From the desk of Zedie.
Nobody asks the nurse for the box or the insert when they get a flu shot. At least, I’ve never known anyone who said they did or do. Why not? We flip over food and beverage products all the time, to check for contaminants or stuff that we’re allergic to. Millions of Americans are getting injected every year with 100 times the mercury they’re worried about in fish, because they read about the salmon or tuna in some newspaper clip or saw a quick spot on the news.
Now remember, since most of the mercury in the food will be processed by your body with the food, you may only retain 10 percent of the toxic heavy metal. But when the nurse, who doesn’t offer you to look at the box or read the insert, jabs that needle into your upper arm and rubs it with a little cotton swab, while that nurse tries to help you avoid the flu, you’re actually getting something much MORE dangerous to your health (mainstream, “lame-stream” media cannot and will not talk about this).
Intramuscular injections contain 100 times the concentration of mercury you find in certain fish
If you’re a flu shot “frequenter” — meaning that you get one nearly every fall or winter, you are actually doing the opposite of what the flu “industry” (CDC) tells you on the insert and the box inside which the influenza vaccine comes. Yes, read it and you will know. Ask the nurse and have him/her leave the room while you review it. The flu shot warning tells you NOT to get the shot again if you’ve already had it. It doesn’t say how recently, or even whether that was when you were a child. It just flat out tells you not to get another one. So where does that put us with the whole vaccine schedule when you get 25 to 30 vaccines, including some flu shots, before the age of six? How much mercury are you getting and did you get, cumulatively, over the years? Is this why they warn you on the box and insert? (http://www.vaxchoicevt.com)
Have you gotten a FluLaval shot EVER before? Will you ever again? Natural health news enthusiasts are concerned for you. The ultimate health pioneer is looking out for you and is researching exactly which neurotoxins the “Medical-Industrial Complex” of the USA is pushing through those needles into the muscle tissue of kids, babies and pregnant women. Health Ranger Mike Adams uncovers this awful truth in the forensic food lab, where he tests everything from flu shots to Chicken McNuggets and Wheaties metal flakes! This is top-notch research being shared for the millions who follow Natural News and spread the word. Thanks, Mike, for all you do, digging into research that protects us from the hidden nightmares that Big Pharma besieges upon us.
You thought mercury-loaded fish were bad for you, try a flu shot!
Do you take the wrong kind of fish oil supplements? Threats from mercury are greater at lower levels than thought in the past. People go out to eat at restaurants and don’t even think twice about where the fish comes from. They eat tuna out of cans and can’t figure out their health problems, or the root causes. Then, they go and do something really dumb — they get a flu shot. How can something so popular be such a “common-senseless” thing to do? Maybe because the people getting them are still mentally challenged from the last one they got?
How would you like to “consume” 25,000 times as much mercury (level) as is the maximum allowed by the EPA for water? By injecting mercury into your blood directly, it also bypasses digestion, lung filtration and other natural defenses that your body would rather use to combat this heavy metal toxic nightmare. We are talking about 51 parts per million of inorganic mercury, but it’s supposed to help you fight off the flu, which your body should already be able to do just fine, if you weren’t eating GMOs daily and getting vaccines yearly!
Check out the free special report on The Hidden History of Medicine (disturbing facts) here:
Most potent juice recipe for erectile dysfunction
- alcohol use
- cocaine use
- being overweight or obese
- failing to control your diabetes
- lack of exercise
These habits can hinder proper blood circulation in our blood vessels.
Beet root contains high concentration of nitrites which helps open up the blood vessels in the body, increasing blood flow and oxygen specifically to places that are lacking oxygen.
This juice recipe for erectile dysfunction can be take 2 times a week, with this you are sure to kiss erectile dysfunction good bye.
Did you ever wonder how a cell phone might affect your brain? When you think about it, the use of cell phones is massively experimental, as we had no idea what kind of negative effects they might have on people when they were first introduced. Well now, decades after heavy use of cell phones, a study shows that brain tumor rates nearly triple after 25 years of cell phone use.
The Swedish study, published in the journal Pathophysiology, found that the longer someone talked on their phone — in terms of hours and years — the more likely they were to develop glioma, a deadly form of brain cancer.
The study found that, overall, people who used wireless phones for more than a year were at 70% greater risk of brain cancer as compared to those who used wireless phones for a year or less. Those who used wireless phones for more than 25 years were at a 300% greater risk of brain cancer than those who used wireless phones for a year or less.
Dr. Gabriel Zada, a neurosurgeon at the University of Southern California’s Keck School of Medicine who wasn’t involved in the study, said that the study provides more evidence that cell phones and brain cancer may be linked.
Indeed, the Swedish study came to similar conclusions as many other studies – that cell phone use increases brain cancer risk. Another study examining how cell phones might fuel brain cancer followed nearly 800,000 middle-aged women for seven years. In that time, there were 51,680 invasive cancers and 1,261 cancers of the central nervous system. But when analyzing the data and looking at the women who reported using cell phones for over ten years, a 10% increase in meningioma risk was discovered.
Here is the good news: even though the Swedish study mentioned above tripled the risk of developing glioma, the chances of someone being diagnosed with this type of brain tumor are extremely low. One study found that just more than 5 out of 100,000 Europeans (.005%) were diagnosed with a malignant brain tumor between 1995 and 2002. Tripling that rate puts the chances of developing glioma at .016%.
But even still, there are numerous ways cell phones could negatively affect your brain. So what can you do to prevent these potential negative effects? Whether you have the latest LTE technology or an old flip-phone, you can minimize your exposure to cell phone radiation by:
- Seldom holding the phone up to your head. This can be accomplished by either using the speaker option or using headphones with a microphone attached.
- Not sleeping with your phone next to you, and turning it off at night.
- Shutting it off while not in use.
- Look into, heavily research, and invest in radiation protection options for your phone.
- Placing your phone in ‘airplane’ mode if you cannot turn it off entirely.
Informing everyone of the dangers of cellphone use.
A study published in Cellular Physiology and Biochemistry titled, “Dietary Curcumin Ameliorates Aging-Related Cerebrovascular Dysfunction through the AMPK/Uncoupling Protein 2 Pathway,”[i] reveals the primary polyphenol in turmeric known as curcumin (which gives it its golden hue) may provide what the study authors describe as an “effective therapeutic strategy to reverse age-related cerebrovascular dysfunction.”
Age-related cerebrovascular dysfunction is occurring on an epidemic scale in Western countries and include, “stroke, cerebral amyloid angiopathy, cognitive decline and neurodegenerative diseases.” Presently, very few if any conventional medical interventions are capable of providing effective solutions, and none have been found to reverse underlying pathologies in conditions whose trajectories are generally characterized as ‘incurable.’ All the more reason why the new study holds so much promise in providing an evidence-based natural solution that is safe, effective, affordable and easily accessible as a familiar food ingredient.
- Curcumin promoted eNOS and AMPK phosphylation: Increasing nitric oxide (NO) bioavailability enables the inner lining of the blood vessels (endothelium) to fully dilate, reducing cardiovascular risk factors such as hypertension and associated damage to the arteries. Increased 5′-AMP activated protein kinase (AMPK) activity is also associated with improved age-related endothelial function.
- Curcumin upregulated mitochondrial uncoupling protein 2 (UCP2): UCP2 plays an important role in mitochondrial homeostasis and its optimal functionaing has been associated with increased lifespan.
- Curcumin reduced Reactive Oxygen Species (ROS) production: ROS reduction is associated with decreased oxidative stress and related cellular damage.
The authors summarized their findings as follows:
In summary, our findings provide the first evidence that chronic pharmacological AMPK/UCP2 pathway activation by curcumin treatment may be an effective therapeutic strategy to reverse age-related cerebrovascular dysfunction. Curcumin administration may represent a promising lifestyle intervention for preventing age-related cerebrovascular disturbances.
A Massive Body of Research On Curcumin’s Brain Protective Properties
GreenMedInfo.com houses a database of 1597 abstracts from the National Library of Medicine on thehealth value of turmeric and/or curcumin in over 600 health conditions. View them all here: turmeric health benefits. Of the 177 distinct beneficial physiological actions documented within this literature, 114 of them concern the spice’s neuroprotective properties. View them here: neuroprotective properties of turmeric.
While this latest study, and most of the research on our turmeric database is preclinical, there are reports of turmeric causing significant improvements in cerebrovascular dysfunction diseases such as Alzheimer’s. In a previous article titled, “Turmeric Produces ‘Remarkable’ Rocvery iin Alzheimer’s Patients,” we reported on the ability of turmeric to produce dramatic improvement in patients suffering from behavioral and psychological symptoms of dementia.
As we discussed in the article, other documented Anti-Alzheimer’s disease mechanisms of turmeric include:
- “Anti-inflammatory: Curcumin has been found to play a protective role against β-amyloid protein associated inflammation.
- Anti-oxidative: Curcumin may reduce damage via antioxidant properties.
- Anti-cytotoxic: Curcumin appears to protect against the cell-damaging effects of β-amyloid proteins. 
- Anti-amyloidogenic: Turmeric contains a variety of compounds (curcumin, tetrahydrocurcumin, demethoxycurcumin and bisdemethoxycurcumin) which may strike to the root pathological cause of Alzheimer’s disease by preventing β-amyloid protein formation.   
- Neurorestorative: Curcuminoids appear to rescue long-term potentiation (an indication of functional memory) impaired by amyloid peptide, and may reverse physiological damage by restoring distorted neurites and disrupting existing plaques.  
- Metal-chelating properties: Curcumin has a higher binding affinity for iron and copper rather than zinc, which may contribute to its protective effect in Alzheimer’s disease, as iron-mediated damage may play a pathological role. 
Turmeric, of course, is not the only natural substance that has been proven to have value in neurodegenerative conditions. For those looking for additional research on food and spice-based natural alternatives that are evidence based, here are additional substances that may be of value:
- Coconut Oil: This remarkable substance contains approximately 66% medium chain triglycerides by weight, and is capable of improving symptoms of cognitive decline in those suffering from dementia by increasing brain-boosing ketone bodies, and perhaps more remarkably,within only one dose, and within only two hours.
- Cocoa: A 2009 study found that cocoa procyanidins may protect against lipid peroxidation associated with neuronal cell death in a manner relevant to Alzheimer’s disease.
- Sage: A 2003 study found that sage extract has therapeutic value in patients with mild to moderate Alzheimer’s disease.
- Folic acid: While most of the positive research on this B vitamin has been performed on the semi-synthetic version, which may have unintended, adverse health effects, the ideal source for this B vitamin is foliage, i.e. green leafy vegetables, as only foods provide folate. Also, the entire B group of vitamins, especially including the homocysteine-modulating B6 and B12, may have the most value in Alzheimer’s disease prevention and treatment.
- Resveratrol: this compound is mainly found in the Western diet in grapes, wine, peanuts and chocolate. There are 16 articles on our website indicating it has anti-Alzheimer’s properties.
- Gingko biloba: is one of the few herbs proven to be at least as effective as the pharmaceutical drug Aricept in treating and improving symptoms of Alzheimer’s disease. 
- Melissa offinalis: this herb, also known as Lemon Balm, has been found to have therapeutic effect in patients with mild to moderate Alzheimer’s disease.
- Saffron: this herb compares favorably to the drug donepezil in the treatment of mild-to-moderate Alzheimer’s disease.
Updated November 2014
[i] Yunfei Pu, Hexuan Zhang, Peijian Wang, Yu Zhao, Qiang Li, Xing Wei, Yuanting Cui, Jing Sun, Qianhui Shang, Daoyan Liu, Zhiming Zhu. Dietary curcumin ameliorates aging-related cerebrovascular dysfunction through the AMPK/uncoupling protein 2 pathway. Cell Physiol Biochem. 2013 ;32(5):1167-77. Epub 2013 Nov 11. PMID: 24335167
Stress is affecting your brain much more than you think. Sure, you’ve experienced the distraction, forgetfulness, negativity or anxiety that comes from stressful situations, but did you know it’s also shrinking your brain? Hormones released in response to stress not only affect brain function, they also change the physical structure of your brain.
The stress hormone cortisol can kill, shrink, and stop the generation of new neurons in a portion of the brain called the hippocampus. (1) The hippocampus is critical for learning, memory and emotional regulation, as well as shutting off the stress response after a stressful event is over: all much-needed processes in both our professional and personal lives.
Chronic stress can also shrink the medial prefrontal cortex. (2) This negatively affects decision making, working memory, and control of impulsive behavior. Stress also has the ability to affect stem cells, inhibiting access to the prefrontal cortex, where we plan complex cognitive behavior and moderate social interaction. The result is a brain that is less capable of learning and memory, and more prone to anxiety and depression.
To make matters worse, these same stress hormones can increase the size and activity of a portion of the brain called the amygdala. (3) The amygdala is critical in the formation and storage of memories associated with highly emotional events. It pairs an event with a feeling, and this connection is stored away in our long-term memory so we can either avoid the event or seek it out in the future. The changes cortisol creates increase negative emotions such as fear, anxiety, and aggression.
These brain alterations can have significant consequences on the way we interact with others, our ability to learn, remember, make decisions and accomplish long-term goals. They also make it more difficult to successfully manage stressful situations in the future, leading to a vicious cycle.
Fortunately, we’ve discovered a very effective antidote to these negative effects: exercise. Exercise can help build a stress-resistant brain in addition to increasing cognitive function and brain size.
Exercise helps spur the release of a substance called brain-derived neurotrophic factor (BDNF), which helps in the development of healthy brain tissue and reverses the negative effects of stress. (4) Think of it as fertilizer for the brain. It keeps existing neurons vital and healthy and also encourages the growth of new ones. The more we exercise, the more BDNF we create, and the more neurons are generated, particularly in the hippocampus.
Exercise also releases human growth hormone (HGH), which is vital to the growth and development of all brain and body cells. HGH counteracts the natural cellular atrophy of aging and pumps up brain volume. (5) A single bout of sprinting for 30 seconds can generate a six-fold increase in HGH, with levels peaking two hours later. (6)
And thankfully you don’t have to do hour-long workouts to get many of these benefits. A recent analysis of 10 studies found that five-minute doses of exercise have the biggest effect on enhancing mood and combating stress. (7) Whenever you have a few minutes, do something that gets your heart rate up and/or challenges your muscles. It’s a positive, constructive way to deal with stress and can help keep you from losing your mind!
1) Sapolsky, Robert M. (1992) Stress, the Aging Brain, and the Mechanisms of Neuron Death. Cambridge, MA: The MIT Press.
2) Ansell, E., Rando, K., Tuit, K., Guarnaccia, J., Sinha, R. (2012) “Cumulative Adversity and Smaller Grey Matter Volume in Medial Prefrontal, Anterior Cingulate, and Insula Regions.” Biological Psychiatry. 72 (1): 57- 64.
3) Pittenger, C., Duman, R. (2008) “Stress, Depression, and Neuroplasticity: A Convergence of Mechanisms.” Neuropsychopharmacology Reviews. 33: 88- 109.
4) Cotman, Carl W., Berchtold, Nicole C. (2002) “Exercise: a Behavioral Intervention to Enhance Brain Health and Plasticity.” Trends in Neurosciences. 25(6): 295-301.
5) Ratey, John. (2008) Spark. New York: Little, Brown and Company. 256.
6) Ratey, John. (2008) Spark. New York: Little, Brown and Company. 256.
7) Barton, J., Pretty, J. (2010) “What is the Best Dose of Nature and Green Exercise for Improving Mental Health? A Multi-Study Analysis.” Environmental Science & Technology. 44: 3947-55.
Since the 1930s, scientists have been concerned about the health risks associated with electromagnetic fields (EMFs). These electromagnetic frequencies can cause dizziness, headaches, blood sugar imbalances, anxiety and, even, cancer. In fact, is was Samuel Milham, MD, MPH — author of Dirty Electricity — who first alerted the world to the frightening links between occupational exposure to electromagnetic fields, electromagnetic pollution and human disease.
Are you suffering with chronic disease? Obviously, a healthy diet and lifestyle are essential to reversing disease symptoms and completely healing the body. But, often overlooked in our immediate environment, the fact remains — wireless technology poses one of the biggest threats to human health. If you’re looking to resolve “unexplainable” health issues, don’t miss the next Natural News Talk Hour with Mike Adams and Jonathan Landsman.
Microwave (cell phone) radiation has been used as a secret weapon against humanity
This is not a joke. Dr. Barrie Trower, a former Royal Navy microwave weapons expert, reveals that there are 8,300 military papers proving that microwave frequencies — which can be found emanating from wireless mobile devices — cause severe neurological and physiological damage. In fact, from 1953 to 1975, a once-secret experiment bathed U.S. embassy employees (and their children) in Moscow with beams of low-levelmicrowave radiation — which caused an unusually high number of breast cancers, childhood leukemia and many other forms of cancer.
Keep in mind, the intensity of these microwave frequencies were similar to what we’re being exposed to with cell towers, microwave ovens, cell phones, Wi-Fi “hot spots,” wireless baby monitors and other mobile devices. And, although it’s hard to imagine, the American government knew about the dangers of microwave radiation and choose to keep it a secret — while they developed their own microwave weapons.
Today, operating above the law, we now know that government agencies can cause chronic fatigue, depression, suicidal tendencies plus a wide range of psychological and physical disorders by directing concentrated beams of microwave energy on “undesirables,” like government protestors. To learn more about how to protect your health — join Mike Adams and Jonathan Landsman for an informative program about the dangers of EMF pollution.
‘Smart’ meters represent one of the greatest threats to humanity
Dr. Dietrich Klinghardt, MD, PhD, founder of Klinghardt Academy, links the ever-increasing exposure to electromagnetic radiation (EMR) with the rapid rise in neurological illnesses like low-level depression, insomnia, chronic fatigue, numbness, tingling and “unexplainable” muscle aches and pains. In fact, Dr. Klinghardt believes that “smart” meters — which are being forced on homeowners as a way to “save energy” (yeah right) — are “the worst invention that we’ve followed in the last 2 years with absolutely devastating consequences.”
Simply put, if your local utility company wants to put a smart meter on your home, I urge you to refuse it (you have rights). To learn more about this particular topic, watch Take Back Your Power — an amazing documentary highlighting the health, privacy and security issues surrounding smart meters plus ways to protect your health.
Just to be clear, in the past 80 years, over 6,000 scientific papers have been published which show that electromagnetic fields — like those coming from smart meters — cause biological changes in human physiology. One notable study, from the University of Athens, showed that 143 proteins in the brain were altered, after exposure to mobile and cordless phone devices, including proteins linked to Alzheimer’s, brain tumors, stress and metabolic disorders.
Lead study author Adamantia Fragopoulou, MSc, PhD, said, “this study is anticipated to throw light in the understanding of such health effects like headaches, dizziness, sleep disorders, memory disorders, brain tumors, all of them related, to the function of the altered brain proteins.” To learn more about the science and dangers surrounding EMF pollution — read the “BioInitiative 2012 Report,” prepared by 29 authors from ten countries, ten holding medical degrees (MDs), 21 PhDs, and three MsC, MA or MPHs.
On the next Natural News Talk Hour, Mike Adams and Jonathan Landsman issue one of the biggest health alerts of the year. Don’t miss this program filled with lifesaving information and solutions.
Mike Adams, the “Health Ranger,” is an outspoken consumer health advocate, award-winning investigative journalist, internet activist and science lab director. He is the founder and editor of NaturalNews.com, the internet’s most-trafficked natural health news website and creator of CounterThink.com, FoodInvestigations.com, HealingFoodReference.com, HonestFoodGuide.org and several other websites covering natural health topics.
Adams is a prolific writer and has been called “the best health and natural products writer on the scene today.” (by Ronnie Cummins, founder, Organic Consumers Association) He has received accolades and testimonials from several key influencers in the natural health space, including Dr. Michael T. Murray and raw food pioneer David Wolfe.
Warning: Cell phones can trigger cancer cell growth. On May 31, 2011, the International Agency for Cancer Research — with the help of 31 world-class scientists from 14 countries — “classified radiofrequency electromagnetic fields as possibly carcinogenic to humans (Group 2B).” By the way, “Group 2B” carcinogenic agents also include DDT and lead. On the next Natural News Talk Hour, Mike Adams and Jonathan Landsman talk about the dangers of EMF pollution and real solutions.
Food for thought: there are cancers of the brain, blood, lymph nodes, lungs, bone, and every other bodily organ, part, or system imaginable. Why, then, do we never hear about heartcancer — could it be our hearts, long symbolized as the root of loving emotion, are somehow immune to the dreaded disease? Unfortunately, the reason no one ever talks about heart cancer is much more mundane. “We do have tumors that occur in the heart,” Dr. Jacqueline Barrientos, assistant professor, Hofstra North Shore-LIJ School of Medicine, told Medical Daily in an email, “but these are not as common, so you don’t hear about them.” Indeed, malignant heart tumors, known as rhabdomyosarcomas, are extremely rare.
A sarcoma is a type of tumor that originates in the soft tissues of the body; a rhabdomyosarcoma occurs in the muscle tissue of the heart. Their incidence is estimated at less than 0.1 percent, based on a study of more than 12,000 autopsies, which identified only seven cases of any kind of primary cardiac tumor. (Primary tumors are those that have originated where they are found, and have not spread from some other part of the body.) That said, “most cancers found in the heart have come from elsewhere in the body,” according to Dr. Timothy J. Moynihan of the Mayo Institute, meaning they are secondary tumors.
To understand exactly what he means, it might be necessary to review the fundamentals. Back to (Cancer) Basics Our bodies have an astronomical number of cells — uncountable, really — though one estimate places the number at 37.2 trillion. When we are healthy, our many cells cooperate and share the vast work of our body, all while they go about their separate business of growing, dividing (to provide a replacement for themselves), and then efficiently dying. Cancer, then, is simply an aberration of these cellular processes. Cancer begins when cells start to grow out of control. This is due to damaged DNA, the genetic material carried in the nucleus of each and every cell. Normally, a cell repairs any damaged DNA, or simply dies, but cancer cells do not repair or die. Instead, they divide and make many more abnormal cells with damaged DNA.
Another unusual property possessed by cancer cells is they are able to grow into —invade, really — other tissues. Normal cells cannot do the same. So, when Moynihan says cancers in the heart have come from “elsewhere in the body,” he is talking about just such an invasion — the cancer began somewhere else in the body, but now it has infiltrated the heart. Dr. Mitchell Gaynor, clinical assistant professor at Weill Cornell Medical College, told Medical Daily the most common secondary tumors spreading to the heart “come from the lung, from the esophagus, and you can also see them from the liver, and the stomach. Even nests of leukemia cells form tumors in the heart.” More importantly, all of these different types of tumors “usually go to the right side of the heart,” Gaynor explained. “That’s where the blood enters the heart — on the right side.” But a tumor is a tumor is a tumor, you say. How do doctors know where a tumor originates — especially when a new tumor may appear years later in a part of the body far from the original cancer site? When a new tumor appears, its cells are identical to those of the original tumor. So if a person had pancreatic cancer, say, and it spread to the brain, the tumor appearing in their brain, when viewed through a microscope, would look nothing like the tumor of a person with brain cancer — the cells of this brain tumor would look identical to pancreatic tumor cells. If secondary tumors invade the heart, why is it so rare for primary tumors to develop there?
According to Gaynor, the explanation begins and ends with our genes. The Reason We Don’t Get Heart Cancer As you likely know, we receive half our genes from our mothers, half from our fathers. While it would seem our genetic fate is sealed, “nothing could be further from the truth,” said Gaynor, whose new book on the subject, The Gene Therapy Plan, will be available in 2015. “We understand now how gene expression can be modified throughout your life… and that can create cancer,” he said. In fact, our environment affects which genes become expressed (activated) as well as how frequently they become activated. And carcinogens coming from our food and environment are one of the many factors that influence which genes are activated or not. “A lot of toxins are found in breast tissue, because there are a lot of fat cells there,” Gaynor explained. “And toxins are found wherever there is the most fat.” While our bodies have some defenses against these contaminants, in the form of detoxifying enzymes, and while our bodies are supported by micronutrients which turn on tumor suppressor genes, dangerous toxins found in our fat tissue still modify our genes, which can result in cancers forming in the organs of our bodies, especially those containing fatty tissue. This, then, is why the heart is so exceptional: “There’s not a lot of fatty tissue [in the heart],” Gaynor said. Even more, “the heart’s enclosed in a membrane,” he explained. Known as the pericardium, this fluid-filled sac may itself become engulfed by cancer, with tumors metastasizing to the outside of it, but still it does its job of protecting our precious hearts. So, even though cancer can happen anywhere there are cells, your heart remains virtually immune due to its muscular nature and the assistance of the pericardium.
From the desk of Zedie.
Another study has disputed the relationship between the use of azithromycin, a macrolide antibiotic, and the risk of cardiovascular death.
In a cohort of more than a quarter million young patients with chlamydia, gonorrhea, or both, there were no deaths from cardiovascular causes in the 10 days following treatment with azithromycin, according to Christine Khosropour, MPH, of the University of Washington in Seattle, and colleagues.
Five patients died from other causes in that window, but the risk was not higher with azithromycin compared with other drugs (RR 0.90, 95% CI 0.15-5.40), the researchers reported in a letter to the editor in the New England Journal of Medicine.
“Our findings should be reassuring to healthcare providers who prescribe azithromycin to treat gonorrhea and chlamydia, and they support the conclusion of the CDC that research related to possible cardiac toxicity associated with azithromycin should not lead to a change in current treatment guidelines for STDs,” they wrote.
A study of Medicaid recipients published in May 2012 showed an association between a 5-day course of azithromycin and an elevated risk of cardiovascular death compared with both no antibiotic treatment and treatment with amoxicillin.
Those findings prompted an FDA review that culminated in the agency issuing a warningthat patients with certain risk factors — including existing QT prolongation, bradycardia, and low blood levels of magnesium or potassium — might develop life-threatening cardiac arrhythmias when taking the drug.
In May 2013, another study — this time among Danish individuals ages 18 to 64 — did not show a greater risk of cardiovascular death in patients taking azithromycin compared with those taking penicillin.
In the current study, Khosropour and colleagues further explored the issue in patients with chlamydia, gonorrhea, or both using data from the Oregon Public Health Division for 1996 to 2012 and from Public Health-Seattle and King County for 1993 to 2010.
The study included a total of 260,048 patients who were treated during the study period. The average age of the patients was 24, 65% were female, and 84% had chlamydia.
Overall, 62% of the patients received azithromycin. Of those who did not, 77% were treated with a tetracycline.
The five deaths identified within 10 days of stopping treatment in the study involved two suicides, a homicide, a drug overdose, and rectal cancer. None was related to cardiovascular disease.