleep aids, certain antidepressants, medications to control incontinence, and certain narcotic pain relievers.Statin drugs are particularly problematic because they suppress the synthesis of cholesterol, deplete your brain of coenzyme Q10 and neurotransmitter precursors, and prevent adequate delivery of essential fatty acids and fat-soluble antioxidants to your brain by inhibiting the production of the indispensable carrier biomolecule known as low-density lipoprotein.
Fluorinated medications, including Cipro.
Fluoridated water
Fluoridated toothpaste and fluoride gel treatments.
Non-stick cookware will outgas fluoride, but also avoid other aluminum-containing products, such as cans, foil, juice pouches, tins, and water bottles.

Methyldopa found effective for preventing onset of type 1 diabetes


https://speciality.medicaldialogues.in/methyldopa-found-effective-for-preventing-onset-of-type-1-diabetes/

Digital scanning technology that could halve the number of liver biopsies


https://speciality.medicaldialogues.in/digital-scanning-technology-that-could-halve-the-number-of-liver-biopsies/

Novel bedside imaging technology for faster detection of deep lung infections


https://speciality.medicaldialogues.in/novel-bedside-imaging-technology-for-faster-detection-of-deep-lung-infections/

Rosuvastatin most peferred statin for hyperlipidaemia


https://speciality.medicaldialogues.in/rosuvastatin-most-peferred-statin-for-hyperlipidaemia/

Hand hygiene protocols lower antibiotic requirement and mortality


https://speciality.medicaldialogues.in/hand-hygiene-protocols-lower-antibiotic-requirement-and-mortality/

Cranial Electrical Stimulation helpful in Depression & Anxiety


https://speciality.medicaldialogues.in/cranial-electrical-stimulation-helpful-in-depression-anxiety/

Higher intakes of yogurt associated with reduction in risk of MI


https://speciality.medicaldialogues.in/higher-intakes-of-yogurt-associated-with-reduction-in-risk-of-mi/