Abnormal IVF embryos can now be predicted within 30 hours of development .


The chromosomal abnormalities that affect at least half of the human embryos created for in vitro fertilisation (IVF) can now be predicted within the first 30 hours of development at the cell-1 stage – days before they need to be transferred into a woman’s body.

The discovery could help improve the odds of an IVF embryo developing into a pregnancy. Right now, the global percentage for a successful pregnancy from an IVF embryo sits between 30 and 35 percent. The reason such low odds exist is that between 50 and 80 percent of all embryos created for IVF end up developing a severe chromosomal abnormality that can dramatically increase their chances of being miscarried, and but we have no way of knowing which ones before they need to be implanted.

The US-based team has figured out how to tell whether an embryo will develop normally within the first three days after conception. This means that abnormalities can be detected at the earliest stage of human development, which will allow doctors to make a more informed choice when selecting embryos for implantation, and spend less time culturing embryos that were never going to make it.

Prior to the discovery, abnormalities could only be detected at day five or six, which means these embryos have to be cultured and implanted before being identified and miscarried. And that’s a horrible experience for the mother, and a waste of resources for the doctors, who could have been cultivating healthier embryos for her.

“A failed IVF attempt takes an emotional toll on a woman who is anticipating a pregnancy as well as a financial toll on families, with a single IVF treatment costing thousands and thousands of dollars per cycle,” one of the team, Shawn L. Chavez from Stanford University, said in a press release. “Our findings also bring hope to couples who are struggling to start a family and wish to avoid the selection and transfer of embryos with unknown or poor potential for implantation.”

The discovery builds on a study by Chavez and his team back in 2012, in which they found that by timing the first three mitotic cellular divisions in embryonic development while checking whether the process of cellular fragmentation is happening, they can figure out which embryos aren’t developing right. The team describes cellular fragmentation as “a phenomenon of unknown origins that is thought to be acellular debris and affects approximately 50 percent or more of IVF embryos”.

The current study, which was published in Nature Communications, tested this out on 117 human zygotes  from 19 couples, with an average maternal age of 33.7 years. They non-invasively examined the embryos at a single-cell level and compared their chromosomal structure with the make-up of 12 developmentally relevant genes that are activated prior to the first cell division. Using a computer model, they could predict whether the embryo will be chromosomally normal or abnormal as it develops.

“With assisted reproduction at an all-time high, we want to help more families achieve successful pregnancies,” said Chavez. “IVF has helped countless women all over the world, and we now have the technology and research to improve a couple’s chances of having a biological child of their own. This discovery can potentially increase those chances.”

While it’s not clear at this stage how this will actually affect IVF treatments, the researchers are keen to have their research continued by other teams to figure out even stronger markers for abnormalities.

The Heart’s Intuitive Intelligence: Scientific Proof Of Intuition


We all know the difference between good vibes and bad vibes, but what is really happening at a scientific level when we talk about “vibes”?

Or what about when we know someone is a bad person and can feel it in our gut, only to later find out that they are abusive and manipulative?  While there is an energetic and spiritual side to this question, there is also a hard scientific explanation of what is occurring when we tap into the vibes of other people.   With the development of new scientific instruments, intuition is now something being studied using the scientific method.

The electromagnetic field of the heart

The heart generates a powerful and measurable electromagnetic field.  Magnetocardiography is the science of measure the field that is produced by the electrical activity within the heart.  It’s mainstream scientific knowledge that the resonant frequencies of the field of your heart interacts with the fields of others around you.  This effect is super strong within the first several feet in particular, but has been reported to be measured even at a distance of hundreds of meters.

Most of us know that the heart holds an energy system of its own and is one of the 7 main chakras within our energy field, and that our heart centers can interact with the heart centers of others.  But it turns that it’s more than just an energy center for emotions, spiritual health, or even nervous system activity.  The heart almost acts as a second mind with its own sense of awareness.

The Institute of Heartmath is an organization that focuses on the science of the heart and its relationship to the brain, nervous system, and the energy of the planet.  Their studies have shown time and time again that the heart is a “little brain” and has an intuitive intelligence of it’s own independent of the mind.

“We observed that the heart was acting as though it had a mind of its own and was profoundly influencing the way we perceive and respond to the world. In essence, it appeared that the heart was affecting intelligence and awareness.”

The studies proving the heart’s intuitive intelligence

 

 

 

 

 

In this study, 26 participants were shown a series of 45 pictures.  30 of the pictures were neutral, and 15 of them were emotionally arousing.  The participants were hooked up to an electrocardiogram to measure cardiac accelerations and decelerations, and an electroencephalogram to measure heart-beat evoked “potentials” on the surface on the skin.  What the found was incredible.

A significantly greater heart rate deceleration occurred prior to future emotional stimuli compared to calm stimuli, and there was a significant difference in the refraction period within cardiac cycles for the emotional versus the calm.  Both the heart and the brain were responding to the emotionally arousing photos prior to them even being seen by the person in linear time, but the heart was receiving the intuitive information prior to the brain.

The also found that there was a large difference in intuitive intelligence between males and females, and the females pick up on intuitive information more often and at a quicker rate than men did.  So the spiritual concept of females being more in touch with their intuitive and emotions is not just New Age philosophy. It’s now scientifically proven that intuition is real, the heart plays a more important role in intuitive information than the brain, and that females are more heart-centered.

As they concluded in the original study found here:

Once the prestimulus information is received in the psychophysiologic systems, it appears to be processed in the same way as conventional sensory input. This study presents compelling evidence that the body’s perceptual apparatus is continuously scanning the future.

Watch the video. URL:https://youtu.be/QdneZ4fIIHE

Taking Gym Steroids Can Affect Memory, Health


People using steroids to boost muscle growth and sporting performance are far more likely to experience issues with their memory, a new study has claimed.

Dr Tom Heffernan from Northumbria University’s Department of Psychology aimed to examine whether the long-term use of high doses of anabolic-androgenic steroids within a sporting context might affect everyday memory.

He assessed almost 100 males aged 18-30 who were regular gym users. Half of the group used steroids and half did not.

The results showed that those using steroids had significantly more deficits in their prospective and retrospective memory functioning, as well as their mental executive function, compared to non-users.

Steroid users were 39 per cent more forgetting in terms of prospective memory – the process of remembering to do something you had planned to do in the future, such as remembering to pay a bill before it is due or to take medication at a certain time.

They were also 28 per cent more forgetting when recalling past memories or previous facts, known as retrospective memory, and demonstrated a 32 per cent difference in their mental executive function compared to non-users.

Executive functioning is a term used to describe a number of cognitive processes that help an individual to pay attention, coordinate information and plan and execute tasks.

A compromised executive function is likely to lead to confusion and poor planning, while reduced prospective memory ability leads to forgetfulness.

While a previous study from Harvard University found deficits in visuo-spatial memory in long-term steroid users, this is the first study to explore the impact that steroid use in a sporting context has on memory for everyday activities.

“The non-medical use of anabolic-androgenic steroid use came to the forefront in the 1960s when elite athletes and bodybuilders used the drugs to promote muscle growth and improve performance levels,” Heffernan said.

“Since the 1980s many millions of individuals worldwide have used such steroids in a sporting context, which has now become much more widespread within non-competitive recreational sports circles.

“Overall the health-related risks of long-term steroid use are fairly well documented but we know much less about what the everyday consequences of their use may be.

“Our findings suggest that long-term use of anabolic-androgenic steroids has a significant impact on an individual’s everyday memory and ability to remember,” said Heffernan.

Pfizer Vice President Blows The Whistle & Tells The Truth About The Pharmaceutical Industry


Screen Shot 2015-07-06 at 11.28.13 AM
Below is a clip taken from the “One More Girl” documentary, a film regarding the Gardasil vaccine, which was designed to prevent Human Papillomavirus. In it, Dr. Peter Rost, MD, a former vice president of one of the largest pharmaceutical companies in the world (Pfizer), shares the truth about the ties between the medical and pharmaceutical industry.

Rost is a former vice president of Pfizer, and a whistleblower of the entire pharmaceutical industry in general. He is the author of “The Whistleblower, Confessions of a Healthcare Hitman.” Considering his work experience, it would be an understatement to say that he is an insider expert on big pharma marketing.

Below are a couple of quotes from both a former and a current editor-in-chief of the two largest, and what are considered to be the most credible, medical journals in the world. It’s only fitting to include them into the article as they are directly related to what Dr. Rost hints at in the video.

“It is simply no longer possible to believe much of the clinical research that is published, or to rely on the judgment of trusted physicians or authoritative medical guidelines. I take no pleasure in this conclusion, which I reached slowly and reluctantly over my two decades as an editor of the New England Journal of Medicine.”  – Dr. Marcia Angell, a physician and longtime editor-in-chief of the New England Medical Journal (NEMJ) (source)

“The case against science is straightforward: much of the scientific literature, perhaps half, may simply be untrue. Afflicted by studies with small sample sizes, tiny effects, invalid exploratory analyses, and flagrant conflicts of interest, together with an obsession for pursuing fashionable trends of dubious importance, science has taken a turn towards darkness.”  – Dr. Richard Horton, the current editor-in-chief of the Lancet – considered to be one of the most well respected peer-reviewed medical journals in the world. (source)

It’s Time To Re-Think Current Medical Research & See The Bigger Picture

In 2005 Dr. John P.A. Ioannidis, currently a professor in disease prevention at Stanford University, published the most widely accessed article in the history of the Public Library of Science (PLoS) entitled Why Most Published Research Findings Are False. In the report he states:

“There is increasing concern that most current published research findings are false.”

We now have a large amount of evidence, and statements from experts that come directly from the field, which paint a very concerning picture. The science used to educate doctors and develop medicine is flawed. We are only ever exposed to studies that have been sponsored by big pharmaceutical companies, but these studies are not designed to take the long view. They are not designed to detect problems that can occur years or even decades after a treatment, or examine the risks of taking a drug for long periods of time. Nobody ever seems to mention or acknowledge the many studies which clearly show significant risk associated with many of the products that pharmaceutical companies are manufacturing to help fight disease.

What is even more concerning is the general population’s lack of awareness when it comes to these facts. This issue is definitely not going to be addressed in the mainstream news, and despite plenty of evidence to support it, some people will refuse to even look at or acknowledge that it exists. This is a big problem, our world is changing and we must keep an open mind and be open to new possibilities regarding the nature of our world. It’s 2015, and as we keep moving forward there will be more information coming out that challenges the deeply held, engrained belief systems of many. It’s okay to look at information that goes against what you believe, in fact, it’s needed if we are going to move forward and create a better world for ourselves.

You would think the statements above the video, from longtime editors of such major, peer-reviewed scientific journals (apparently, the best in the world) would at least get some mainstream attention.

When Dr. Rost was still working for Pfizer he had a couple of appearances in the mainstream media. Hereis an example of him speaking with the Wall Street Journal almost 10 years ago, before he blew the whistle.

This is why alternative media is important, especially in a time where more and more people are waking up to what is really happening on our planet.

It’s time to examine the research that’s being conducted all over the world, from experts (scientists) at various institutions, that is not sponsored by these giant, multinational “health” corporations – the independent literature. Brilliant work is being published regarding various drugs, cures, treatments, vaccines, and more.

watch the video. URL:https://youtu.be/TrCizlAOBAo

How to Heal your Eyesight Naturally


My eyesight has always been pretty good, but for a long time I did wear glasses. Several years ago I started practicing “healing my eyes” with some rather simple stuff that I was thinking about at the time. Relax your muscles around your eyes, close your eyes gently and look into the sun absorbing the light (also while relaxing the muscles), and carrying crystals that supposedly had a relationship to the quality of your eyesight. When I first stumbled upon this video I got super excited about it! The results that I’ve had have been noticeable to me, although as it has not been my primary focus, the results have waxed and waned. I’ve felt that when I spent a week or two putting conscious effort into it – I would see at least small results, if not somewhat like “jumps” in the quality of my sight. Upon watching the video, I found myself pleasantly surprised. This guy is a legitimate doctor, who has used a method from a “renegade optometrist” from about a hundred years ago who put together a solid formula for healing your eyes. The best part about it is that what he’s saying really resonates with me, and I think even though there’s a lot more to it, it sounds a lot like what I’ve been practicing. For example, as I wrote earlier when I wake up in the morning I like to go outside and just close my eyes gently and stare into the sun. It not only helps my eyes wake up, but my whole mind wakes up! Not to mention, my eyes lose their “morning grogginess” completely, and my eyesight seems to be really great, much better than had if I did not do it. Likewise, the whole “don’t squint” thing is another practice, and it totally makes sense! Like, if you’re whole face is squinting and stressed out all of the time, then that’s constricting the way your face and head receives energy – both with light through our eyes, energy in our 3rd eyes, or smells through our noses. And if there’s no more strain, then your brain, eyes, and facial muscles can all function with ease and clarity. Energy can flow smoothly, and it only makes sense that your eyes will naturally improve as well. For all of us with glasses, let’s give these tips a practice and see how we do!

How You Can Slow Down Time


This thing all things devours:
Birds, beasts, trees, flowers;
Gnaws iron, bites steel;
Grinds hard stones to meal;
Slays king, ruins town,
And beats high mountain down.”

– Gollum, The Hobbit

Time has long seemed to be one of humanity’s greatest foes, a mysterious force that we really only seem to notice when we are its victims. At the end of a vacation we might ask how time went by so fast. When stuck in traffic we wonder how it can move so slow. But it’s rare for us to reflect happily on its passage.

In the ancient Roman philosopher Seneca’s essay “On the Shortness of Life”, the first-century Stoic rebuts the oft-heard claim that life is too short: “It is not that we have a short time to live, but that we waste a lot of it. Life is long enough, and a sufficiently generous amount has been given to us for the highest achievements if it were all well invested.

But when it is wasted in heedless luxury and spent on no good activity, we are forced at last by death’s final constraint to realize that it has passed away before we knew it was passing… our lifetime extends amply if you manage it properly.” Seneca argues that we must watch how we spend our time the same way we tend to guard our money.

But what is it that he suggests we save our time for? The study of philosophy, an occupation which brings us out of time completely and allows us to converse with the greatest minds of old – this is what Seneca most valued. On the off chance you don’t share his enthusiasm, modern psychology offers another perspective.

Why does time pass so quickly?

Time Warped is a book by Claudia Hammond which explores the way our minds perceive time. To Hammond, the acceleration of time that we feel isn’t just an error, a trivial mark of our mental weakness. It is an essential aspect of the world of time in which we humans live. Time as we know it does not steadily progress along a linear path, it changes in pace as we look at it forwards and backwards, influenced by our memory and attention. To understand the human struggle with the passage of time we must understand it as a human struggle.

Why does time pass so quickly? Looked at closely you should be able to answer this for yourself. When you are engaged in an activity which you enjoy or which fully captures your attention, you may find that you’ve completely lost track of time and more of it has passed than you had thought. On the other hand, boredom slows it down. Regarding the larger scale of weeks and months, many researchers have found that time seems to have passed more quickly when we have had less new experiences. This explains why many feel that time passes faster as they grow older. The first couple decades of life are filled with new experiences as we sample what life has to offer. Looking back this time seems to have been so well packed with activity that we imagine it must have passed quite slowly. But as we get older and find the patterns most comfortable to us we often notice time speeding up in retrospect, as our memories are filled with less of those new stand-out events.

alarm-clock-living-room

How do we make time go slower?

Using this information, Hammond offers some suggestions for combating the ailments of time. If you wish to look back and feel that your time has been long and well-spent, actively fill it with new activities. But, she warns, you may find that the relaxing but less note-worthy preoccupations you appreciate are not so much worse. Alternatively, when faced with a block of bored time she suggests the obvious: Find something to keep your attention. She recommends giving the practice of mindfulness a try, closely observing the world around you.

In the book Hammond addresses a myriad of similar topics which share one interesting thing in common: When we look to battle the mysterious withering force of time, we never combat it directly. This is because time was never really fighting us. Our memories may make us fear that we are wasting away. Our boredom may drive us insane. But time looks on, simply serving as a marker to us, a mysterious but unthreatening experience composed of mental processes. You’ll have a hard time escaping it, maybe you’ll save yourself some trouble if you befriend it?

“A book no more contains reality than a clock contains time. A book may measure so-called reality as a clock measures so-called time; a book may create an illusion of reality as a clock creates an illusion of time; a book may be real, just as a clock is real (both more real, perhaps, than those ideas to which they allude); but let’s not kid ourselves – all a clock contains is wheels and springs and all a book contains is sentences.”

– Tom Robbins, Even Cowgirls Get the Blues

Can You Reduce Steroid Treatments for Sarcoidosis?


If you have sarcoidosis, your doctor may prescribe steroids at some point during your treatment. Specific types of steroids can treat the symptoms of this inflammatory condition, which often affects the lungs.

But steroids are not for everyone. Used long-term, steroids present a long list of potential side effects. That’s why doctors often look for “steroid-sparing” treatments to address sarcoidosis over time.

Below, Daniel Culver, DO, a leader in treating sarcoidosis, describes the concerns surrounding steroids, as well as treatment alternatives.

The risks of long-term steroid use

Sarcoidosis can affect any organ, but about 90 percent of cases involve the lungs, Dr. Culver says. Cases that involve the heart or central nervous system are less common but more often need treatment.

Most clinicians look to steroids as the first line of treatment. Steroids treat inflammation quickly and effectively. Prednisone is the mainstay, but some doctors also will use methylprednisolone intravenously.

However, chronic use of steroids comes with the risk of side effects. Common issues include mood or personality changes, obesity, diabetes, infection, osteoporosis, hypertension, cataracts, glaucoma, and thinning of the skin.

“Steroids cause obesity because it makes you more anabolic, so you tend to accumulate fat and eat more,” Dr. Culver notes, addressing a common concern. And they can affect diabetes by changing your glucose sensitivity. They can either make an existing case of diabetes worse or unmask a new case.

“Steroid-sparing” treatments

Because of concerns about steroids, doctors often look for alternatives. For example, Cleveland Clinic’s Sarcoidosis and Interstitial Lung Disease Program reports that it reduced average daily steroid dose for patients by more than 80 percent through use of steroid-sparing therapies.
Because of concerns about steroids, doctors often look for alternatives.
Choosing the right treatment depends on the organ involved or target of treatment, Dr. Culver says.

For severe sarcoidosis, doctors often use cytotoxic drugs like methotrexate, azathioprine, and leflunomide. These three drugs all target roughly the same organs, and seem to work approximately equally well, he says.

More recently, clinicians have started using drugs calledTNF (tumor necrosis factor) antagonists for patients who don’t respond to moderate-dose steroids or cytotoxic drugs. TNF antagonists seem especially effective for skin and neurologic issues, Dr. Culver says. Doctors may also prescribe anti-malarial medicines such as hydroxychloroquine for skin disease or calcium problems.

Of course, any drug comes with side effects. Patients on methotrexate have reported nausea, elevation of liver enzymes, suppression of blood counts, or fatigue. Azathioprine and leflunomide can cause diarrhea or cramping, as well as abnormalities of liver enzymes and blood counts.

“Most patients don’t experience those side effects, but those are some of the things I talk to patients about when I start them on these drugs,” Dr. Culver says.

In addition to these medications, new treatments are on the horizon. Several clinical trials are underway. And Acthar gel, a clinical drug first approved by the Food and Drug Administration in the 1950s for at least 20 to 30 different uses, is getting renewed attention for sarcoidosis.

What to ask your doctor

Not all sarcoidosis patients need treatment, Dr. Culver notes. For 50 to 75 percent of patients, the condition is likely to go away on its own.

If you do need treatment, talk to your doctor about what medications would be the best for you. Those may include steroids or other medications mentioned above, or you may be a good candidate for clinical trials.

Steroids will continue to have their place as a treatment. For patients who don’t require long-term treatment, steroids might be the most appropriate option, for example. “They work more quickly and they’re more reliable than most other medications,” Dr. Culver says.

Brain imaging shows how children inherit their parents’ anxiety — ScienceDaily


A study in an extended family of monkeys provides important insights into how the risk of developing anxiety and depression is passed from parents to children.The study shows how an over-active brain circuit involving three brain areas inherited from generation to generation may set the stage for developing anxiety and depressive disorders.

A prefrontal-limbic-midbrain circuit is responsible for the genetic transfer of an anxious temperament.

In rhesus monkey families — just as in their human cousins — anxious parents are more likely to have anxious offspring. And a new study in an extended family of monkeys provides important insights into how the risk of developing anxiety and depression is passed from parents to children.

The study from the Department of Psychiatry and the Health Emotions Research Institute at the University of Wisconsin-Madison shows how an over-active brain circuit involving three brain areas inherited from generation to generation may set the stage for developing anxiety and depressive disorders.

The study is being published this week in the Proceedings of the National Academy of Sciences (PNAS). It shows that elevated activity in this prefrontal- limbic -midbrain circuit is likely involved in mediating the in-born risk for extreme anxiety, anxious temperament that can be observed in early childhood.

“Over-activity of these three brain regions are inherited brain alterations that are directly linked to the later life risk to develop anxiety and depression,” says senior author Dr. Ned Kalin, chair of psychiatry at the UW School of Medicine and Public Health. “This is a big step in understanding the neural underpinnings of inherited anxiety and begins to give us more selective targets for treatment.”

Previous research by Kalin’s group has shown that anxious temperament is inherited, and explained the brain circuits involved. About half of children who show extreme anxiety go on to develop stress-related psychiatric disorders later in life.

Monkeys, like humans, can be temperamentally anxious and pass their anxiety-related genes on to the next generation.

By studying nearly 600 young rhesus monkeys from a large multi-generational family, Drs. Andrew Fox, Kalin, and colleagues found that about 35 percent of variation in anxiety-like tendencies is explained by family history.

To understand which brain regions are responsible for passing anxiety from generation to generation, the authors measured anxiety-related behavior with high-resolution functional and structural brain imaging. They exposed the young monkeys to a mildly threatening situation that a child would also encounter, exposure to a stranger who does not make eye contact with the monkey. During this encounter, they used imaging methods commonly used in humans (positron emission tomography, PET) to identify brain regions in which increased metabolism predicted each individual’s level of anxiety.

By closely examining how individual differences in brain function and anxiety-related behavior fall through the family tree, the authors identified brain systems responsible for the parent-to-child transmission of anxiety-related behavior. Using this “genetic correlation” approach, the authors found the neural circuit where metabolism and an early-life anxious temperament are likely to share the same genetic basis.

Interestingly, the brain circuit that was genetically correlated with individual differences in early-life anxiety involved three survival-related brain regions. These regions were located in the brain stem, the most primitive part of the brain; the amygdala, the limbic brain fear center; and the prefrontal cortex, which is responsible for higher-level reasoning and is fully developed only in humans and their primate cousins.

“Basically, we think that to a certain extent, anxiety can provide an evolutionary advantage because it helps an individual recognize and avoid danger, but when the circuits are over-active, it becomes a problem and can result in anxiety and depressive disorders,” Kalin explains.

Surprisingly, these studies found that it was the function of these brain structures — and not their size — that was responsible for the genetic transfer of an anxious temperament. Although the search for the genetic underpinnings of anxiety have thus far been elusive, this research helps explain how genes might affect brain function and lead to extreme childhood anxiety, which greatly increases the risk to develop anxiety and depressive disorders.

“Now that we know where to look, we can develop a better understanding of the molecular alterations that give rise to anxiety-related brain function,” Kalin says. “Our genes shape our brains to help make us who we are.”

Journal Reference:

  1. Andrew S. Fox, Jonathan A. Oler, Alexander J. Shackman, Steven E. Shelton, Muthuswamy Raveendran, D. Reese McKay, Alexander K. Converse, Andrew Alexander, Richard J. Davidson, John Blangero, Jeffrey Rogers, Ned H. Kalin. Intergenerational neural mediators of early-life anxious temperament. Proceedings of the National Academy of Sciences, 2015; 201508593 DOI: 10.1073/pnas.1508593112

Antioxidants May Preserve Memory in Early Alzheimer’s


Supplementation with omega-3 fatty acids and antioxidants could potentially benefit patients in the very early stages of Alzheimer’s disease.

Researchers recently studied the effects of this supplementation for 4 to 17 months in 12 patients with minor cognitive impairment (MCI), 2 patients with pre-MCI, and 7 patients diagnosed with Alzheimer’s.

These participants received omega-3 fatty acids and antioxidants in the form of a nutritional drink from Smartfish, which supported the study in part.

In an interview with Pharmacy Times, study author Milan Fiala, MD, a research professor at the University of California’s Department of Surgery, said omega-3 supplementation may benefit patients with MCI, but not those who have already developed Alzheimer’s dementia. Therefore, such supplementation would need an early start.

Patients with MCI and pre-MCI who received the supplementation saw an increase in phagocytosis of amyloid-beta, from 530 to 1306 mean fluorescence intensity units. Because such phagocytosis is ineffective in Alzheimer’s patients, targeting the clearance of amyloid-beta could benefit them, the researchers noted.

The Smartfish drink also contained resveratrol, and the combination of omega-3 and resveratrol showed evidence of improving the immune system against amyloid-beta in the brain, “probably by increasing its clearance from the brain by the immune system,” Dr. Fiala said.

While the omega-3 supplementation had “objective beneficial effects” on the immune system, which can prevent MCI, Dr. Fiala said some personal issues could interfere with the immune system response. She cited infections, surgeries, gastrointestinal intolerance, and medication noncompliance as potential interferences.

Omega-3 and antioxidant supplementation also increased resolvin D1 in macrophages in 80% of patients with MCI and pre-MCI. Resolvin D1 has also been shown to increase phagocytosis of amyloid-beta.

“Overall, the patients taking the drink seemed to preserve their memory better for up to 2 years than expected, based on previous studies,” Dr. Fiala concluded.

However, she pointed out that the study, which was published in The FASEB Journal, was small and not controlled by placebo.

Still, this study was the first to show significant immune and biochemical effects of supplementation in MCI patients, the researchers claimed.

“We’ve known for a long time that omega-3 fatty acids and some antioxidants can be beneficial to people with a wide range of health problems, as well as protective for healthy people. Now, we know that the effects of these supplements may extend to Alzheimer’s disease, as well,” said Gerald Weissmann, MD, Editor-in-Chief of The FASEB Journal in a press release. “Although these supplements are considered to be generally safe and are very easy to obtain, full-scale clinical trials are necessary to verify the findings of this research and to identify who might benefit the most.”