The World’s Most Powerful People 2015.


Forget about the 1%. The men and women who are featured on Forbes’ annual ranking of the World’s Most Powerful People are the 0.00000001% –the global elite whose actions move the planet. These heads of state, financiers, philanthropists and entrepreneurs truly run the world.

To compile the list, we considered hundreds of candidates from various walks of life all around the globe, and measured their power along four dimensions. First, we asked whether the candidate has power over lots of people. Pope Francis, ranked #4 on our list, is the spiritual leader of more than a billion Catholics. Doug McMillon (#32), CEO ofWal-Mart Stores WMT +0.00%, employs 2.2 million workers.

Next we assessed the financial resources controlled by each person. Are they relatively large compared to their peers? For heads of state we used GDP, while for CEOs, we looked at measures like their company’s assets and revenues. When candidates have a high personal net worth, like the world’s richest man, Bill Gates (#6), we also took that into consideration. In certain instances, like the King of Saudi Arabia, Salman bin Abdulaziz Al Saud (#14), we considered other valuable resources at the candidate’s disposal –like 20% of the world’s known oil reserves.

Then we determined if the candidate is powerful in multiple spheres. There are only 73 slots on our list – one for every 100 million people on the planet – so being powerful in just one area is often not enough. Our picks project their influence in myriad ways: Elon Musk (#38) has power in the auto business through Tesla Motors, in the aerospace industry through SpaceX, because he’s a billionaire, and because he’s a highly respected tech visionary.

Lastly, we made sure that the candidates actively used their power. North Korean dictator Kim Jong-un (#46) has near absolute control over the lives of the 25 million people who live in his country, and is known to punish dissent with death.

To calculate the final rankings, a panel of Forbes editors ranked all of our candidates in each of these four dimensions of power, and those individual rankings were averaged into a composite score. Only the top 74 people (Brothers Charles and David Koch share the #29 spot) made the final cut.

View the full list of The World’s Most Powerful People

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Russian President Vladimir Putin emerged as the world’s most powerful person for the third year running. Putin continues to prove he’s one of the few men in the world powerful enough to do what he wants –and get away with it. International sanctions set in place after he seized Crimea and waged war-by-proxy in Ukraine have kneecapped the Ruble and driven Russia into deepening recession, but haven’t hurt Putin one bit: In June his approval ratings reached an all-time high of 89%. In October, he bombed ISIS forces in Syria and then met face-to-face with President Assad, making the U.S and NATO look weak in the region, and helping rebuild Russian influence abroad.

The second most powerful person in the world also happens to be the most powerful woman: Angela Merkel, the chancellor of Germany, jumps up from #5 last year to take the runner-up spot on the list. Merkel is the backbone of the 28-member European Union, and her decisive actions dealing with the Syrian refugee problem and the Greek credit crisis helped bump her up the list.

U.S. President Barack Obama fell one spot on this year’s list to #3. There’s no doubt that the United States remains the world’s greatest economic, cultural, diplomatic, technological and military power. But as Obama enters the final year of his presidency, it’s clear his influence is shrinking, and it’s a bigger struggle than ever to get things done. At home, his approval ratings are perpetually stuck under 50%; abroad, he’s outshined by Merkel in Europe, and outmaneuvered by Putin in the Middle East.

New members of the list include Dell CEO Michael Dell (#59); China’s richest man,Wang Jianlin (#68); newly elected Canadian Prime Minister Justin Trudeau (#69); billionaire activist investor Carl Icahn (#70); and U.S. Presidential candidate Donald Trump (#72).

Any ranking of the world’s most powerful people is going to be subjective, so we don’t pretend ours is definitive. It’s meant to be the beginning of a conversation, not the final word. So tell us what you think: Is the CEO of Amazon more powerful than the CEO of Apple or Facebook? Is ex-president Bill Clinton (#64) really more powerful than the current Prime Minister of Canada? Does someone like Donald Trump belong on the list at all? Who did we miss? What did we get wrong? Join the conversation by commenting below.

NASA Researchers Disclose the Truth About Time Travel & Dimensional Portals


Stargate Dimensional Portal

Physics needs some new running shoes, or at least an updated framework in which to understand itself so that it won’t be running in circles trying to get to Saturn or a distant star in a galaxy far, far away. That’s the sentiment among those in elevated levels of government as well as individuals who understand higher consciousness. Why? There are places all over the Universe we can travel to in an instant, using energetic portals in space, and the use of our consciousness.

The proof is indeed mounting that there are portals to other worlds. Though the documentation is still ‘sketchy’ to describe how this is done in black and white, there is a trail there for those who want to follow it.

There are literary hints as well as soft evidence and testimony of numerous whistleblowers. ConsiderAlice’s rabbit hole. The tornado in the Wizard of Oz. Platform 9 ¾ in Harry Potter. The ‘Gate of Hell’ in Dante’s Inferno. These are just a few.

Ancients knew of portals not just to other Star Systems, but also to the inner earth, using stones, crystals, pyramids, and other structures aligned with the ley lines of this planet.

Within this framework we can look at the work of a NASA researcher who has revealed that there are portals to other dimensions that open and close every day. They are found within the earth’s magnetic field, and they are in a direct line to the sun’s atmosphere 93 million miles away.

Though NASA hasn’t labeled them as portals, and instead calls them Boom Tubes, electron diffusion regions or ‘X’ points, the process of magnetic resonance allows them to exist. This means that an extraordinary’ opening in space or time’ does exist, and NASA has known about them for an undefined duration. These ‘short-cuts’ are talked about in science fiction, and often dismissed by ‘real’ scientists.

Jack Scudder, a NASA plasma physicist from the University of Iowa, refers to X-points as:

Places where the magnetic field of Earth connects to the magnetic field of the Sun”These portals can be elusive, however, so if one were to imagine utilizing them for space travel, they would have to be an expert in space geography and mathematics to time them correctly.

Or, one could simply speak to the whistleblowers in the US government. Some claim that the military industrial complex has had the ability time travel through stargate portals for over 40 years. Andrew D. Basiago is a former participant in DARPA Project Pegasus (1968-72) who claims that the military developed Tesla-based quantum teleportation and time travel in the time space hologram, initiating the U.S. program of time-space Chrononauts. Basiago claims the military has been using portals since the 1970s. For more than 10 years, Basiago has been trying to tell the general public that portal-based time travel is not something from a sci-fi movie, but a present reality.

Basiago not only talks about time travel to more distant places, but claims the CIA has a Mars-jump-room program which allowed our military to build bases on Mars. He says that though he has worked with some of the leading quantum physicists, the information that he discloses is considered heretical by mainstream physicists, and the military as well.

Basiago states he participated in two ‘secret’ military programs. He says he was one of the many American children chosen to participate in time travel experiments. His accounts of what he experienced are measured with logic and it is difficult to discount what he says as pure fantasy. It is also, of course, in the best interest of the US military to keep these technologies secret, since they can be weaponized. This is no secret, since Rumsfeld has admitted that one of the boons of research done within Project Pegasus is the ability to use teleportation to deliver troops to the appropriate place on the battlefield.

So how does this happen?

This is a similar question that was attempted in the movie Contact staring Jodie Foster. The real life astronomer and ET chaser that inspired her character is Dr. Jill Tarter. She has stated, when asked what got her interested in the search for life beyond this planet:

The Cyclops Report from 1971 — written by Barney Oliver and John Billingham — was the result of a series of summer studies at NASA Ames and Stanford. In reading that workshop report, I was impressed by the notion that after millennia of asking priests and philosophers what to believe about life beyond Earth, the middle of the 20th century presented us with some tools that permitted scientists and engineers to do experiments to try to find the answer. Telescopes, rather than belief systems, could potentially show us what is, rather than what others said we should believe. I realized that I was in the right place, at the right time, with the right skills (undergrad degree in engineering physics and Ph.D in astronomy) to join this exploration. I got hooked, and have stayed hooked all these years.”

We’re all hooked. That’s because if alien life exists, then surely there are forms of life that are way more advanced (both consciously and technologically) than we are, and these forms of life most assuredly can travel ‘in the blink of an eye’ without necessarily having to overcome gravity, the limitations of rocket fuel, or even the scarcity of physical materials which could not easily withstand the heat of the sun or the extreme cold of deep space.

If our minds could simply create the energy we need to travel more than 9 billion light years before we’re 9 billion years old, then space travel would become commonplace. Perhaps even our highly developed intuition would understand that strange math that allows thought to travel as a wave and to form more cogently in material form on the other side of Pluto.

Nikola Tesla alluded to something of this nature. He developed a ‘teleportation machine’ which formed a ‘shimmering curtain.’

“Radiant energy is a form of energy that Tesla discovered that is latent and pervasive in the universe and has among its properties the capacity to bend time-space.” – Andrew Basiago

Passing through this curtain of energy, Basiago would enter a “vortal tunnel” that would send him to his destination. The other teleportation devices included a “plasma confinement chamber” in New Jersey and a “jump room” in El Segundo, California. There was also some kind of “holographic technology,” which allowed them to travel “both physically and virtually.”

They weren’t always safe, though. One of Basiago’s cohorts, Alfred Webre, recalls one instance in which a child returned from his temporal voyage before his legs. As he puts it, “He was writhing in pain with just stumps where his legs had been.” These bugs, according toWebre, have been ironed out in the 40 or so years since the experiments began.

If our consciousness just needs to catch up to the materialization of matter, anything is possible, but we’ve got plenty of work to do before packing a bag for MACS0647-JD a mere 13.3 billion light years away. I’d hate to forget my wallet in Sacramento while my energy was being catapulted to this distant galaxy, let alone my legs. New shoes indeed.

Heat-triggered ‘grenades’ hit cancer .


Liposomes

Scientists have designed microscopic “grenades” that can explode their cancer-killing payload in tumours.

The team will present its findings at the National Cancer Research Institute conference next week.

They plan to use liposomes – tiny bubbles of fat which carry materials round the body – to release toxic drugs when their temperature is raised.

The “grenades” are intended to avoid side-effects by ensuring the drugs target only the tumour.

Experts said such technology, which has been effective in animal experiments, was the “holy grail of nanomedicine”.

Cancer scientists are trying to harness the transporting abilities of these fatty spheres by getting them to carry toxic drugs to tumours.

“The difficulty is, how do you release them when they reach their target?” Prof Kostas Kostarelos, from the University of Manchester, told the BBC News website.

The Nanomedicine Lab in Manchester has designed liposomes that are water-tight at normal body temperature. But when the temperature increases to 42C they become leaky.

“The challenge for us is to try to develop liposomes in such a way that they will be very stable at 37C and not leak any cancer drug molecules and then abruptly release them at 42C,” Prof Kostarelos added.

Warming

He suggests heat pads could be used to warm tumours on the body surface such as skin, head or neck cancers.

Grenade

Probes can heat tumours inside the body, and there is also discussion about using ultra sound to warm tumours.

In early tests on mice with melanoma there was “greater uptake” of drugs in tumours using the thermal grenades. And that resulted in a “moderate improvement” in survival rates.

Prof Kostarelos said similar techniques were being trialled in patients and this “is not a fantasy.”

Prof Charles Swanton, the chairman of the conference, said targeted liposomes were a “holy grail of nanomedicine”.

He added: “These studies demonstrate for the first time how they can be built to include a temperature control, which could open up a range of new treatment avenues.

“This is still early work but these liposomes could be an effective way of targeting treatment towards cancer cells while leaving healthy cells unharmed.”

In new study, HIV prevention pill Truvada is startlingly 100 percent effective – The Washington Post


As far as emotions go, AIDS researchers tend to be a staid bunch who look skeptically at every new finding. But the results of a study released this week on an HIV prevention drug have many cheering.

The study conducted at Kaiser Permanente in San Francisco involved more than 600 high-risk individuals, most of whom were men who have sex with men. These individuals were healthy at the time of enrollment and were put on a daily regimen of a blue pill called Truvada as a pre-exposure prophylaxis (PrEP).

Lead author Jonathan Volk, a physician and epidemiologist at Kaiser Permanente San Francisco Medical Center, described the study as “the first to extend the understanding of the use of PrEP in a real-world setting and suggests that the treatment may prevent new HIV infections even in a high-risk setting.”


Bottles of antiretroviral drug Truvada are displayed at Jack’s Pharmacy on November 2010 in San Anselmo, California. (Photo Illustration by Justin Sullivan/Getty Images)
The Centers for Disease Control and Prevention says that PrEP has been shown to reduce the risk of HIV infection by up to 92 percent when taken consistently but is much less effective when taken inconsistently. In one key study, called PROUD that included men who have sex with men in Britain, the risk was reduced by 86 percent.

In this study, 100 percent of the participants remained HIV-free. That’s right, not a single person in the study, published in Clinical Infectious Diseases, became infected while on the drug during the study period that included 2.5 years of observation.

“Tremendously good news,” University of California-San Francisco researchers Kimberly A. Koester and Robert M. Grant (one of Time’s most influential people of 2012 for his work in AIDS) said of the results in a commentary accompanying the publication of the study.

Not long after the Food and Drug Administration first approved the drug for preventive HIV use in 2012, the Los Angeles-based AIDS Healthcare Foundation derided it as a “party drug” and warned that high-risk individuals would use it instead of condoms — raising the risk of transmission of other sexually transmitted diseases. #Truvadawhore went viral. But as more studies have come out showing how well it appears to protect against HIV, many of those critics appear to be turning around.
Koester and Grant emphasized that despite the promising findings in the Kaiser study many questions still remain, a number of them practical in nature.

“What proportion of the population vulnerable to HIV will take a pill a day to prevent it? How will costs of the medication and clinic visits be paid for?” they asked. “Assuming people are willing to use PrEP and can access PrEP, will they take the medication as directed? Will uptake and use be higher or lower among those at higher risk? Will people place themselves at higher risk or HIV and sexually transmitted infections (STIs) as a consequence of using PrEP?”

The pair said it wasn’t clear from the study if the reported rate of sexually transmitted infections in the study is an increase or not and that further investigation is needed. They recommended that Truvada be combined with a parallel plan to prevent other STIs which may include the use of condoms, more frequent testing and discussions with prospective partners.

There are several dozen other ongoing clinical trials worldwide using Truvada in different populations. In South Africa, for instance, National Institutes of Health-funded researchers are looking at its use in heterosexual adolescent men and women ages 15 to 19 and in Australia the government is looking at people in relationships with HIV-negative partners. The issues they are hoping to find out more about include the factors that can influence an individual’s compliance with taking the pills regularly, how effective the pill can be when it’s not taken regularly but before and after sex, and how to integrate education about Truvada into regular clinic services.

‘JEDI’ technology awakens new understanding of how immune system works


T cell
3D rendering of a T cell. 

When it comes to fending off disease and helping prevent people from falling ill, the body’s immune system—armed with T-cells that help eliminate cancer cells, virus-infected cells and more—is second to none. But exactly how the immune system works remains, in many ways, a mystery, as there are numerous cell types whose functions and interactions with our immune systems have not been well understood. Now, a team of scientists at the Icahn School of Medicine at Mount Sinai have developed the Just EGFP Death-Inducing T-cell, or JEDI T-cells, which enable the visualization of T-cell antigens, allowing researchers to study T-cell interactions with different cell types, model disease states, and finally determine the functions of otherwise poorly characterized cell populations.

The article was first published online in Nature Biotechnology.

“JEDI T- provide an unprecedented technology to study, model and visualize immune responses and immunotherapies in ways that were never before possible, and this has the potential to revolutionize immunology research,” said Brian D. Brown, BSc, PhD, Associate Professor of Genetics and Genomics Sciences at the Icahn School of Medicine at Mount Sinai, and senior author of the paper. “Immunotherapy is considered one of the most important breakthroughs in cancer care in decades, but there is more research needed to improve its success in the clinic. The JEDI technology will be integral to this effort, as well as helping to advance other area of drug development.”

Enhanced green fluorescent protein, or EGFP, was first discovered in jellyfish and is what gives these sea creatures their bright luminescence. In 1994, scientists first realized that putting the EGFP gene into cells made them glow green, making it possible to easily visualize them: ever since, scientists have generated thousands of living systems with EGFP, including EGFP-expressing viruses and EGFP-expressing .

The JEDI T-cells developed by Dr. Brown and his team at Mount Sinai enable researchers to study T-cells, the assassins of the immune system, as they interact with and kill any cell in the body, including pathogen-infected cells and even tumor cells. This is important because it makes it possible to model almost any autoimmune disease, evaluate new drug therapies, and even identify novel targets in the emerging area of cancer immunotherapies.

Using the JEDI technology, Mount Sinai researchers uncovered evidence that can find cells in the brain expressing their target antigen, even in non-infected states, which provides evidence of an immune surveillance pathway within the body’s central nervous system. This discovery has relevant implications for understanding neuroinflammation and even brain malignancies such as glioblastoma.

“In a galaxy far, far away, the Jedi knights defeated the dark side,” said Judith Agudo, PhD, Postdoctoral Fellow at the Icahn School of Medicine at Mount Sinai and first author of the study. “We believe the JEDI T-cells will help us win the fight against cancer, autoimmunity, and infectious disease.”

Just one steak a week can increase risk of bowel cancer, study finds


Scientists warn that just two portions a week increases the risk by almost a fifth

Eating a lot of red and processed meat probably increases your risk of bowel (colorectal) cancer

Eating just one steak a week increases the risk of bowel cancer by more than two-fifths, it has been claimed.

Scientists from Oxford University said that eating four portions of red meat could make you 42 per cent more likely to develop the disease.

And just two portions a week increased the risk by almost a fifth, they said.

Just last week, the World Health Organisation warned that bacon, ham and sausages ranked alongside cigarettes as a major cause of cancer.

A report said each 50g of processed meat a day – the equivalent of one sausage, or less than two slices of bacon – increased the chance of developing bowel cancer by 18 per cent.

In the latest study, Prof Tim Key and Dr Kathryn Bradbury looked at the records of 500,008 middle-aged British men and women aged 40 to 69, tracking their meat consumption for a four year period, according to the Daily Mail.

Over that time, 1,503 of the participants developed bowel cancer.

The study found that those who had had eaten red or processed meat four times a week were 42 per cent more at risk than those who had it once or not at all.

And those who ate it at least twice a week were 18 per cent more at risk compared with vegetarians.

Professor Key, who is due to present the findings at the National Cancer Research Institute conference in Liverpool on Tuesday, said: “People need to be aware of the risks and make modest changes if necessary.

“Eating things other than meat seems to be the sensible approach. So eating plant-based proteins such as beans, chicken or fish.”

The scientists based their analysis on average portion sizes, which equate to two rashers of bacon, two slices of ham or one sausage.

But a quarter pounder burger is 200g – nearly three times this level – while a 10oz steak from a restaurant is equivalent to 284g, or more than four portions.

The study also found that eating large amounts of fibre did not significantly lower the risk of developing bowel cancer.

Bowel cancer is the second biggest cancer killer in the UK, leading to 16,000 deaths a year.

Mark Flannagan, chief executive of Beating Bowel Cancer, said: “We must not underestimate the importance of diet in reducing your risk of bowel cancer.

“The evidence suggests there is a strong link between red and processed meat and bowel cancer, so we recommend eating both in moderation.”

Current NHS advice is to limit intake of all meats to 70g a day, but there is no specific recommended limit for cured and processed meats.

The average person in the UK has 2.5oz (70g) meat a day 3oz (88g) among men, 2oz (52g) among women) but one in three people have more than 3.5oz (100g) a day, research suggests.

The new advice from WHO suggests 50g of processed meat is enough to significantly raise bowel cancer risk, by 18 per cent.

One of the grandest structures ever built could be reborn in Greece


Until an earthquake in 226 BCE knocked it down, the Colossus of Rhodes, a 30-metre-high iron and bronze statue of the Greek god Helios, sat near the harbour of Rhodes, Greece, for 54 years.

Now, a plan put forth by a small team of scientists seeks to rebuild the ancient statue and boost tourism and local jobs in the process.

colossusrhodes1A rendering of the 400-foot Colossus of Rhodes reboot. 

The plan calls for a new statue that’s way taller than the ancient one. At 122 metres tall, the new Helios would be nearly four times the height of the original. The proposal also includes an interior library, museum, cultural centre, exhibition hall, and, of course, a crowning lighthouse that’s visible for 56 kilometres.

One obvious change to the new structure is that it would use modern construction techniques and technology to make it earthquake-proof. The exterior would be completely covered in golden solar panels, making it entirely self-sufficient, which is appropriate for the Greek god of the sun.

colossusrhodes2A museum inside the statue would display ancient Greek treasures currently stored away. 

It’s estimated that the project can be completed in three to four years at a cost of 240 to 260 millions euros (US$264 to US$286 million). Funding is expected to come from cultural institutions and international crowdfunding.

In addition to renewing and extending Greece’s tourism season, the statue’s construction would bring much-needed jobs. Whether or not this will all come together depends on how much support and money the team behind the plan can raise. No construction dates have been released.

colossusrhodes3A view of the statue’s lighthouse, which would glow for up to 35 miles. 

colossusrhodes4A museum and library are among the interior plans for the statue.

colossusrhodes5This time, the statue will be earthquake-proof. 

colossusrhodes6A solar panel skin will make the structure entirely self-sustaining.