Kiwi pilot’s bike idea flies worldwide

A Kiwi adventure pilot who decided to strap mountain bikes under the wings of his plane is surprised to find himself suddenly world famous.

Mit Brereton, 27, hired a Manawatu engineering company to install bike racks under both wings of his 53-year-old Cessna six-seater when he bought a little Takaka-based company, Adventure Flights Golden Bay, three years ago.

A photo of the plane carrying bikes, posted on the company’s Facebook page two years ago, has suddenly gone viral.

Mr Brereton, who worked as a mineral exploration pilot before buying the company, believes his plane is the only one in the world that carries bikes on the outside. He flies cyclists in to the Heaphy Track during the track’s mountain biking season from May to September.

“I came up with the idea,” he said.

“The bikes are a bit big and bulky and they are difficult to carry. It’s only a six-seater and by the time you get five or six people in the plane there’s not a lot of room for the bikes.”

A Civil Aviation Authority spokesman said the bike racks had approval.

Stem cell-grown hair could help those with hair loss .

For the first time, researchers have been able to use pluripotent stem cells to generate cells that can grow new hair.

Hair growing on hairless mice thanks to induced pluripotent stem cells.Sanford-Burnham Medical Research Institute

It’s been theorised for years, but now human stem cells have resulted in hair growth for the very first time.

“We have developed a method using human pluripotent stem cells to create new cells capable of initiating human hair growth. The method is a marked improvement over current methods that rely on transplanting existing hair follicles from one part of the head to another,” said Alexey Terskikh, Ph.D., associate professor in the Development, Aging and Regeneration Program at Sanford-Burnham.”Our stem cell method provides an unlimited source of cells from the patient for transplantation and isn’t limited by the availability of existing hair follicles.”

The process started with human pluripotent embryonic stem cells — that is, stem cells that are capable of developing into any other cell — which were then developed into neural crest cells. These are cells that can develop into a variety of cells on the head, including brain cells, cartilage, bone and muscle cells.

From the neural crest cell point, the team coaxed the cells to grow into dermal papillae cells, the cells that nourish the skin and regulate follicle growth and formation. When transplanted — in the case of this study, into hairless mice — these cells flourish.

Another part of the study examined whether the same result could be achieved using dermal papillae cells taken from the scalps of adult humans. Outside the body, living in culture, these cells are not suitable for hair transplants, since they lost their ability to induce follicle formation. The number of hairs their produced was insignificant.

“In adults, dermal papilla cells cannot be readily amplified outside of the body and they quickly lose their hair-inducing properties,” said Terskikh. “We developed a protocol to drive human pluripotent stem cells to differentiate into dermal papilla cells and confirmed their ability to induce hair growth when transplanted into mice.”

The researchers say that their research represents the first step towards a cell-based treatment for hair loss, which affects 40 million men and 21 million women in the United States.

“Our next step is to transplant human dermal papilla cells derived from human pluripotent stem cells back into human subjects,” said Terskikh. “We are currently seeking partnerships to implement this final step.”

You can read the full study, “Derivation of Hair-Inducing Cell from Human Pluripotent Stem Cells”, online in the journal PLOS One.