Onions — A Powerful Anti-Cancer Food Staple


Story at-a-glance

  • People with the highest consumption of onions have a lower risk of several types of cancer, including ovarian, endometrial, liver, colon, kidney, esophageal, laryngeal, prostate, colorectal and breast cancer
  • Onions contain several anti-cancer compounds, including quercetin, anthocyanins, organosulfur compounds such as diallyl disulfide (DDS), S-allylcysteine (SAC) and S-methylcysteine (SMC) and onionin A (ONA)
  • ONA may offer protection against epithelial ovarian cancer, the most common type of ovarian cancer; quercetin helps protect against ovarian, breast, colon, brain and lung cancer.

If you’re interested in using food to lower your risk of cancer, remember to eat lots of onions. Research shows that people with the highest consumption of onions (as well as other allium vegetables) have a lower risk of several types of cancer, including:1,2,3,4

  • Liver, colon5 and renal cell (kidney)
  • Esophageal and laryngeal
  • Prostate6 and colorectal
  • Breast7
  • Ovarian and endometrial

Onions contain several anti-cancer compounds, including quercetin, anthocyanins, organosulfur compounds such as diallyl disulfide (DDS), S-allylcysteine (SAC) and S-methylcysteine (SMC) and onionin A (ONA).

Onion Compound Suppresses Ovarian Cancer

Starting with the latter, ONA was recently found to offer protection against epithelial ovarian cancer (EOC),8 the most common type of ovarian cancer. As noted by Medical News Today:9

“With a [five]-year survival rate of approximately 40 percent, effective treatments for the illness are needed.

Although new cases of EOC ranks 10th among female malignancies, the team says the number of deaths due to this type of ovarian cancer ranks fifth in the United States.

About 80 percent of patients with EOC have a relapse after initial chemotherapy treatment.”

ONA, it turns out, slowed growth of EOC. The compound also inhibited other cancerous activities, and enhanced the effects of anti-cancer drugs. Mice fed ONA also lived longer. According to the authors:

“We found that ONA reduced the extent of ovarian cancer cell proliferation induced by co-culture with human macrophages. In addition, we found that ONA directly suppressed cancer cell proliferation.

Thus, ONA is considered useful for the additional treatment of patients with ovarian cancer owing to its suppression of the pro-tumor activation of [tumor-associated macrophages] and direct cytotoxicity against cancer cells.”

The Stronger an Onion’s Flavor, the More Effective Its Anti-Cancer Effects

Previous research has revealed that the stronger the flavor of the onion, the better its cancer-fighting potential. A 2004 study, in which food scientists analyzed 10 different varieties of onion, the following were found to be particularly effective against liver and colon cancer:10,11

  • Liver cancer: shallots, Western yellow onion and pungent yellow onion
  • Colon cancer: pungent yellow onion, Western yellow onion

Northern red onions were also found to be high in anti-cancer chemicals, just not quite as potent as the others listed.

Mild-flavored onions, such as Empire Sweet, Western white, Peruvian sweet and Vidalia had the lowest antioxidant activity, making them less potent in terms of anti-cancer benefits. According to lead author, Dr. Rui Hai Liu, an associate professor of food science:

“Onions are one of the richest sources of flavonoids in the human diet, and flavonoid consumption has been associated with a reduced risk of cancer, heart disease and diabetes.

Flavonoids are not only anti-cancer but also are known to be anti-bacterial, anti-viral, anti-allergenic and anti-inflammatory …

Our study of 10 onion varieties and shallots clearly shows that onions and shallots have potent antioxidant and antiproliferation activities and that the more total phenolic and flavonoid content an onion has, the stronger its antioxidant activity and protective effect.”

Quercetin — Another Potent Anti-Cancer Compound

Quercetin, another anti-cancer compound found in onions, has been shown to decrease cancer tumor initiation and inhibit the proliferation of cultured ovarian, breast and colon cancer cells. It’s also associated with a decreased risk for brain cancer,12 and a lower risk of lung cancer if you’re a smoker.13

Quercetin has also been shown to help lower blood pressure in hypertensive patients,14 and helps prevent histamine release, making quercetin-rich foods such as onions “natural antihistamines.”

Quercetin is available in supplement form, but getting this flavonoid naturally from onions makes more sense for a couple of reasons:15

  • One animal study found that animals received greater protection against oxidative stress when they consumed yellow onion in their diet, as opposed to consuming quercetin extracts.16
  • Quercetin is not degraded by low-heat cooking, such as simmering, making onion soup an easy-to-make superfood.

Other Beneficial Compounds Found in Onions

The organosulfur compounds DDS, SAC and SMC have also been found to inhibit colon and kidney cancer, in part by inducing cancer cell apoptosis (cell death), but also by inhibiting gene transcription and protecting against ultraviolet-induced immunosuppression.17Onions are also a good source of:

Fiber, which can help lower your cancer risk, especially colon cancer

Vitamin C18

Anthocyanins (red, purple and blue plant pigments found in red onions). Research has linked anthocyanins to a reduced risk for a number of diseases, including cancer, cardiovascular disease and neurological dysfunction and decline.

They also help prevent obesity and diabetes, in part by inhibiting certain enzymes in your digestive tract, and by supporting healthy blood sugar control. They have potent anti-inflammatory effects, which helps explain their protective effects against chronic disease

The Many Health Benefits of Onions

While onions are gaining a reputation for their anti-cancer properties, the more we learn about onions, the more it becomes clear they offer whole body benefits.

That is the beauty of eating whole foods, after all, because they typically contain many beneficial phytochemicals that enhance your health in numerous synergistic ways. As for onions, research has shown that including onions in your diet may offer the following benefits:19

Prevent inflammatory processes associated with asthma

Reduce symptoms associated with diabetes

Lower levels of cholesterol and triglycerides

Reduce symptoms associated with osteoporosis and improve bone health

Maintain gastrointestinal health by sustaining beneficial bacteria

Diminish replication of HIV

Reduce risk of neurodegenerative disorders

Lower your risk of cataract formation

Antimicrobial properties that may help reduce the rate of food-borne illness

Improvement of intestinal flora, improved absorption of calcium and magnesium due to the fructans they contain

Antibacterial, antifungal, antioxidant and anti-inflammatory properties

Improved heart health. The sulfur compounds have anti-clotting properties and help improve blood lipid profiles.

The allium and allyl disulphide in onions also help decrease blood vessel stiffness by enhancing nitric oxide release.

This may reduce blood pressure, inhibit platelet clot formation, and help decrease the risk of coronary artery disease, peripheral vascular diseases, and stroke

Tips for Storing and Preparing Onions

If learning about their health benefits has inspired you to eat more onions, you’re in luck as they are incredibly versatile and come in a variety of colors and flavors. Keep in mind that the antioxidants tend to be most concentrated in the OUTER layers of the onion, so avoid overpeeling.

Ideally, peel off only the outermost paper-like layer. Peeling too many layers can reduce the onion’s quercetin and anthocyanin content by as much as 20 percent and 75 percent respectively.20 One piece of good news is that quercetin does not degrade when cooked over low heat, so when you’re making soup, for example, it simply transfers into the broth.

As for storing your onions, do NOT keep them in plastic. Whole, dry bulbs should be stored in a cool, dry and dark place with plenty of air movement to maximize shelf life.

To extend shelf life of sweet or mild onion varieties, which have a higher water content, you can store the whole bulbs in the fridge. Once an onion has been cut or peeled, it can be refrigerated in a sealed container for about a week before it starts going bad. Leaving a cut onion in room temperature can significantly reduce its antibacterial properties.21

Cooking With Onions

The video above demonstrates the best way to peel and dice an onion, while the chart below, both from the National Onion Association (NOA),22 provides a helpful summary of which types of onions are best used for various dishes.

Color Variety or Type Availability Raw Flavor/Texture Best Usage

Yellow Onion:

All-purpose and most popular. The most well-known sweet onions are yellow.

The best type of onion for caramelizing is a yellow storage variety.

Cooking brings out this variety’s nutty, mellow, often sweet, quality when caramelized.

Sweet

March to September

Crisp, juicy, mild flavor with a slightly sweet ending with little to no after-taste

Raw, lightly cooked, sautéed or grilled

Fresh, Mild

March to August

Crisp, juicy, mild to slightly pungent with a faint after-taste

Raw, lightly cooked, sautéed or grilled

Storage

August to May

Strong onion flavor, mild after-taste

Grilled, sautéed, caramelized, baked or roasted

Red Onion:

Red onions have gained popularity in the past decade, especially in foodservice on salads and sandwiches because of their color.

Sweet

March to September

Crisp, very mild onion flavor

Raw, grilled or roasted

Fresh, Mild

March to September

Bright tones, slightly less water content than yellow with a slightly pungent ending

Raw, grilled or roasted

Storage

August to May

Sharp, spicy and moderate to very pungent

Raw, grilled or roasted

White Onion:

White onions are commonly used in white sauces, potato and pasta salads and in Mexican or Southwest cuisine.

Due to the compact nature of their cell structure, white onions do not store quite as long as other varieties.

Fresh, Mild

March to August

Moderately pungent and clean finish, very little after-taste

Raw, grilled, sautéed or lightly cooked

Storage

August to May

Moderately pungent to very pungent and full flavored, but finishes with a cleaner and crisper flavor in comparison to yellow and red storage varieties

Raw, grilled, sautéed or lightly cooked

Source: National Onion Association, All About Onions

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Turmeric Curcumin for Prediabetes


“Curcumin extract for prevention of type 2 diabetes” is an extraordinary study published in the journal of the American Diabetes Association. In this randomized, double-blind, placebo-controlled trial of folks diagnosed with prediabetes, half of the subjects got supplements of curcumin, the yellow pigment in the spice turmeric and curry powder, while the other half got identical-looking placebos, and the researchers just followed them for nine months to see who ended up with diabetes.

After nine months of treatment, 16 percent of subjects in the placebo group went on to get full-blown diabetes. How many in the curcumin group? None. The curcumin group saw a significant improvement in fasting blood sugars, glucose tolerance, hemoglobin A1C, insulin sensitivity, pancreatic insulin-producing beta cell function (measured two different ways), and insulin sensitivity.

What if you already have diabetes? Another study found the same beneficial effects—and at a fraction of the dose. The prediabetes study mentioned above used the equivalent of a quarter cup of turmeric a day, whereas this other study used only about a teaspoon’s worth, which is doable through diet rather than supplements.

What’s particularly interesting here is the purported mechanism: Fat in the bloodstream plays “an important role in the development of insulin resistance and ultimately type 2 diabetes.” Fat builds up inside your muscle cells and gums up the works, and all the inflammation interferes with insulin signaling. However, curcumin decreases fat levels in the blood, making this the first study to show that these turmeric spice compounds may have an anti-diabetic effect.

So, if you are pre-diabetic, it might be a good idea to add turmeric to your diet, but it’s important to recognize that prediabetes is a disease in itself, increasing the risk of death, cancer, heart disease, and vision loss. So, it’s not enough to just prevent progression to full-blown diabetes when prediabetes may be cured completely with a healthy plant-based diet.

Healing the Womb: The Body’s Energetic Power Centre


As we awaken individually and collectively, we have begun the task of consciously reconnecting to two vital energy centres that are allowing us to shift out of the dualistic mind into our intuition and capacity for love. These are the pineal gland or Third Eye, and the Heart. As we embrace certain spiritual practices including certain forms of meditation, yoga and shamanic medicine work we are supporting ourselves to open and heal these two centres.

This shift into our intuitive, Heart-centred consciousness is allowing us to access multidimensional realities, forge unconditional love for ourselves and each other, and reawaken our deep connection to the unified field of consciousness that is our universe. This is already a giant leap for humanity.

However, for some of us there is an important puzzle piece missing in the story of our awakening journey. This puzzle piece is a deeper centre of power within us that I call the Womb. In women whose womb organ is present, the Womb is a centre of energy and consciousness that includes the vibrational aspect of the sexual organs and physical womb. However, all of us have an energetic centre of consciousness that we can call the Womb. This includes women who no longer have a physical womb. In men the Womb is also knows as the Hara (a Japanese energy term).

 Healing the Womb The Body's Energetic Power Centre

For the purposes of clarity in this article I will refer to “Womb” to describe this energetic centre of consciousness while any reference to the physical womb organ will be done in lower case: “womb”.

I  will also clarify that by talking about the Womb I am not referring to the “sacral chakra” even through physically the Womb and sacral chakra do coincide. My reference to the Womb is as a deep and organic centre of consciousness that operates on multiple physical, mental, emotional and energetic levels.

The Womb, as a centre of consciousness, represents our foundation of personal power during the period of our physical incarnation. The vibrational frequency of the Womb is relatively dense and sits very close to the frequency of our physical bodies. When the Womb is energetically healthy and strong, this reflects in us directly through our physical health and particularly the health of our sexual organs and the deep emotional structures of the pelvis including the Psoas (known as the muscle of the soul).

Clear and healthy Womb energy contributes to a deep sense of grounding and belonging within our physical bodies. For those of us who have been lucky enough to awaken our intuition and move into our Hearts, the Womb represents the next vital step back to ourselves: the return to fully inhabiting our bodies and our feeling of deep emotional security and groundedness in our everyday lives. The healed and compete Womb holds our divinely balanced sexual energies which are also the fountain of our creativity and inspiration.

To sum up briefly, let´s say that if the Third Eye and Heart are here to open us to the truth of the multidimensional universe and connect to it through love, then the Womb is the key to our ability to experience deeper levels of personal wellbeing in our bodies and everyday human lives, and gracefully translate our spiritual truth into the grounded and real actions that will restore humanity and the Earth to their highest potential.

Individual and Collective Womb Trauma

However, the problem is that many of us are disconnected from this foundation centre of power. The reasons for this are manifold, but one of the most fundamental reason is that the Womb has sustained multiple levels of wounding at the individual, historical and collective levels. This wounding has led to us holding embedded trauma in our Womb energy- and at a psychological level the very definition of trauma is that it´s an event that takes us beyond our ability to cope.

In our individual lifetimes many of us have sustained Womb trauma including:

  • Sexual violence and abuse, or distorted and unloving sexuality
  • Difficult childbirth, abortion, miscarriage and resulting Womb trauma and grief
  • Slavery (historically feudal peasant slavery and now debt slavery and office slavery) leading to deep survival stress and the fear of not having enough

Healing the Womb The Body's Energetic Power Centre - Trauma

Our Wombs also hold historically and collectively remembered trauma, due to the fact that each of us sits in our mother´s physical womb for 9 months, during which time we are receiving and imprinting the energy of her Womb trauma, and in turn the trauma of her mother and grandmother.

As this has happened from one generation to another all the way down our ancestral lineage, we are ultimately encoding layers of historical trauma from an incredibly violent period of human history where rape, military rape, sexual torture, war and slavery have been (and in many places still are) commonplace and normalised.

When we go deeper into the Womb we uncover the memory the original trauma of mankind – the memory of being  uprooted from our rightful sovereign and abundant relationship to the Earth and each other (see “The Fall” by Steve Taylor for a fuller historical description of this trauma). The Womb remembers this and this memory is encoded in our bodies at a cellular level.

The way that we can manifest our Womb trauma can include:

  • Unhealthy or abusive sexual relationships, and low sexual or physical drive and self-esteem
  • Being overly mind or intellect driven or “spaced out” and ungrounded
  • Physical illness in the Womb area including (in women) fibroids, endometriosis and (in men) prostate cancer

How We Avoid our Womb Trauma

The pain in the Womb can be so deep that many of us are unconsciously avoiding the pain of the Womb trauma within us. It feels unsafe to arrive in this deep centre of consciousness and power because doing so may open a Pandora´s box of unresolved emotions and energies.  We may unconsciously employ all sorts of strategies for “trauma avoidance” which compound our lack of manifestation power and leave us personally and physically ungrounded. These strategies include:

  • Adopting spiritual practices that keep us centred in our “higher” centres of consciousness but disconnected from our physical bodies
  • Absorbing ourselves in information, theories and ideas or being addicted to screens and technology
  • Avoiding dealing with key issues in our lives including our physical health, sexual relationships and wealth

In my practice I have met very few adult humans who are naturally in full conscious contact with their Womb and therefore harnessing their full creative power through a grounded connection to their sexuality, their bodies and the Earth. I have seen Womb trauma play out in manifold ways in both women and men at all ages and from all walks of life.

It´s Time to Heal Our Womb Power

However the good news is that there´s never been a better time to heal our past traumas including our Womb trauma. The individual and collective wounds that may have overwhelmed us in this lifetime and are also embedded within us from our ancestral lines are now coming to the surface – not to re-traumatise us – but to be healed. We can harness the power of our Hearts and Higher Selves to bring ourselves the deep love and wisdom that is needed to heal our deepest wounds.

Ultimately the Womb begins to heal when we hold a clear intention to heal the traumas she holds at the physical, emotional, mental and energetic levels. We need to firmly commit to arriving in this deep part of ourselves however uncomfortable that journey may be. It will require us to acknowledge the ancient pain, distortion and disconnection that we have suffered for millennia upon this planet.

However, when we dive into ourselves and complete healing Womb trauma at the subtle and cellular levels the rewards are vast and in fact endless. We are gifted with a vital sense of embodiment and power in our lives. We reprogram ourselves in our sexual and intimate relationships. We begin to harness our true creative gifts. We reconnect to our sense of fundamental security and belonging on Earth.

Healing the stored trauma of the Womb and deepening into this centre of power is the next crucial step towards declaring our human sovereignty as creator beings. Because once we learn to hold our higher vision and our love for life then our next step will be to create the healing and changes where they are most needed – here and now in our every day lives on the physical plane of our beloved planet.

Source:wakeup-world.com

Reverse Cancer with Targeted Mitochondrial Restoration


The black-or-white extremism of conventional medicine needs to be redacted in favor of a more nuanced view of oncogenesis—one where cancer represents a spectrum of deviation from the norm, where carcinogenesis is an adaptive response to a radically divergent environment from the one in which we evolved.

Instead of a cell gone rogue, where cancer is caused by the accumulation of point mutations in genes controlling the cell cycle and proliferation, cancer represents a reincarnation of a more ancient survival mechanism whereby cells coordinate their behavior to survive in an increasingly harsh cellular milieu. In this view, cancer represents a regression to a pre-programmed ancestral time, before the evolution of complex, highly differentiated eukaryotic organisms, where the hostile environment would have selected for traits favoring cellular immortalization, or resistance to apoptosis, as a primitive form of survival mode emphasizing replication, self-repair, and metastasis (1). In particular, the bio-energetic and metabolic theories of carcinogenesis, advanced by the luminaries Dr. Michael Gonzalez, Dr. Dominic D’Agostino, Dr. Garth Nicolson, and Dr. Thomas Seyfried, are perfectly situated to explain the role of mitochondria, our energetic cellular powerhouses, in cancer (2).

Mitochondria: The Conductors of the Physiological Orchestra

Mitochondria are rod-shaped, double-membrane organelles responsible for production of adenosine triphosphate (ATP), the cellular energy currency that powers metabolic reactions (3). In addition to transforming organic material into ATP, mitochondria are intimately involved in heme, amino acid, lipid, and steroid synthesis, in optimal functioning of the energetically demanding immune and nervous systems, and in dictating cell fates (4). Mitochondria mediate cellular proliferation, and regulate the energetically intensive process of apoptosis, or cell suicide, via release of cytochrome c through the mitochondrial permeability transition pore (mtPTP) (5).

Apoptosis, or the coordinated collapse of the cell, is accompanied by energy-dependent signaling cascades that result in predictable morphological changes, cellular dismantling, and engulfment of the cellular corpses by neighboring phagocytes (6). Although aberrant apoptosis is implicated in disease pathophysiology, apoptosis is essential to development and homeostasis (7). In contrast, necrosis occurs secondary to cellular injury, and results in cellular swelling, membrane fracture, and complement-mediated lysis, causing release of intracellular components and consequent inflammation. Mitochondrial function is so inextricably tied to apoptosis that tissue necrosis is one of the clinical features of mitochondrial diseases, such that extensive tissue damage can be incurred (8).

Via their production of reactive oxygen species (ROS) as metabolic byproducts, mitochondria also regulate the cellular redox state. Although often vilified for perpetuating the inflammatory molecular mechanisms underlying the pathogenesis of disease, elevated levels of ROS also serve adaptive and hormetic roles as signaling molecules in redox biology for maintenance of homeostasis (9). In fact, it is theorized that ROS evolved as a signal transduction mechanism to activate transcription factors that enable adaptation to changes in accessibility of environmental nutrients and in the oxidative environment (10, 11).

Although somatic cells can contain anywhere from two hundred to two thousand mitochondria, energy requirements dictate how many mitochondria each cell contains (12, 13). The most metabolically active cells, such as those within the brain, liver, skeletal muscle, and cardiac muscle, contain the largest number of mitochondria, whereas mature erythrocytes, or red blood cells, are the only cells devoid of mitochondria (14, 15).

The Evolutionary Origins of Mitochondria

The inner mitochondrial membrane contains the metabolic machinery for aerobic metabolism, an evolutionary adaptation to oxygen-rich environments, which coincided with the endosymbiosis, or engulfment, of the ancient autotrophic bacteria that were the predecessors of these eukaryotic organelles. One to three billion years ago, aerobic bacteria colonized an ancient prokaryote, generating energy for the host cell in return for shelter and a reliable supply of food, which was the genesis of intracellular mitochondria (5, 16).

Mitochondria produce over ninety percent of cellular energy via oxidative phosphorylation, a process that couples glucose oxidation to an electron transport chain and to the flow of protons down a gradient, which results in ATP synthesis via a rotary engine of the cell called ATP synthetase (4). Pyruvate, a downstream product of cytosol-based glycolysis, along with fatty acids, are imported into the mitochondria and processed via the tricarboxylic acid (TCA) or citric acid cycle into high-energy reduced coenzymes, nicotinamide adenine dinucleotide (NADH) and flavin adenine dinucleotide (FADH2), which consequently donate electrons into the electron transport chain (ETC) in the production of ATP (17). Electrons are successively passed down an electrochemical gradient to the final electron acceptor, diatomic oxygen (O2), via a chain of respiratory proton pumps embedded in the inner mitochondrial membrane, which is why humans need oxygen to survive (18).

The fact that mitochondria have distinct, bacteria-like circular genomes that are functionally and structurally disparate from the chromosomal assemblies residing in the nucleus supports the endosymbiosis hypothesis (19). Because most of the mitochondrial genome is scattered throughout chromosomal DNA, the mitochondria is referred to as a semi-autonomous organelle, as it relies on communication with the nucleus for expression of all its enzyme complexes and molecular constituents (5). Mitochondria, which are inherited in maternal fashion, “divide by binary fission and propagate distinct ‘lineages’ within each cell” (19, p. 269). However, unlike nuclear DNA, mitochondrial DNA (mtDNA) lacks protective histones, and hence is particularly susceptible to DNA damage from free radicals (20).

Thus, mitochondrial dysfunction has been increasingly linked to almost all pathologic and toxicologic conditions, including, “A wide range of seemingly unrelated disorders, such as schizophrenia, bipolar disease, dementia, Alzheimer’s disease, epilepsy, migraine headaches, strokes, neuropathic pain, Parkinson’s disease, ataxia, transient ischemic attack, cardiomyopathy, coronary artery disease, chronic fatigue syndrome, fibromyalgia, retinitis pigmentosa, diabetes, hepatitis C, and primary biliary cirrhosis” (3, 15, p. 84). Recently, however, pioneering researchers such as Michael Gonzalez and colleagues have elucidated a unified theory of carcinogenesis where mitochondria are at the nexus of dysfunction in cancer pathogenesis (2).

Cancer As A Pre-Symbiotic, Primordial State

Emerging data, which considers malignancy through an ecological lens, recognizes cancer not as a predetermined genetic time bomb due to defective genes, but rather as an evolutionary throwback to a time where more rudimentary cooperation between free-floating cells existed, which allowed their survival in nutrient depleted, increasingly uninhabitable environments. This view is articulated by Davies and Lineweaver (2011), who state,

“We hypothesize that cancer is an atavistic condition that occurs when genetic or epigenetic malfunction unlocks an ancient ‘toolkit’ of pre-existing adaptations, re-establishing the dominance of an earlier layer of genes that controlled loose-knit colonies of only partially differentiated cells, similar to tumors” (1).

This is similarly articulated by Davila and Zamorano (2013), who discuss how, “Some of the hallmarks of cancer such as uncontrolled cell proliferation, lack of apoptosis, hypoxia, fermentative metabolism and free cell motility (metastasis) are akin to a prokaryotic lifestyle, suggesting a link between cancer disease and evolution” (21). They note that cancer represents a phenotypic reversion to the most preliminary stage of eukaryotic evolution, that of a heterotrophic, facultative anaerobe that is suited for survival and replication in oxygen-poor, hypoxic environments (21). The authors state that this occurs due to cumulative oxidative damage to both maternally inherited mtDNA and nuclear DNA and to mitochondrial insufficiency, or uncoupling between electron transfer and chemiosmotic ATP synthesis (21).

In particular, the bioenergetic theory of carcinogenesis proposed by Gonzalez and colleagues proposes that the replacement of oxygen-dependent aerobic respiration by aerobic glycolysis and lactic-acid producing fermentation, phenomena first characterized in cancer cells over ninety years ago by Nobel Laureate Otto Warburg, favors carcinogenesis (2). In the hypoxic micro-environment in which cancer develops, a metabolic transition from obligate anaerobe to partial anaerobe, accompanied by enhanced glycolytic flux, takes place, which ensures survival in oxygen-poor conditions (22).

The switch from mitochondrial-based glucose oxidation to cytosol-based aerobic glycolysis, or glycolysis in the presence of oxygen, is why positron emission tomography (PET) scans can be used to localize tumors and metastases, since the labeled glucose gravitates towards malignant tissue with a high rate of glycolysis (2). The propensity of tumor cells for increased glycolytic flux also confers resistance to apoptosis, or programmed cell death, which allows cancer cells to evade cell suicide signals (23, 24). Without electron flow down the ETC, mitochondria also lack the energy for depolarization and synthesis of reactive oxygen species (ROS), which are crucial redox signals required for apoptosis (25, 26).

Cancer Thrives in An Acidic Body

As a corollary, cancer cells lack superoxide dismutase (SOD), one of the endogenous antioxidant defense systems that protects mitochondrial genes and proteins from the free radical byproducts of the citric acid cycle (27). As a result, free radicals impair the citric acid cycle and pyruvate is instead shuttled into lactic acid, perpetuating lactic acidosis. In fact, when succinate, a tricarboxylic acid (TCA) cycle intermediate, is added to cancer cell lines, the rate of respiration remains stagnant, which demonstrates that cancer cells cannot utilize the citric acid cycle (17).

In particular, fermentation by malignant cells facilitates the generation of acidic pH in cancerous tissues due to lactic acid production, a hallmark of aggressive cancer growth (22, 28). Production of lactate begins to dwarf that of pyruvate, which results in less activity of the TCA cycle, and less generation of the energized intermediates NADH and FADH2 to fuel oxidative phosphorylation (2). What’s more, lactate accumulation promotes tumor growth by activating angiogenesis, or the formation of new blood cells to supply the tumor with nutrients, and by degrading extracellular matrix, which allows tumor expansion and augments potential for metastasis (29).

In addition, the adverse change in pH engender voltage differences in cell membranes, which may disrupt communication, cause electrical uncoupling, induce mitosis, and lead to further derangements in proton and electron efflux (2). Further, membrane potential disruption and consequent accumulation of a surplus of negative ions in the extracellular milieu repels erythrocytes and lymphocytes, shielding cancer cells from oxygen- and immune-mediated destruction, respectively (2). This sequestering effect and decrease in immune reactivity is compounded by the formation of coagulated proteins around transformed cells, which in turn prohibits access of host immune defenses to combat cancer (2).

Compared to the complete aerobic oxidation of glucose, which generates 38 ATP per mole of glucose, substrate-level phosphorylation via glycolysis is relatively energy inefficient, yielding only 2 ATP per mole of glucose (2). In addition to diminished internal resources of the malignant cell due to preferential use of glycolysis, cancer interferes with electrical impedance, sodium-potassium membrane pump function, and the enzymes of the respiratory complexes embedded within the inner mitochondrial membrane, such that intercellular communication and membrane dynamics are jeopardized (2, 30).

These metabolic limitations, in concert with the decreased mitochondrial content, lead to an enormous reduction in energy reserve, with the average cancer cell having less than one-twentieth the energy of a healthy cell (2). Hypoxia-inducible factor (HIF), which is activated as a consequence of the hypoxic microenvironment in which cancer develops, up-regulates expression of glucose receptors and glycolytic enzymes in attempt to reflexively compensate for the diminished efficiency of glycolysis compared to oxidative phosphorylation (31).

In sum, incessant cellular insult, as a result of the micronutrient depletion, sedentary lifestyle, psychosocial stress, and toxicant exposure to which most of us are subjected, culminates in a transformed cell phenotype where cellular apoptotic mechanisms are compromised and cellular metabolism becomes deranged. Hence, cancer arrives on the scene as an adaptation to the traumatic living circumstances of modernity.

Mitochondrial Metabolic Correction

Restoration of mitochondrial function is of the utmost importance, since mitochondrial remodeling, or mitochondrial dysbiosis, defined as the process whereby “mitochondria can dissolve their symbiosis with the cell host, and no longer function in harmony with the cell,” is a distal molecular pathway common to all cancer cells (29, 2, p. 436). Instead of treating cancer like a foreign entity to be eradicated, cancer should be re-conceptualized as cells that have lost their way, and have begun operating as unicellular, independent entities, profligately replicating and forming a protista colony of sorts as a survival mechanism (2). In this model, cells need to be supplied with the proper conditions to be coaxed back to their normal phenotype, re-differentiate, and regain local tissue communication and architecture.

Dr. Michael Gonzalez and colleagues reiterate these foundational principles of Nobel laureate Szent-Györgyi with, “Efficient oxidative energy production is associated with organized cell structure, whereas fermentation is associated with lack of structure and the inclination to cell division” (2, p. 437). Because the cardinal difference between normal and cancer cells is the use of fermentation by the latter to meet energy demands, restoring aerobic respiration, or correcting mitochondrial function to promote induction of apoptosis in cancer cells, should be clinical priorities, rather than decimating the very immune defenses that fight cancer with radiation and chemotherapy.

Therefore, undertaking a program of mitochondrial correction, including a nutrient-dense, paleolithic diet to which our physiology is accustomed, and nutraceuticals needed for aerobic respiration, repolarization, and membrane repair, could potentially reverse cancer (2). This phenomenon is illustrated by the observation that suppression of mitochondria promotes cancer growth in normal cells, whereas inhibition of glycolysis leads to rapid death of cancer cells (2). Likewise, animal models and in vitro studies have illuminated decreased rates of tumor growth with normalization of mitochondrial function (32).

Dietary Considerations for Mitochondrial Renewal

A primarily plant-based paleo diet rich in fruits and vegetables and devoid of processed foods, high-glycemic foods, flour, sugar, coffee, and alcohol, will promote blood alkalinity, which is important since alkaline solutions favor oxygen absorption, whereas acidic solutions favor oxygen release (2). Mitochondrial matrix enzymes operate best in an alkaline environment, whereas acidity disturbs membrane potential, resulting in cellular malfunction, compromised energy production, and carcinogenesis (33, 34, 35). A nutrient-dense, phytonutrient-replete diet will provide the blood with the minerals to maintain an alkaline pH and to retain oxygen(2).

A high fat, low carbohydrate ketogenic paleo template diet is ideal, since ketogenic diets increase circulating ketone bodies while decreasing blood glucose levels, thus restricting energy supplied to cancer cells (36). Ketones, which bypass glycolysis and enter the mitochondria directly for oxidation, are a viable alternative energy source for wild-type cells with normal mitochondrial function, but cannot be utilized by cancer cells since they lack metabolic flexibility (37, 38, 39). Furthermore, ketone bodies are inherently anti-inflammatory, reducing ROS while augmenting activity of glutathione peroxidase, one of the endogenous antioxidant defense systems (37, 40).

In addition, ketogenic diets are often accompanied by dietary energy reduction (DER), which elicits anti-cancer effects through inhibition of the IGF-1/PI3K/Akt/HIF-1alpha pathway that cancer cells hijack to suppress apoptosis and to engender proliferation and angiogenesis (36). DER induces apoptosis in astrocytoma cells and has demonstrated anti-tumor effects in brain, colon, gastric, lung, mammary, prostate, and pancreatic cancer (36). The ketogenic diet administered in restricted amounts also significantly improves health and longevity of mice with malignant brain tumors relative to controls receiving a low fat high carbohydrate diet (40). The calorie-restricted ketogenic diet likewise decreases micro-vessel density in tumors and has been shown to lead to 65% and 35% lower orthotropic growth rates of implanted malignant mouse astrocytoma and human malignant gliomas, respectively, in animal models (40).

Hyperbaric Oxygen Therapy

In light of the observations that white blood cells kill cancer cells by injecting them with oxygen in the form of hydrogen peroxide, and that depleting oxygen induces cellular mutation, one of the clinical objectives of cancer treatment should be increasing cellular oxygenation (2). Promoting oxygenation, and hence better detoxification, through therapies such as hyperbaric oxygen therapy (HBOT), will promote down-regulation of the expression of cancer-related genes such as HIF-1 (41).

Poff and colleagues (2013) elucidate how, “Abnormal tumor vasculature creates hypoxic pockets which promote cancer progression and further increase the glycolytic-dependency of cancers” (36, p. e65522). Tumor hypoxia not only renders cancer cells three-times as resistant to radiation therapy than well-oxygenated cells, but it also stimulates oncogenic biochemical pathways that facilitate tumor growth, angiogenesis, metastasis, and inhibition of apoptosis via the transcription factor HIF-1 (42, 43, 44). Saturating the tumors with hyperbaric oxygen chamber therapy, in contrast, enables adequate tissue perfusion, effectively reversing the cancer-permissive effects of hypoxia (36).

In addition to inhibiting tumor growth, depleting blood vessel density within mutated cells, and promoting expression of anti-cancer genes in animal models, hyperbaric oxygen therapy up-regulates production of ROS by tumor cells to enhance efficacy of the standards of care (36). In a mouse model of metastatic cancer, the ketogenic diet in concert with hyperbaric oxygen therapy led to significant decreases in blood glucose and tumor growth rate and produced a 77.0% average increase in survival time compared to controls (36). Quintessentially, by increasing delivery of oxygen to tissues independent of hemoglobin oxygen saturation, hyperbaric oxygen therapy has the potential to restore aerobic respiration over the substrate-level phosphorylation that occurs in glycolysis (45).

Targeted Nutraceuticals

Furthermore, a cancer-mitigating diet should be rich in micronutrients needed to sustain the biochemical pathways that extract and convert energy from organic molecules into biologically accessible forms (4). Restoration of oxidative respiration will cause the synthesis of oxidation byproducts, which normally translocate from the cytosol to the nucleus, influencing gene expression in a way favoring re-differentiation away from the primitive mutagenic phenotype (46).

Targeted orthomolecular use of mitochondrial support, such as alpha lipoic acid, acetyl-L-carnitine, coenzyme Q10, magnesium, D-ribose, PQQ, creatine, and B complex may also be warranted (4). Phospholipids replacement therapy is also integral to mitochondrial repair since damage to the lipid bilayer and to the dual-layered mitochondrial membrane precedes mitochondrial damage (47).  Further, ascorbate, or vitamin C, administered intravenously in particular, may restore normal apoptosis in cancer cells by augmenting electron flux, increasing generation of ATP, and facilitating re-differentiation to a normal phenotype (4, 33).\

Removal of Offending Agents

Lastly, exposure to mitochondrial toxicants, such as xenobiotics and persistent organic pollutants which damage the mitochondrial membrane, should be minimized (4). Importantly, medications such as psychotropic drugs, analgesics, anti-inflammatory agents, antibiotics, anticonvulsants, statins, steroids, chemotherapy, and drugs for diabetes and HIV/AIDS are major contributors to mitochondrial damage (4). Although many medication side effects and drug-induced toxicities are a direct consequence of mitochondrial dysfunction, the U.S. Food and Drug Administration (FDA) still does not mandate mitochondrial toxicity testing for pharmaceuticals (48).

According to Neustadt and Pieczenik (2007), medications can directly disable elements of the electron transport chain, inhibit transcription of electron transport chain complexes, or inhibit the enzymatic processes involved in beta-oxidation or glycolysis. Pharmaceutical drugs can also deplete endogenous antioxidants or nutrients required for mitochondrial function, or generate free radicals which damage mitochondrial structures (3).

Where Oncology is Failing, Mitochondrial Regeneration Can Succeed

The decision to use toxic chemotherapy, radiation, or trauma-inducing surgery—the only legally sanctioned cancer therapies, fraught with conflicts of interest and vested fiscal agendas—is a personal one, and should be made in concert with a licensed physician and your intuition as a guide. However, studies have shown that the percentage increase in five-year survival rate due to adjuvant and curative cytotoxic chemotherapy is only 2.1% in the United States and 2.3% in Australia (49). Another comprehensive analysis of over 3,000 clinical trials determined that there is no direct evidence that chemotherapy prolongs survival in advanced carcinoma, apart from small-cell lung cancer (50).

Researchers state, “Many oncologists take it for granted that response to therapy prolongs survival, an opinion which is based on a fallacy and which is not supported by clinical studies” (50). In other words, tumor shrinkage does not translate into survival advantages over ‘watch and wait’ approaches in many cancers (51). Further, because chemotherapy and radiation do not target the self-renewing cancer progenitor cells known as cancer stem cells, secondary cancers that re-emerge are usually more aggressive and fatal. In fact, radiation generates therapy-resistant cancer stem cells, such that lingering cancer cells become more malignant (52).

A more holistic vantage point should be adopted regardless of the therapies a cancer patient employs, addressing latent infections, micronutrient and fatty acid deficiencies, hormonal imbalances, toxicant exposures, dysbiosis, inflammatory underpinnings, psychospiritual stress, and mitochondrial insufficiency, all of which contribute to a hostile, threatening environment which cause cells to harken back to a pathological, undifferentiated, cancerous phenotype.

Researcher and clinician Dr. Michael Gonzalez, who is using some of these targeted therapies in his clinic, has witnessed better quality of life and increased survival time in cancer patients compared to use of conventional therapies alone. He states, “I truly believe that the bioenergetic theory of carcinogenesis describe the root of cancer…and will pave the way for a new understanding of cancer as a metabolic mitochondrial disease, leading to more effective, less toxic, and user-friendly treatments”.

source:http://www.greenmedinfo.com

Yoga more dangerous than previously thought, scientists say


A yoga class

Yoga is more dangerous than previously thought and causes as many injuries as other sports, a study has found.

The 5,000 year-old Indian discipline is said to boost physical and mental wellbeing, and celebrity fans include Beyonce, Lady Gaga and Brazilian supermodel Gisele Bundchen – as well as David and Victoria Beckham.

However, in a recent study yoga caused musculoskeletal pain – mostly in the arms – in more than one in ten participants.

A class using yoga belts
A class using yoga belts 

The scientists behind the research, which was published in the Journal of Bodywork and Movement Therapies, also found that the practice worsened over a fifth of existing injuries.

Professor Evangelos Pappas, of Sydney University, the study’s lead researcher said: “Yoga may be a bit more dangerous than previously thought.

“Our study found the incidence of pain caused by yoga is more than 10 percent per year – which is comparable to the rate of all sports injuries combined among the physically active population.

“However people consider it to be a very safe activity. This injury rate is up to 10 times higher than has previously been reported.”

His team assessed more than 350 people who attended yoga classes at two studios in New York.

Yoga is an increasingly popular complementary or alternative therapy for musculoskeletal disorders, with millions of people practising worldwide.

 Prof Pappas said: “While yoga can be beneficial for musculoskeletal pain, like any form of exercise, it can also result in musculoskeletal pain.”

He added: “We also found yoga can exacerbate existing pain, with 21 per cent of existing injuries made worse by doing yoga, particularly pre-existing musculoskeletal pain in the upper limbs.

In terms of severity, more than one-third of cases of pain caused by yoga were serious enough to prevent yoga participation and lasted more than 3 months.

“The study found that most ‘new’ yoga pain was in the upper extremities – shoulder, elbow, wrist, hand – possibly due to downward dog and similar postures that put weight on the upper limbs.”

The study conducted with Prof Marc Campo from Mercy College, New York, asked participants to complete an electronic questionnaire at the start of the project and again one year later.

Outcomes included incidence and impact of pain caused by yoga and prevalence of pain caused, exacerbated, unaffected, and improved by the ancient practice.

Prof Pappas said: “It’s not all bad news, however, as 74 per cent of participants in the study reported that existing pain was improved by yoga, highlighting the complex relationship between musculoskeletal pain andyoga practice.

“These findings can be useful for clinicians and individuals to compare the risks of yoga to other exercise enabling them to make informed decisions about which types of activity are best.

“Pain caused by yoga might be prevented by careful performance and participants telling their yoga teachers of injuries they may have prior to participation, as well as informing their healthcare professionals about their yoga practice.

“We recommend that yoga teachers also discuss with their students the risks for injury if not practised conscientiously, and the potential for yoga to exacerbate some injuries.

“Yoga participants are encouraged to discuss the risks of injury and any pre-existing pain, especially in the upper limbs, with yoga teachers and physiotherapists to explore posture modifications that may results in safer practice.”

The main components of yoga are postures, a series of movements designed to increase strength, flexibility and breathing.

It’s now commonplace in leisure centres, health clubs, schools, hospitals and surgeries.

There’s some evidence that regular yoga practice is beneficial for people with high blood pressure, heart disease, aches and pains – including lower back pain – depression and stress.

The NHS says most forms of yoga are not strenuous enough to count towards your 150 minutes of moderate activity, as set out by government guidelines.

However, yoga does count as a strengthening exercise, and at least two sessions a week will help you meet the guidelines on muscle-strengthening activities.

Activities such as yoga and tai chi are also recommended to older adults at risk of falls to help improve balance and co-ordination.

8 Buddhist habits that will change your life


Some of the happiest people on earth are Buddhist monks. They practice living in a different way than we do, and adopting their habits can have a positive effect on our own happiness.

Buddhism is an extremely mindful practice. They focus on living simply and rule out all materialistic complications. Buddhism has been becoming increasingly popular too. We are seeing more and more people in the eastern society adopting the ways of Buddhist monks because it offers answers and solutions to modern world problems. Buddhism additionally gives us another point of view on who we really are. They think very highly of the human spirit and they appreciate all walks of life.

If you are looking to get away from all the hustle and bustle complications of the modern day world, Buddhist practices may be your out. It makes living simplistic and more meaningful. Simply adopting these habits could change your entire life.

The first habit you should adopt is to simplify. Life is not even nearly as complicated as we make it out to be. All of the problems we have were created by us and they can also be eliminated. Most people’s goal is to acquire as much stuff as they can and be as wealthy as they can, but this does not guarantee happiness. Instead, happiness comes from within, so you have all you need.

Practice Giving

Along with simplifying your life, you need to give too. Giving not only helps another human individual, but it makes us feel good too! Giving things away to help others actually releases dopamine in our brains, making us feel blissful. A selfless attitude is essential to live a Buddhist style life. Being selfless is about much more than giving to other people. If we are all selfless, we wouldn’t have so many problems. Let go of that ego and ask yourself what you can do to benefit society.

Meditate

Meditating is also a key part of Buddhism. Simply sitting down in a quiet place for ten minutes and change your entire day for the better. It’s also scientifically proven to change the brain! All you have to do is sit down, focus on your breathing, and let it all be. Chanting mantras is also a great way to keep your mind on track while meditating.

Respect and Learn from your Elders

Another Buddhist habit that is life changing is listening to people wiser than you. We don’t know it all, and as easy as it is to pretend we do, you’ll actually get a lot more out of listening to others than you think. Listen to learn, not to reply.

Go Throughout Everyday Mindfully

You will additionally want to make mindfulness a key part of your life. Being mindful doesn’t mean you go around enlightening people and meditating all the time. Being mindful is taking the time to further your spiritual growth and knowledge. Being mindful means not judging other people, getting your happiness from a natural source, and growing spiritually.

Embrace Change

Embracing change can also change your life. Change can be scary, but that doesn’t mean it is a bad thing. We are forever evolving and we change all the time. Embracing it will only make it easier for you! There is so much more to focus on in life than holding onto what we used to have.

Use Aromatherapy

Monks practice aromatherapy a good bit too. Aromatherapy using essential oils has massive amounts of benefits. Depending on the specific oil you use, they can treat health issues, promote sleep and relaxation, reduce stress, and promote creativity. It is awesome to breathe in the oil of frankincense while meditating.Live in the Moment

The most important habit that Buddhist monks have that we need to learn is living in the moment. The majority of our anger, frustration, anxiety, and sadness comes from anticipation of the future or dwelling on the past. If you can try hard enough, and it does require practice, you can live in the present only and doing so eliminates massive amounts of stress and negative emotions.

Research Proving Vitamin C’s Therapeutic Value in 200+ Diseases


Vitamin C is generally considered to be an important “nutrient,” but its perceived value usually ends there. Only rarely does the public (and the medical profession) glimpse its true potential in the prevention and treatment of disease — and this because, by legal definition (in the US), only FDA-approved drugs can prevent, treat and cure disease.

This does not mean, however, that essential nutrients like Vitamin C cannot in fact prevent and treat disease, i.e. only because it is illegal to speak truthfully about something, doesn’t mean that that something isn’t true.  The National Library of Medicine, in fact, contains thousands of studies demonstrating vitamin C‘s ability to significantly improve health, with 220 disease applications documented on the research site alone.  The best thing ‘we the people’ can do, despite our lack of medical degrees and licensure, and without the FDA’s iron-fisted legal and regulatory apparatus on our side, is to use the peer-reviewed research at our disposal to inform and protect our treatment decisions.

Perhaps we must revisit an important moment in history to regain a sense of how profoundly vitamin C deficiency and vitamin C therapy can affect health. James Lind (1716-1794), pioneer of naval hygiene in the British Royal Navy, conducted the first ever clinical trial proving that citrus fruits cured scurvy. Lind’s discovery saved tens of thousands of seamen from the ravages of scurvy, spurring England’s naval supremacy, putatively changing the course of world history.

If significant historical events like these don’t provide enough evidence to vindicate the efficacy of nutrients like Vitamin C, molecular biology and the science of genetics can help to fill in the gaps.

It is a little known and under-appreciated fact that all humans are born with a serious, life-threatening genetic defect: namely, the inability to manufacture Vitamin C.

This defect occurred approximately 63 million years ago, when our haplorrhini (“simple nosed”) primate predecessors lost the gene (Gulnolactone oxidase pseudogene – GULOP), responsible for the manufacture of Vitamin C from glucose.

The ability to synthesize Vitamin C, in fact, has been lost several times in vertebrates, e.g. in guinea pigs, some bats, some fishes, passeriform birds and in primates of the suborder Haplorrhini, which includes monkes, apes and humans.

It was Linus Pauling, two time Nobel Laureate, and the world’s foremost vitamin C proponent, who first brought this inborn error of metabolism to popular light. Pauling advocated taking large doses of Vitamin C (up to 10-12 grams a day) in order to offset the deficiencies of our modern diet. He believed that it was our movement away from a vitamin C rich fruit-and-vegetable based diet that explained the modern epidemic of heart disease.

According to this perspective, without adequate Vitamin C we are unable to produce the collagen necessary to heal our arteries. The Vitamin C starved body compensates for this by increasing the production of a very small and sticky type of cholesterol known as lipoprotein A, which leads to the formation of atheromatous plaque (clogged arteries). Linus Pauling advocated taking large amounts of vitamin C in combination with the amino acid lysine to reverse the damage done to the arteries, and to prevent recurrence.*

Indeed, a study published in 2008 showed that higher plasma vitamin C levels are associated with a significantly reduced risk of stroke. Scientists from the clinical gerontology unit at Addnbrooke’s University Hospital in Cambridge, UK, tracked 20,649 men and women aged 40 to 79 years, between 1993 and 1997. The group was followed through March 2005. Individuals who had the highest vitamin C levels showed a 42% reduction in stroke risk! If you compare this with Plavix’s 8.7 – 9.4% risk reduction, and the profound side effects drugs like these generate, one begins to understand why the media projection of “vitamins are toxic” propaganda serves only the interests of the drug companies.

Before one goes out and buys a bargain bottle of Vitamin C tablets, one should be advised that ascorbic acid is not exactly the same thing as Vitamin C. Ascorbic acid is found within the Vitamin C complex as it exists in food, but is complexed with a wide range of inseparable cofactors, such as rutin, bioflavonoids (vitamin p), protein chaperones, and various enzymes like tyrosinase, which together in their entirety constitute the whole food complex. Take the ‘vitamin c’ as isolated ascorbic acid out of the nutritional context of food and is behaves more like a chemical or drug.

Ascorbic acid is also 10 times more acidic than the naturally buffered Vitamin C found in raw food, and will on occasions lead to stomach upset, calcium loss from the bones, and kidney stones, in susceptible individuals. Traditionally ascorbic acid is produced semi-synthetically from corn or rice starch through a heavily chemical dependent process. Ascorbic acid can be considered no more natural than white flour, and yet despite this fact, has very little toxicity relative to pharmaceuticals, and can be used in much higher doses than the FDA’s Recommended Daily Allowance without adverse side effects.

The difference between ascorbic acid and Vitamin C in whole food form was perfectly clear to Szent-Gyorgi who received a Nobel Prize in 1937 for discovering Vitamin C. Even though Szent-Gyorgi received international recognition for identifying ascorbic acid as Vitamin C, his later research lead him to conclude that ascorbic acid had very little anti-scurvy activity in and of itself. Szent-Gyorgi found that the vitamin C found in organ meats and food sources like paprika, where the aforementioned cofactors are intact, were far superior in combating scurvy.

We would be well served to acknowledge that all raw fruits and vegetables contain a “life force” that can not be fully decomposed or reduced to the chemical skeleton within which the life force of “vitamin activity” works, no more than our life/soul can be reduced to the $10 or so worth of chemical building blocks that our body is composed of. Fortunately, there are vitamin manufacturers out there who acknowledge this fact, and produce raw whole food concentrates rich in vitamin activity. When eating raw, organic fruits and vegetables is not an option, or when higher levels are needed, these supplements offer authentic therapeutic activity.

The history of vitamin C illustrates just how profoundly important it is for us to get these vital nutrients known as “vitamins,” and that they are best derived from food. If we choose to overlook the importance of vitamins in maintaining health, and yes, even preventing and reversing disease, we will be forced to accept a pharmaceutically driven medical perspective that believes that health is the absence of symptoms, and that symptoms are to be combated or driven back deep into our bodies with sublethal dosages of toxic chemicals, i.e. drugs. Such a perspective on disease is itself so diseased that there is no escaping the ill health that results from it. We must remember that there has never been a disease that has been caused by a lack of a drug… therefore, why would it ever be considered sound medical practice to treat disease with drugs, as a first line of treatment?

*If Linus Pauling and other Vitamin C researchers are correct and a deficiency of Vitamin C causes the breakdown of collagen in the artery, aspirin therapy, which causes Vitamin C deficiency, would not be considered a safe way to reduce cardiac mortality. To the contrary, it would further destabilize the strength and elasticity of the artery leading to hemorrhage, which is the primary deadly side effect of aspirin therapy.

Medical Marijuana via the Rectum is Safer, More Powerful than Smoking It


 Our advocacy for marijuana is based purely on medical grounds. We don’t support people abusing the plant. Before you take marijuana, it should be on a concrete reason. The plant should serve a specific and important purpose for you – health wise.

For those in the United States who are fortunate to have access to marijuana, we recommend you consult a health expert who knows about the efficacy of the plant before taking it. We are starting this educative campaign, and will report on views of various health experts who are familiar with marijuana.  We are doing this because we certainly know marijuana will soon be accepted nationwide in the United States, and most likely, around western nations across the world.

Currently, Canada is said to be moving closer to allowing the use of marijuana. New regulations on the plant are expected to take effect this summer. Prime Minister Justin Trudeau has confirmed that a new marijuana law is ready to take effect in the country.

But before this is done, health experts are providing significant education to the Canadian public regarding how best they can make use of medical marijuana. The medical director of the Center for Integrative Medicine at George Washington University, Mikhail Kogan recently told Canadian Press in an interview that taking marijuana up the butt is actually much more effective than smoking it. Dr Kogan revealed rectal administration of the plant allows it to function effectively in the body, but because people nowadays are not comfortable with such administration of drugs, it mostly becomes difficult convincing people to attempt this method.

“Rectally is actually a lot more preferred because of the volume of absorption. You can put a lot more and it gets absorbed a lot better, but not everybody is open to this way of administration,” he said.

Dr Kogan is not the only health expert recommending Canadians take marijuana via the rectum. A dispensary based in the province of British Columbia, Kootenays Medicine Tree, has also said suppositories are a good option for people who are seriously ill; they can take large doses that activate quickly and don’t give patients a high.

Health experts supporting marijuana are recommending the rectal administration of marijuana due to some reports suggesting smoking marijuana can have adverse health effects. The Canadian Centre for Substance Abuse (CCSA) recently reported “Smoking cannabis may be even more harmful to a person’s airways and lungs than smoking tobacco, since cannabis smoking often involves unfiltered smoke, larger puffs, deeper inhalation, and longer breath holding.”

 

Although the CCSA report needs further studies, it is necessary we find another option to be able to use the plant without any adverse side effects. Therefore, health experts are recommending this method.

According to observers, Canadians would probably find it difficult to follow this recommendation. However, this isn’t new to the United States.

Vaginal marijuana suppositories that are meant to reduce menstrual pain are said to be on sale in some states where medical marijuana laws have passed in the United States.

As marijuana increasingly becomes popular in the United States, so too does its popularity in Canada. A study conducted recently revealed almost half of Canadians have used marijuana at least once in their lifetime.

 

In the United States, the number of Americans using marijuana is rising at an unprecedented rate. In 2016, a poll published by the American research company Gallup Incorporated revealed the percentage of American adults who smoke marijuana has nearly doubled in three years.

In 2013, Gallup poll revealed that 7 percent of American adults smoke marijuana, but the same poll in 2016 found the figure had increased to 13 percent. Marijuana advocates say the sharp rise in marijuana use in the country is due to successes in educating the American public about medicinal and other beneficial values of the plant. People are responding to the education and are ridding their former negative perceptions about the plant.


Read more at http://www.enlightened-consciousness.com/medical-marijuana-via-the-rectum-is-safer-more-powerful-than-smoking-it/#8Vbb6modvWT6DO6X.99

For Bad Backs, It May Be Time to Rethink Biases About Chiropractors


Spinal manipulation or physical therapy such as heat and stretches (above) seem as effective as traditional approaches to help lower back pain. 

About two of every three people will probably experience significant low back pain at some point. A physician like me might suggest any number of potential treatments and therapies. But one I never considered was a referral for spinal manipulation.

It appears I may have been mistaken. For initial treatment of lower back pain, it may be time for me (and other physicians) to rethink our biases.

Spinal manipulation — along with other less traditional therapies like heat, meditation and acupuncture — seems to be as effective as many other more medical therapies we prescribe, and as safe, if not safer.

Most back pain resolves over time, so interventions that focus on relief of symptoms and allow the body to heal are ideal. Many of these can be nonpharmacological in nature, like the work done by chiropractors or physical therapists.

Physicians are traditionally wary of spinal manipulation (applying pressure on bones and joints), in part because the practitioners are often not doctors and also because a few chiropractors have claimed they can address conditions that have little to do with the spine. Patients with back pain haven’t seemed as skeptical. A large survey of them from 2002 through 2008 found that more than 30 percent sought chiropractic care, significantly more than those who sought massage, acupuncture or homeopathy.

Researchers have been looking at the evidence supporting spinal manipulation for some time. Almost 35 years ago, a systematic review evaluated the available research, most of which was judged to be low in quality, and found that there might be some short-term benefits from the procedure. Two reviews from 2003 agreed for the most part, finding that spinal manipulation worked better than a “sham procedure”, or placebo, but no better or worse than other options.

Almost a decade later, a Cochrane review assessed the literature once more, and found 12 new trials had been conducted. This review was more damning. It found that spinal manipulation was no better than sham interventions.

But since then, data have accumulated, as more higher-quality studies have been performed. Recently, in The Journal of the American Medical Association, researchers looked for new studies since 2011, as well as those that had been performed before.

The evidence from 15 randomized controlled trials, which included more than 1,700 patients, showed that spinal manipulation caused an improvement in pain of about 10 points on a 100-point scale. The evidence from 12 randomized controlled trials — which overlapped, but not completely with the other trials — of almost 1,400 patients showed that spinal manipulation also resulted in improvements in function.

In February, in Annals of Internal Medicine, another systematic review of nonpharmacologic therapies generally agreed with the other recent trials. Based upon this review, and other evidence, the American College of Physicians released new clinical practice guidelines for the noninvasive treatment of subacute back pain. They recommended that patients should try heat, massage, acupuncture or spinal manipulation as first-line therapies.

The only things that might detract from the use of spinal manipulation in this situation would be its cost and potential harms.

Because they fear those potential harms, some physicians are hesitant to refer patients to chiropractors or physical therapists for care. But in all the studies summarized above, there were really no serious adverse events reported. It’s possible to find anecdotes of harm to the spinal cord from improper manipulations, but these are rare, and almost never involve the lower spine.

Some physicians are concerned about the cost of spinal manipulation, especially since most insurance carriers don’t cover it. Visiting a chiropractor costs more than taking many non-narcotic pain medications. But more invasive interventions can cost a lot of money. In addition, studies have shown that, in general, users of complementary and alternative medicine spend less over all for back pain than users of only traditional medicine.

Medication and surgery can also lead to harms. We shouldn’t forget that prescription pain medications, like opioids, can lead to huge costs, especially when they’re misused.

Some physicians are uncomfortable that we don’t have a clear picture of how spinal manipulation actually works to reduce pain. It’s also possible that some chiropractors do it “better” than others, and we can’t tell. This concern should be tempered by the fact that we don’t have a great understanding of why many other therapies work either. Some of the more traditional things we recommend don’t even work consistently.

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Still, there is no merit to many other claims about spinal manipulation — that it has been proved to work for things like infantile colicpainful periodsasthma, gastrointestinal problems, and more. For most conditions, the therapy lacks a good evidence base.

But given the natural course of back pain — that most of it goes away no matter what you do — the ideal approach is to treat the symptoms and let the body heal. Noninvasive therapies seem to do that well enough.

Source:www.nytimes.com

How to superchsrge your domamine level?


Did you know that we have chemicals in our brain that make us feel good? One of the most important is Dopamine (also known as the ‘feel good chemical’). Having reduced levels of dopamine can lead to adverse effects like depression and negativity.

brain dopaminee

But don’t worry, there are natural ways to increase your dopamine so you can experience a more constant level of happiness. Best of all, the following techniques don’t involve medications.

1. Exercise.

Exercise can boost your levels of endorphins, serotonin and dopamine, which will not only strengthen your muscles, but will help reduce your stress. The best bit? It works with any kind of exercise – just as long as you get moving!

 

2. Avoid Addictions.

While addictions may provide an instant boost of pleasure, it isn’t long-lasting.What eventually happens is that your base levels of dopamine will actually decrease and you will need your addiction more often. Therefore, it can beneficial to avoid addictions and focus on things that give you calm and peace.

3. Detoxification.

Toxins and unhealthy bacteria can halt your body producing dopamine, so make sure to consistently detoxify your body.


4. Increase Tyrosine.

This amino acid is one of the most important for the production of dopamine.Make sure to consume almonds, bananas, dark chocolate and green tea.

5. Music

Music actually increases your feel good chemicals, so make sure to regularly listen to music you enjoy.

6. Organize your life.

When you complete a goal, dopamine levels are increased. Therefore, write down your tasks, even small ones, and tick them off once you complete them. Every time you finish a task, you’ll experience a small rush of dopamine for completing your goal.

7. Creativity.

Being creative releases dopamine. The great thing is creativity can be found in a whole range of tasks from writng to singing to dancing.

8. Get a streak going.

This is a visual display of the number of times you achieve something. Again, by displaying things you achieve, your brain will recognize that you’re completing goals which will increase dopamine.

9. Supplementation.

These are the supplements that can boost dopamine levels:

Curcumin – found in turmeric

Ginkgo Biloba

Acetl-l-tyrosine

L-theanine, which is found in green tea.

10. Meditation.

This works differently compared to exercise. It will make you more calm and relaxed, which will enable you to reduce stress.

Source:truthinsideofyou.org